Impaired vascular function in asymptomatic young adult survivors of Hodgkin Lymphoma following mediastinal radiation

Journal of Cancer Survivorship

Volumn 4, Issue 3, 2010, Pages 218-224

  Zelcer, Shayna ^a   Chen, Breanna ^b   Mangel, Joy ^a   Vujovic, Olga ^c   Thiessen Philbrook, Heather R ^d   Reider, Michael ^a   Mahmud, Farid H ^e  

^a LONDON HEALTH SCIENCES CENTRE   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c LONDON REGIONAL CANCER PROGRAM   (Canada)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Cardiotoxicity after cancer therapy; Late effects; Lymphoma

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CASE CONTROL STUDY; CHILD; COMPARATIVE STUDY; CROSS-SECTIONAL STUDY; FEMALE; HODGKIN DISEASE; HUMAN; MALE; MEDIASTINUM TUMOR; PATHOLOGY; PATHOPHYSIOLOGY; PILOT STUDY; RADIATION DOSE; RETROSPECTIVE STUDY; RISK FACTOR; SURVIVOR; VASCULAR DISEASE; VASCULAR ENDOTHELIUM;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CHILD; CROSS-SECTIONAL STUDIES; ENDOTHELIUM, VASCULAR; FEMALE; HODGKIN DISEASE; HUMANS; MALE; MEDIASTINAL NEOPLASMS; PILOT PROJECTS; RADIATION TOLERANCE; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVORS; VASCULAR DISEASES; YOUNG ADULT;

EID: 78649629978     PISSN: 19322259     EISSN: 19322267     Source Type: Journal    
DOI: 10.1007/s11764-010-0138-6     Document Type: Article

References (45)

