Immunotoxicity of pyrethroid metabolites in an in vitro model

Environmental Toxicology and Chemistry

Volumn 29, Issue 11, 2010, Pages 2505-2510

  Zhang, Ying ^a   Zhao, Meirong ^b   Jin, Meiqing ^a   Xu, Chao ^b   Wang, Cui ^b   Liu, Weiping ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Cytokine; Cytotoxicity; Metabolites; Monocytes; Pyrethroids

Indexed keywords

ACID DERIVATIVE; APOPTOSIS ASSAYS; CELL APOPTOSIS; CELL VIABILITY; CONTROL GROUPS; CYTOKINES; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOTOXICITY; IN-VITRO; MONOCYTES; MONOCYTIC CELLS; PARENT COMPOUNDS; PYRETHROIDS; SYNTHETIC PYRETHROIDS; TARGET ORGANS; TUMOR NECROSIS FACTORS;

ACIDS; ALDEHYDES; ASSAYS; BIOMOLECULES; BODY FLUIDS; BROMINE COMPOUNDS; CELL DEATH; CYTOTOXICITY; DAMAGE DETECTION; ESTERS; HEALTH RISKS; METABOLITES; RISK ASSESSMENT;

METABOLISM;

3 PHENOXYBENZALDEHYDE; 3 PHENOXYBENZOIC ACID; 3 PHENOXYBENZOIC ALCOHOL; ALCOHOL DERIVATIVE; ALDEHYDE DERIVATIVE; CIPERMETHRIN; CYHALOTHRIN; CYPHENOTHRIN; INTERLEUKIN 12P70; NITROBLUE TETRAZOLIUM; PHENOTHRIN; PYRETHROID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALDEHYDE; APOPTOSIS; HEALTH RISK; IMMUNOASSAY; INHIBITION; METABOLITE; NUMERICAL MODEL; POLLUTION EXPOSURE; PYRETHROID; RISK ASSESSMENT; SECRETION; TUMOR; VIABILITY;

APOPTOSIS; ARTICLE; CELL VIABILITY; CHEMICAL STRUCTURE; CYTOKINE RELEASE; CYTOTOXICITY; CYTOTOXICITY TEST; ENZYME LINKED IMMUNOSORBENT ASSAY; HEALTH HAZARD; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOTOXICITY; IN VITRO STUDY; METABOLITE; MONOCYTE; PRIORITY JOURNAL; RISK ASSESSMENT; UPREGULATION;

APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOTOXINS; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; PYRETHRINS; STEREOISOMERISM;

EID: 78649587013     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.298     Document Type: Article

References (37)

