Sn-protoporphyrin inhibits both heme degradation and hemozoin formation in Rhodnius prolixus midgut

Insect Biochemistry and Molecular Biology

Volumn 40, Issue 12, 2010, Pages 855-860

  Caiaffa, C D ^a   Stiebler, R ^a   Oliveira, M F ^a   Lara, F A ^b   Paiva Silva, G O ^a,c   Oliveira, P L ^a,c  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular INCT EM CNPq   (Brazil)

Author keywords

Hematophagy; Heme; Heme oxygenase; Oxidative stress; Rhodnius prolixus

Indexed keywords

HEME; HEMOPROTEIN; HEMOZOIN; METALLOPORPHYRIN; PROTOPORPHYRIN; PROTOPORPHYRIN TIN;

ANIMAL; ARTICLE; BLOOD; EGG LAYING; FEMALE; GASTROINTESTINAL TRACT; METABOLISM; PHYSIOLOGY; RABBIT; RHODNIUS;

ANIMALS; BLOOD; FEMALE; GASTROINTESTINAL TRACT; HEME; HEMEPROTEINS; METALLOPORPHYRINS; OVIPOSITION; PROTOPORPHYRINS; RABBITS; RHODNIUS;

HEXAPODA; RHODNIUS; RHODNIUS PROLIXUS; VERTEBRATA;

EID: 78649630468     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ibmb.2010.08.005     Document Type: Article

References (30)

