Comparisons of anemia, thrombocytopenia, and neutropenia at initiation of HIV antiretroviral therapy in Africa, Asia, and the Americas

International Journal of Infectious Diseases

Volumn 14, Issue 12, 2010, Pages

  Firnhaber, Cynthia ^a   Smeaton, Laura ^b   Saukila, Nasinuku ^c   Flanigan, Timothy ^d   Gangakhedkar, Raman ^e   Kumwenda, Johnstone ^f   La Rosa, Alberto ^g   Kumarasamy, Nagalingeswaran ^h   De Gruttola, Victor ^h   Hakim, James Gita ⁱ   Campbell, Thomas B ^j  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c KAMUZU CENTRAL HOSPITAL   (Malawi)

^d BROWN UNIVERSITY   (United States)

^e NATIONAL AIDS RESEARCH INSTITUTE   (India)

^f UNIVERSITY OF MALAWI   (Malawi)

^g ASOCIACIÓN CIVIL IMPACTA SALUD Y EDUCACIÓN   (Peru)

^h Research Foundation   (India)

ⁱ UNIVERSITY OF ZIMBABWE   (Zimbabwe)

^j UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

more..

Author keywords

Anemia; HIV; Neutropenia; Resource limited countries; Thrombocytopenia

Indexed keywords

ANTIRETROVIRUS AGENT; NEVIRAPINE; ZIDOVUDINE;

ADULT; AFRICA; ANEMIA; ARTICLE; ASIA; CD4+ T LYMPHOCYTE; CENTRAL AMERICA; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GENDER; HEPATITIS B; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; NEUTROPENIA; PREVALENCE; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SOUTH AMERICA; THROMBOCYTE COUNT; THROMBOCYTOPENIA; UNITED STATES;

ADULT; AFRICA; AMERICAS; ANEMIA; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; ASIA; CARIBBEAN REGION; DEVELOPING COUNTRIES; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; NEUTROPENIA; PREVALENCE; SOUTH AMERICA; THROMBOCYTOPENIA; UNITED STATES;

EID: 78649634978     PISSN: 12019712     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijid.2010.08.002     Document Type: Article

References (19)

1. Levine A., Karim R., Mack W., Gravink J., Anastos K., Young M., et al. Neutropenia in human immunodeficiency virus infection: data from the Women's Interagency HIV Study. Arch Intern Med 2006, 166:405-410.
2. Levine A., Berhane K., Karim R., Cohen M., Masri-Lavine L., Young M., et al. Impact of highly active antiretroviral therapy on anemia and relationship between anemia and survival in a large cohort of HIV-infected women: Women's Interagency HIV Study. J Acquir Immune Defic Syndr 2004, 37:1245-1252.
3. Moore R., Keruly J., Chaisson R. Anemia and survival in HIV infection. J Acquir Immune Defic Syndr Hum Retrovirol 1998, 19:29-33.
4. Wikipedia. List of countries by GDP (PPP) per capita. Available at: [accessed November 18, 2009]. http://en.wikipedia.org/wiki/List_of_countries_by_GDP_(PPP)_per_capita.
5. Serjeant G. Mortality from sickle cell anemia disease in Africa. BMJ 2005, 330:432-433.
6. World Health Organization Sickle cell anemia: report by the Secretariat. Secretariat Board Session 117 2005, WHO, Geneva, p. 1-5.
7. Ssali F., Stohr W., Munderi P., Reid A., Walker A.S., Gibb D.M., et al. Prevalence, incidence and predictors of severe anemia with zidovudine-containing regimens in African adults with HIV infections within the DART trial. Antivir Ther 2006, 11:741-749.
8. Semba R.D., Gray G.E. Pathogenesis of anemia during human immunodeficiency virus infection. J Investig Med 2001, 49:225-239.
9. Huffam S., Srasuebkul P., Zhou J., Calmy A., Saphonn V., Kaldor, et al. Prior antiretroviral therapy experience protects against zidovudine-related anemia. HIV Med 2007, 8:465-471.
10. Leiderman I.Z., Greenberg M.L., Adelsberg B.R., Siegal F.P. A glycoprotein inhibitor of in vitro granuloporesis associated with AIDS. Blood 1987, 70:1267-1272.
11. Mauss S., Steinmetz H.T., Willers R., Manegold C., Kochanek M., Haussinger D., et al. Induction of granulocyte colony-stimulating factor by acute febrile infection but not by neutropenia in HIV seropositive individuals. J Acquir Immune Defic Syndr Hum Retrovirol 1997, 14:430-434.
12. Moses A.V., Williams S., Heneveld M.L., Strussenberg J., Rarick M., Loveless M., et al. Human immunodeficiency virus infection of bone marrow endothelium reduces induction of stromal hematopoietic growth factors. Blood 1996, 87:919-925.
13. Murphy M.F., Metcalfe P., Waters H.A., Carnes C.A., Weller I.V., Linch D.C., et al. Incidence and mechanism of neutropenia and thrombocytopenia in patients with human immunodeficiency virus infection. Br J Haematol 1987, 66:337-340.
14. Toure S., Gabillard D., Inwoley A., Seyler C., Gourvellec G., Anglaret X. Incidence of neutropenia in HIV-infected African adults receiving co-trimoxazole prophylaxis: a 6 year cohort study in Abidjan, Côte D'Ivoire. Trans R Soc Trop Med Hyg 2006, 100:785-790.
15. Panasiuk A., Zak J. Autoimmune thrombocytopenia in chronic liver disease. Pol Merkur Lekarsk 2001, 11:487-490.
16. Michalska Z., Stalke P., Witczak-Malinowska K., Lakomy E.A., Sikorska K., Radowska D., et al. Autoimmune reactions in HBV and HCV. Med Sci Monit 2001, 7(Suppl. 1):175-180.
17. Ciernik I.F., Cone R.W., Fehr J., Weber R. Impaired liver function and retroviral activity are risk factors contribution to HIV associated thrombocytopenia. Swiss HIV Cohort Study. AIDS 1999, 13:1913-1920.
18. Fauci A., Lane C. Human immunodeficiency virus disease: AIDS and related disorders. Harrison's principles of internal medicine 2008, McGraw-Hill, New York, Chicago, San Fransisco, Lisbon, London, Madrid, Mexico City, New Dehli, San Jaun Seoul Singapore, Syndey, Toronto, p. 1180. 17th ed. A.S. Fauci, D.C. Kasper, M.D. Branwald, S.L. Hauser, D.L. Longo, J.L. Jameson, J. Loscalzo (Eds.).
19. Division of AIDS (DAIDS) Table for grading the severity of adult and pediatric adverse events December 2004, DAIDS RSC. http://rsc.tech-res.com/safetyandpharmacovigilance/.