Prognostic impact of adenomatous polyposis coli gene expression in osteosarcoma of the extremities

European Journal of Cancer

Volumn 46, Issue 18, 2010, Pages 3307-3315

  Guimarães, Andréa Paiva Gadelha ^a   Rocha, Rafael Malagoli ^a   Da Cunha, Isabela Werneck ^a   Guimarães, Gustavo Cardoso ^a   Carvalho, André Lopes ^a   De Camargo, Beatriz ^a   Lopes, Ademar ^a   Squire, Jeremy Andrew ^c   Soares, Fernando Augusto ^a,b  

^a A C CAMARGO CANCER CENTER   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Catenin; Adenomatous polyposis coli; Cadherin; Osteosarcoma

Indexed keywords

ALKALINE PHOSPHATASE; BETA CATENIN; CADHERIN; WNT PROTEIN;

ADJUVANT CHEMOTHERAPY; ADULT; ARTICLE; CANCER SURVIVAL; COLON POLYPOSIS; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; OSTEOSARCOMA; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION;

ADENOMATOUS POLYPOSIS COLI; ADOLESCENT; ADULT; AGED; BONE NEOPLASMS; CADHERINS; CHILD; EXTREMITIES; FEMALE; GENES, APC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; OSTEOSARCOMA; PROGNOSIS; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 78649634428     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.06.004     Document Type: Article

References (24)

1. J.F. Holland, R.C. Bast Jr., and D.L. Morton Neoplasms of the bone and soft tissue J.F. Holland, R.C. Bast Jr. D.L. Morton, Cancer medicine 1997 Willians and Wilkins Baltimore 2503 2557
2. P.A. Meyers, G. Heller, and J. Healey Chemotherapy for non metastatic osteogenic sarcoma: the Memorial Sloan-Kettering experience J Clin Oncol 10 1992 5 15
3. G. Bacci, S. Ferrari, and F. Bertoni Histologic response of high-grade nonmetastatic osteosarcoma of the extremity to chemotherapy Clin Orthop 386 2001 186 196
4. R.C. Haydon, A. Deyrup, and A. Ishikawa Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma Int J Cancer 102 2002 338 342
5. J. Luo, J. Chen1, and Z. Deng Wnt signaling and human diseases: what are the therapeutic implications? Lab Invest 87 2007 97 103
6. E.M. Rubin, Y. Guo, and K. Tu Wnt inhibitory factor 1 decreases tumorigenesis and metastasis in osteosarcoma Mol Cancer Ther 9 2010 731 741
7. N. Entz-Werle, T. Lavaux, and N. Metzger Involvement of MET/TWIST/APC combination or the potential role of ossification factors in pediatric high-grade osteosarcoma oncogenesis Neoplasia 9 2007 678 688
8. Y. Cai, A.B. Mohseny, and M. Karperien Inactive Wnt/beta-catenin pathway in conventional high-grade osteosarcoma J Pathol 220 2010 24 33
9. B.H. Hoang, T. Kubo, and J.H. Healey Inhibits invasion and motility of saos-2 osteosarcoma cells by modulating the Wnt-catenin pathway Cancer Res 64 2004 2734 2739
10. L.H. Sobin, and Ch. Wittekind TNM classification malignant tumors 2002 John Wiley & Sons New York p. 109-13
11. G. Bacci, S. Ferrari, and A. Longhi High-grade osteosarcoma of the extremity: differences between localized and metastatic tumors at presentation J Pediatr Hematol Oncol 24 2002 27 30
12. A. Rech, C.G. Castro Jr, and J. Mattei Clinical features in osteosarcoma and prognostic implications J Pediatr 80 2004 65 70
13. A.G. Ayala, A.K. Raymond, and N. Jaffe The pathologist's role in the diagnosis and treatment of osteosarcoma in children Hum Pathol 15 1984 258 266
14. B.M. Rossi, A. Lopes, and L.P. Kowalski Prognostic factors in 291 patients with pulmonary metastases submitted to toracotomy Sao Paulo Med J 113 1995 910 916
15. G. Bacci, S. Ferrari, and N. Delepine Predictive factors of histologic response to primary chemotherapy in osteosarcoma of the extremity: study of 272 patients preoperatively treated with high-dose methotrexate, doxorubicin, and cisplatin J Clin Oncol 16 1998 658 663
16. G. Bacci, S. Ferrari, and D. Donati Neoadjuvant chemotherapy for osteosarcoma of the extremity in patients in the fourth and fifth decade of life Oncol Rep 5 1998 1259 1263
17. K. Okada, K.K. Unni, and R.G. Swee High grade surface osteosarcoma: a clinicopathologic study of 46 cases Cancer 85 1999 1044 1054
18. G. Bacci, P. Picci, and S. Ferrari Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities. Results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin Cancer 72 1993 3227 3238
19. M.A. Weiner, M.B. Harris, and M. Lewis Neoadjuvant high-dose methotrexate, cisplatin, and doxorubicin for the management of patients with nonmetastatic osteosarcoma Cancer Treat Rep 70 1986 1431 1432
20. K. Winkler, G. Beron, and R. Kotz Neoadjuvant chemotherapy for osteogenic sarcoma: results of a Cooperative German/Austrian study J Clin Oncol 2 1984 617 624
21. B. Alberts, D. Bray, and J. Lewis Biologia molecular da célula 1997 Artes Médicas Porto Alegre p. 949-1009
22. T. Kashima, J. Kawaguchi, and S. Takeshita Anomalous cadherin expression in osteosarcoma. Possible relationships to metastasis and morphogenesis Am J Pathol 155 1999 1549 1555
23. T. Kashima, K. Nakamura, and J. Kawaguchi Overexpression of cadherins suppresses pulmonary metastasis of osteosarcoma in vivo Int J Cancer 104 2003 147 154
24. H. Monaghan, V.J. Bubb, and R. Sirimujalin Adenomatous polyposis coli (APC), beta-catenin, and cadherin are expressed in human bone and cartilage Histopathology 39 2001 611 619