1. Dansa-Petretski M., Ribeiro J.M., Atella G.C., Masuda H., Oliveira P.L. Antioxidant role of Rhodnius prolixus heme-binding protein. Protection against heme-induced lipid peroxidation. J. Biol. Chem. 1995, 270:10893-10896.
2. Drummond G.S., Kappas A. Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation. Proc. Natl. Acad. Sci. U S A 1981, 78:6466-6470.
3. Drummond G.S., Kappas A. Chemoprevention of neonatal jaundice: potency of tin-protoporphyrin in an animal model. Science 1982, 217:1250-1252.
4. Garcia E.S., Macarini J.D., Garcia M.L., Ubatuba F.B. Feeding of Rhodnius prolixus in the laboratory. An Acad Bras Cienc 1975, 47:537-545.
5. Graca-Souza A.V., Maya-Monteiro C., Paiva-Silva G.O., Braz G.R., Paes M.C., Sorgine M.H., Oliveira M.F., Oliveira P.L. Adaptations against heme toxicity in blood-feeding arthropods. Insect Biochem. Mol. Biol. 2006, 36:322-335.
6. Jani D., Nagarkatti R., Beatty W., Angel R., Slebodnick C., Andersen J., Kumar S., Rathore D. HDP-a novel heme detoxification protein from the malaria parasite. PLoS Pathog. 2008, 4. e1000053.
7. Kumar S., Bandyopadhyay U. Free heme toxicity and its detoxification systems in human. Toxicol. Lett. 2005, 157:175-188.
8. Lehane M.J. Biology of Blood-sucking Insects 1991, HarperCollins Academic, London.
9. Machado E.A., Oliveira P.L., Moreira M.F., de Souza W., Masuda H. Uptake of Rhodnius heme-binding protein (RHBP) by the ovary of Rhodnius prolixus. Arch. Insect. Biochem. Physiol. 1998, 39:133-143.
10. Mans B.J., Neitz A.W. Adaptation of ticks to a blood-feeding environment: evolution from a functional perspective. Insect Biochem. Mol. Biol. 2004, 34:1-17.
11. Martiney J.A., Cerami A., Slater A.F. Inhibition of hemozoin formation in Plasmodium falciparum trophozoite extracts by heme analogs: possible implication in the resistance to malaria conferred by the beta-thalassemia trait. Mol. Med. 1996, 2:236-246.
12. Montellano P.R. The mechanism of heme oxygenase. Curr. Opin. Chem. Biol. 2000, 4:221-227.
13. Mury F.B., da Silva J.R., Ferreira L.S., dos Santos Ferreira B., de Souza-Filho G.A., de Souza-Neto J.A., Ribolla P.E., Silva C.P., do Nascimento V.V., Machado O.L., Berbert-Molina M.A., Dansa-Petretski M. Alpha-glucosidase promotes hemozoin formation in a blood-sucking bug: an evolutionary history. PLoS One 2009, 4. e6966.
14. Oliveira M.F., d'Avila J.C., Torres C.R., Oliveira P.L., Tempone A.J., Rumjanek F.D., Braga C.M., Silva J.R., Dansa-Petretski M., Oliveira M.A., de Souza W., Ferreira S.T. Haemozoin in Schistosoma mansoni. Mol. Biochem. Parasitol. 2000, 111:217-221.
15. Oliveira M.F., Silva J.R., Dansa-Petretski M., de Souza W., Braga C.M., Masuda H., Oliveira P.L. Haemozoin formation in the midgut of the blood-sucking insect Rhodnius prolixus. FEBS Lett. 2000, 477:95-98.
16. Oliveira M.F., Silva J.R., Dansa-Petretski M., de Souza W., Lins U., Braga C.M., Masuda H., Oliveira P.L. Haem detoxification by an insect. Nature 1999, 400:517-518.
17. Oliveira P.L., Kawooya J.K., Ribeiro J.M., Meyer T., Poorman R., Alves E.W., Walker F.A., Machado E.A., Nussenzveig R.H., Padovan G.J., et al. A heme-binding protein from hemolymph and oocytes of the blood-sucking insect, Rhodnius prolixus. Isolation and characterization. J. Biol. Chem. 1995, 270:10897-10901.
18. Paes M.C., Oliveira M.B., Oliveira P.L. Hydrogen peroxide detoxification in the midgut of the blood-sucking insect, Rhodnius prolixus. Arch. Insect Biochem. Physiol. 2001, 48:63-71.
19. Paiva-Silva G.O., Cruz-Oliveira C., Nakayasu E.S., Maya-Monteiro C.M., Dunkov B.C., Masuda H., Almeida I.C., Oliveira P.L. A heme-degradation pathway in a blood-sucking insect. Proc. Natl. Acad. Sci. U S A 2006, 103:8030-8035.
20. Ryter S.W., Tyrrell R.M. The heme synthesis and degradation pathways: role in oxidant sensitivity. heme oxygenase has both pro- and antioxidant properties. Free. Radic. Biol. Med. 2000, 28:289-309.
21. Schmitt T.H., Frezzatti W.A., Schreier S. Hemin-induced lipid membrane disorder and increased permeability: a molecular model for the mechanism of cell lysis. Arch. Biochem. Biophys. 1993, 307:96-103.
22. Silva J.R., Mury F.B., Oliveira M.F., Oliveira P.L., Silva C.P., Dansa-Petretski M. Perimicrovillar membranes promote hemozoin formation into Rhodnius prolixus midgut. Insect Biochem. Mol. Biol. 2007, 37:523-531.
23. Slater A.F., Swiggard W.J., Orton B.R., Flitter W.D., Goldberg D.E., Cerami A., Henderson G.B. An iron-carboxylate bond links the heme units of malaria pigment. Proc. Natl. Acad. Sci. U S A 1991, 88:325-329.
24. Stiebler R., Timm B.L., Oliveira P.L., Hearne G.R., Egan T.J., Oliveira M.F. On the physico-chemical and physiological requirements of hemozoin formation promoted by perimicrovillar membranes in Rhodnius prolixus midgut. Insect Biochem. Mol. Biol. 2010, 40:284-292.
25. Tappel A.L. Unsaturated lipide oxidation catalyzed by hematin compounds. J. Biol. Chem. 1955, 217:721-733.
26. Teale F.W. Cleavage of the haem-protein link by acid methylethylketone. Biochim. Biophys. Acta 1959, 35:543.
27. Tenhunen R., Marver H.S., Schmid R. Microsomal heme oxygenase. Characterization of the enzyme. J. Biol. Chem. 1969, 244:6388-6394.
28. Wigglesworth V.B. The fate of haemoglobin in Rhodnius prolixus (Hemiptera) and other blood-sucking Arthropods. Proc. R. Soc. Lond. B 1943, 131:313-339.
29. Wijayanti N., Katz N., Immenschuh S. Biology of heme in health and disease. Curr. Med. Chem. 2004, 11:981-986.
30. Wilks A. Heme oxygenase: evolution, structure, and mechanism. Antioxid. Redox Signal. 2002, 4:603-614.