1. Hudson M, Onciu M, Donaldson S. Hodgkin lymphoma. In: Pizzo P, Poplack D, editors. Principles and practice of pediatric oncology. 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2006. p. 695-721.
2. Adams MJ, Hardenbergh PH, Constine LS, et al. Radiation associated cardiovascular disease. Crit Rev Oncol Hematol. 2003; 45: 55-75.
3. Hull MC, Morris CG, Pepine CJ, et al. Valvular dysfunction and carotid, subclavian, and coronary artery disease in survivors of Hodgkin lymphoma treated with radiation therapy. JAMA. 2003; 290(21): 2831-7.
4. Heidenrich PA, Hancock SL, Lee BK, et al. Asymptomatic cardiac disease following mediastinal radiation. J Am Coll Cardiol. 2003; 42(4): 743-9.
5. Brosius FC, Waller BF, Roberts WC. Radiation heart disease. Analysis of 16 young (aged 15-33 years) necropsy patients who received over 3500 rads to the heart. Am J Med. 1981; 70(3): 519-30.
6. Veinot JP, Edwards WD. Pathology of radiation-induced heart disease: a surgical and autopsy study of 27 cases. Hum Pathol. 1996; 27(8): 766-73.
7. McEniery PT, Dorosti K, Shciavone W, et al. Clinical and angiographic features of coronary artery disease after chest irradiation. Am J Cardiol. 1987; 60: 1020-4.
8. King V, Constine LS, Clark D, et al. Symptomatic coronary artery disease after mantle irradiation for Hodgkin's disease. Int J Radiat Oncol Biol Phys. 1996; 36(4): 881-9.
9. Glanzmann C, Kaufmann P, Jenni R, et al. Cardiac risk after mediastinal irradiaton for Hodgkin's disease. Radiother Oncol. 1998; 46: 51-62.
10. Constine LS, Schwartz RG, Savage DE, et al. Cardiac function, perfusion and morbidity in irradiated long-term survivors of Hodgkin's disease. Int J Radiat Oncol Biol Phys. 1997; 39(4): 897-906.
11. Reinders JG, Heijmen BJM, Olofsen-van Acht MJJ, et al. Ischemic heart disease after mantle field irradiation for Hodgkin's disease in long-term follow-up. Radiother Oncol. 1999; 51: 35-42.
12. Hancock SL, Tucker MA, Hoppe RT. Factors affecting late mortality from heart disease after treatment of Hodgkin's disease. JAMA. 1993; 270(16): 1949-55.
13. Hancock SL, Donaldson SS, Hoppe RT. Cardiac disease following treatment of Hodgkin's disease in children and adolescents. J Clin Oncol. 1993; 11(7): 1208-15.
14. Piovaccari G, Ferretti RM, Prati F, et al. Cardiac disease after chest irradiation for Hodgkin's disease: incidence in 108 patients with long follow-up. Int J Cardiol. 1995; 49: 39-43.
15. Gustavsson A, Eskilsson J, Landberg T. Late cardiac effects after mantle radiotherapy in patients with Hodgkin's disease. Ann Oncol. 1990; 1: 355-63.
16. Silberberg JM, Zarrabi MH. Myocardial infarction in patients treated with mantle radiotherapy. J Clin Oncol. 1989; 7: 541-4.
17. Lipshultz SE, Colan SD, Gleber RD, et al. Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood. N Engl J Med. 1991; 324: 808-15. 1992.
18. Heidenreich PA, Schnittger I, Strauss HW, et al. Screening for coronary artery disease after mediastinal irradiation for Hodgkin's disease. J Clin Oncol. 2007; 25: 43-9.
19. Brunner H, Cockcroft JR, Deanfield J, et al. Endothelial function and dysfunction. Part II: association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension. J Hypertens. 2005; 23: 233-46.
20. Anderson TJ, Uehata A, Gerhard MD, et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol. 1995; 26: 1235-41.
21. Bonetti PO, Pumper GM, Higano ST, et al. Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia. J Am Coll Cardiol. 2004; 44(11): 2137-41.
22. Kuvin JT, Patel AR, Sliney KA, et al. Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitude. Am Heart J. 2003; 146(1): 168-74.
23. Bonetti PO, Barsness GW, Keelan PC, et al. Enhanced external counterpulsation improves endothelial function in patients with symptomatic coronary artery disease. J Am Coll Cardiol. 2003; 41(10): 1761-8.
24. Kuvin JT, Patel AR, Sliney NG, et al. Peripheral vascular endothelial function testing as a non-invasive indicator of coronary artery disease. J Am Coll Cardiol. 2001; 38: 1843-9.
25. Hamburg NH, Keyes MJ, Larson MG. Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study. Circulation. 2008; 117: 2467-74.
26. Mahmud FH, van Uum S, Kanji N, et al. Impaired endothelial function in adolescents with type I diabetes melliutus. J Pediatr. 2008; 152: 557-62.
27. Mahmud FH, Hill DJ, Phil D, et al. Impaired vascular function in obese adolescents with insulin resistance. J Pediatr. 2009; 155(5): 678-82.
28. Tierney ES, Newburger JW, Gauvreau K, et al. Endothelial pulse amplitude testing: feasibility and reproducibility in adolescents. J Pediatr. 2009; 154(6): 901-5.
29. Hay JA, Atkinson S, Halton J. An examination of the reliability of the Habitual Activity Estimation Scale (HAES). In: Proceedings of the Pediatric Work Physiology Symposium, Odense, Denmark, 1995.
30. Kuvin JT, Mammen A, Mooney P, et al. Assessment of peripheral vascular endothelial function in the ambulatory setting. Vasc Med. 2007; 12: 13-6.
31. Children's Oncology Group (COG) Protocol AHODOO31. A phase III study of dose-intensive, response-based chemotherapy and radiation therapy for children and adolescents with newly diagnosed intermediate risk Hodgkin Disease (http://www. childrensoncologygroup. org).
32. Horning SJ, Hoppe RT, Breslin S, Bartlett NL, Brown BW, Rosenberg SA. Stanford V and radiotherapy for locally extensive and advanced Hodgkin's disease: mature results of a prospective clinical trial. J Clin Oncol. 2002; 20(3): 630-7.
33. Children's Cancer Group (CCG) Protocol 5942. Comprehensive study of clinically staged Hodgkin's Disease. Disease (http://www. childrensoncologygroup.org)
34. Connors JM, Klimo P, Adams G, Burns BF, Cooper I, et al. Treatment of advanced Hodgkin's disease with chemotherapy-comparison of MOPP/ABV hybrid regimen with alternating courses of MOPP and ABVD: a report from the National Cancer Institute of Canada clinical trials group. J Clin Oncol. 1997; 15: 1638-45.
35. Stewart JR, Fajardo LF, Gillette SM, et al. Radiation injury to the heart. Int J Radiat Oncol Biol Phys. 1995; 31: 1205-11.
36. Theodoulou M, Seidman AD. Cardiac affects of adjuvant therapy for early breast cancer. Semin Oncol. 2003; 30: 730-9.
37. Beckman JA, Thakore A, Kalinowski BH, et al. Radiation therapy impairs endothelium-dependent vasodilation in humans. J Am Coll Cardiol. 2001; 37: 761-5.
38. Tribble DL, Barcellos-Hoff MH, Chu BM, et al. Ionizing radiation accelerates aortic lesion formation in fat-fed mice via SOD-inhibitable processes. Arterioscler Thromb Vasc Biol. 1999; 19: 1387-92.
39. Carver JR, Shapiro CL, Ng A, et al. American Society of Clinical Oncology clinical evidence review of on the ongoing care of adult cancer survivors: cardiac and pulmonary late effects. J Clin Oncol. 2007; 25(25): 1-18.
40. Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers Version 3. 0. October 2008. http://www. survivorshipguidelines. org.
41. Pihkala J, Happonen JM, Virtanen K, et al. Cardiopulmonary evaluation of exercise tolerance after chest irradiation and anticancer chemotherapy in children and adolescents. Pediatrics. 1995; 95: 722-6.
42. Jurado J, Thompson PD. Prevention of coronary artery disease in cancer patients. Pediatr Blood Cancer. 2005; 44: 620-4.
43. Halcox JPJ, Deanfield JE. Endothelial cell function testing: how does the method help us in evaluating vascular status? Acta Paediatr Suppl. 2004; 446: 48-54.
44. Celermajer DS, Sorenson KE, Bull C, et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet. 1992; 340: 1111-5.
45. Haller MJ, Stein J, Shuster J, et al. Peripheral arterial tonometry demonstrates altered endothelial function in children with type I diabetes. Pediatr Diabetes 2007; 8(4): 193-8.