1. Kelce WR, Stone CR, Laws SC, Gray LE, Kemppainen JA, Wilson EM. 1995. Persistent DDT metabolite p, p'-DDE is a potent androgen receptor antagonist. Nature 375: 581-585.
2. Osanoa O, Admiraala W, Klamerc HJC, Pastorc D, Bleekera EAJ. 2002. Comparative toxic and genotoxic effects of chloroacetanilides, formamidines and their degradation products on Vibrio fischeri and Chironomus riparius. Environ Pollut 119: 195-202.
3. Sinclair CJ, Boxall ABA. 2003. Assessing the ecotoxicity of pesticide transformation products. Environ Sci Technol 37: 4617-4625.
4. Thomas PT. 1995. Pesticide-induced immunotoxicity: Are Great Lakes residents at risk? Environ Health Perspect 103: 55-61.
5. Banerjee BD, Koner BC, Ray A. 1996. Immunotoxicity of pesticides: Perspectives and trends. Indian J Exp Biol 34: 723-733.
6. Lee SJ, Gan JY, Kabashima J. 2002. Recovery of synthetic pyrethroids in water samples during storage and extraction. J Agric Food Chem 50: 7194-7198.
7. Spurlock F, Lee M. 2008. Synthetic pyrethroid use patterns, properties, and environmental effects. In Gan JY, Superlock F, Hendley P, Weston D, eds, Synthetic Pyrethroids Occurrence and Behavior in Aquatic Environments, Section One: Overview and Occurrence. American Chemical Society, Washington, DC, pp 6-9.
8. Go V, Garey J, Wolff MS, Pogo BGT. 1999. Estrogenic potential of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line. Environ Health Perspect 107: 173-177.
9. Kale M, Rathore N, John S, Bhatnagar D. 1999. Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: A possible involvement of reactive oxygen species. Toxicol Lett 105: 197-205.
10. Blaylock BL, Abdel-Nasser M, McCarty SM, Knesel JA, Tolson KM, Ferguson PW, Mehendale HM. 1995. Suppression of cellular immune responses in BALB/c mice following oral exposure to permethrin. Bull Environ Contam Toxicol 54: 768-774.
11. Diel F, Horrl B, Borck H, Irman-Florjanc T. 2003. Pyrethroid insecticides influence the signal transduction in T helper lymphocytes from atopic and nonatopic subjects. Inflamm Res 52: 154-163.
12. Miyamoto J. 1976. Degradation, metabolism and toxicity of synthetic pyrethroids. Environ Health Perspect 14: 15-28.
13. Leng G, Kühn KH, Idel H. 1997. Biological monitoring of pyrethroids in blood and pyrethroid metabolites in urine: Applications and limitations. Sci Total Environ 199: 173-181.
14. Tomigahara Y, Onogi M, Saito K, Kaneko H, Nakatsuka I, Yamane S. 1997. Metabolism of tetramethrin isomers in rat: IV. Tissues responsible for formation of reduced and hydrated metabolites. Xenobiotica 27: 961-971.
15. Maloney Se, Maule A, Smith ARW. 1992. Transformation of synthetic pyrethroid insecticides by a thermophilic Bacillus sp. Arch Microbiol 158: 282-286.
16. Lu C, Barr D, Pearson M, Bartell S, Bravo R. 2006. A longitudinal approach to assessing urban and suburban children's exposure to pyrethroid pesticides. Environ Health Perspect 114: 1419-1423.
17. Madsen C, Claesson MH, Röpke C. 1996. Immunotoxicity of the pyrethroid insecticides deltamethrin and α-cypermethrin. Toxicology 107: 219-227.
18. Sun H, Xu XL, Xu LC, Song L, Hong X, Chen JF, Cui LB, Wang XR. 2007. Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay. Chemosphere 66: 474-479.
19. Tyler CR, Beresford N, van der Woning M, Sumpter JP, Thorpe K. 2000. Metabolism and environmental degradation of pyrethroid insecticides produce compounds with endocrine activities. Environ Toxicol Chem 19: 801-809.
20. Sundstrom C, Nilsson K. 1976. Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int J Cancer 17: 565-577.
21. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. 1995. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression. J Immunol Methods 184: 39-51.
22. House RV. 1998. Theory and practice of cytokine assessment in immunotoxicology. Methods 19: 17-27.
23. Agency for Toxic Substances and Disease Registry. 2008. Toxicological Profile for Pyrethrins and Pyrethroids. Department of Health and Human Services, Atlanta, GA, USA.
24. Anand SS, Bruckner JV, Haines WT, Muralidhara S, Fisher JW, Padilla S. 2006. Characterization of deltamethrin metabolism by rat plasma and liver microsomes. Toxicol Appl Pharmacol 212: 156-166.
25. Godin SJ, Crow JA, Scollon EJ, Hughes MF, DeVito MJ, Ross MK. 2007. Identification of rat and human cytochrome P450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerate. Drug Metab Dispos 35: 1664-1671.
26. Shono T, Ohsawa K, Casida JE. 1979. Metabolism of trans and cis-permethrin, trans- and cis-cypermethrin and decamethrin by microsomal enzymes. J Agric Food Chem 27: 316-325.
27. EXTOXNET. 1994. Pyrethrins and pyrethroids. Pesticide information profiles. Extension Toxicology Network. Oregon State University, Corvallis, OR, USA.
28. Diel F, Detscher M, Schock B, Ennis M. 1998. In vitro effects of the pyrethroid S-bioallethrin on lymphocytes and basophils from atopic and nonatopic subjects. Allergy 53: 1052-1059.
29. Prater MR, Gogal RM Jr, Blaylock BL, Longstreth J, Holladay SD. 2002. Single-dose topical exposure to the pyrethroid insecticide, permethrin in C57BL/6N mice: Effects on thymus and spleen. Food Chem Toxicol 40: 1863-1873.
30. Enan E, Pinkerton KE, Peake J, Matsumura F. 1996. Deltamethrin-induced thymus atrophy in male BALB/c mice. Biochem Pharmacol 51: 447-454.
31. Baud V, Karin M. 2001. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol 11: 372-377.
32. Chang HY, Yang X. 2000. Proteases for cell suicide: Functions and regulation of caspases. Microbiol Mol Biol Rev 64: 821-846.
33. Idriss HT, Naismith JH. 2000. TNF α and the TNF receptor superfamily: Structure-function relationship(s). Microsc Res Tech 50: 184-195.
34. Wajant H, Grell M, Scheurich P. 1999. TNF receptor associated factors in cytokine signaling. Cytokine Growth Factor Rev 10: 15-26.
35. Arch RH, Gedrich RW, Thompson CB. 1998. Tumor necrosis factor receptor-associated factors (TRAFs)-α family of adapter proteins that regulates life and death. Genes Dev 12: 2821-2830.
36. Michelangeli F, Robson MJ, East JM, Lee AG. 1990. The conformation of pyrethroids bound to lipid bilayers. Biochim Biophys Acta 1028: 49-57.
37. Moya-Quiles MR, Munoz-Delgado E, Vidal CJ. 1996. Effects of the pyrethroid insecticide permethrin on membrane fluidity. Chem Phys Lipids 79: 21-28.