-
1
-
-
33644752296
-
Intake of aspartame vs the acceptable daily intake
-
Butchko HH, Stargel WW, Comer CP, Mayhew DA, Benninger C, Blackburn GL, de Sonneville LMJ, Geha RF, Hertelendy Z, Kostner A, Leon AS, Liepa GU, McMartin KE, Mendnhall CL, Munro IC, Novotny EJ, Renwick AG, Schiffman SS, Schomer DL, Shaywitz BA, Spiers PA, Tephly TR, Thomas JA, Trefz FK. 2002. Intake of aspartame vs the acceptable daily intake. Regul Toxicol Pharmacol 35: S13-S16.
-
(2002)
Regul Toxicol Pharmacol
, vol.35
-
-
Butchko, H.H.1
Stargel, W.W.2
Comer, C.P.3
Mayhew, D.A.4
Benninger, C.5
Blackburn, G.L.6
de Sonneville, L.M.J.7
Geha, R.F.8
Hertelendy, Z.9
Kostner, A.10
Leon, A.S.11
Liepa, G.U.12
McMartin, K.E.13
Mendnhall, C.L.14
Munro, I.C.15
Novotny, E.J.16
Renwick, A.G.17
Schiffman, S.S.18
Schomer, D.L.19
Shaywitz, B.A.20
Spiers, P.A.21
Tephly, T.R.22
Thomas, J.A.23
Trefz, F.K.24
more..
-
2
-
-
0011212735
-
Attuazione della direttiva n. 86/609/CEE in materia di protezione degli animali utilizzati a fini sperimentali o ad altri fini scientifici [in Italian]
-
Decreto Legislativo 116.
-
Decreto Legislativo 116. 1992. Attuazione della direttiva n. 86/609/CEE in materia di protezione degli animali utilizzati a fini sperimentali o ad altri fini scientifici [in Italian]. Suppl Ordinario Gazz Ufficiale 40: 5-25.
-
(1992)
Suppl Ordinario Gazz Ufficiale
, vol.40
, pp. 5-25
-
-
-
3
-
-
48549094492
-
Summary of chemically induced pulmonary lesions in the National Toxicology Program (NTP) toxicology and carcinogenesis studies
-
Dixon D, Herbert RA, Kissling GE, Brix AE, Miller RA, Maronpot RR. 2008. Summary of chemically induced pulmonary lesions in the National Toxicology Program (NTP) toxicology and carcinogenesis studies. Toxicol Pathol 36: 428-439.
-
(2008)
Toxicol Pathol
, vol.36
, pp. 428-439
-
-
Dixon, D.1
Herbert, R.A.2
Kissling, G.E.3
Brix, A.E.4
Miller, R.A.5
Maronpot, R.R.6
-
4
-
-
46649108278
-
Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to a new long-term carcinogenicity study on aspartame. Question number EFSA-Q-2005-122. Adopted on 3 May 2006
-
European Food Safety Authority (EFSA).
-
European Food Safety Authority (EFSA). 2006. Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to a new long-term carcinogenicity study on aspartame. Question number EFSA-Q-2005-122. Adopted on 3 May 2006. EFSA J 356: 1-44.
-
(2006)
EFSA J
, vol.356
, pp. 1-44
-
-
-
5
-
-
0344988510
-
Aspartame: Commissioner's final decision
-
Food and Drug Administration (FDA).
-
Food and Drug Administration (FDA). 1981. Aspartame: Commissioner's final decision. Fed Reg 46: 38285-38308.
-
(1981)
Fed Reg
, vol.46
, pp. 38285-38308
-
-
-
6
-
-
0842263443
-
Food additives permitted for direct addition to food for human consumption: Aspartame
-
Food and Drug Administration (FDA).
-
Food and Drug Administration (FDA). 1983. Food additives permitted for direct addition to food for human consumption: Aspartame. Fed Reg 48: 31376-31382.
-
(1983)
Fed Reg
, vol.48
, pp. 31376-31382
-
-
-
7
-
-
0842328274
-
Food additives permitted for direct addition to food for human consumption: Aspartame
-
Food and Drug Administration (FDA).
-
Food and Drug Administration (FDA). 1996. Food additives permitted for direct addition to food for human consumption: Aspartame. Fed Reg 61: 33654-33656.
-
(1996)
Fed Reg
, vol.61
, pp. 33654-33656
-
-
-
8
-
-
0018881961
-
01 study)
-
In, Staffa JA, Mehlman MA, editors., Park Forest South, IL, Pathotox Publishers, Inc., p
-
01 study). Park Forest South, IL: Pathotox Publishers, Inc., p 121-138.
-
(1979)
Biologic and morphologic characteristics of hepatocellular lesions in BALB/c female mice fed 2-acetylaminofluorene
, pp. 121-138
-
-
Frith, C.H.1
Kodell, R.L.2
Littlefield, N.A.3
-
10
-
-
0004017862
-
Proteins
-
New York, John Wiley & Sons, p
-
Haschemeyer RH, Haschemeyer AEV. 1973. Proteins. New York: John Wiley & Sons, p 11-30.
-
(1973)
, pp. 11-30
-
-
Haschemeyer, R.H.1
Haschemeyer, A.E.V.2
-
11
-
-
0026556048
-
Value of historical controls in the interpretation of rodent neoplasm data
-
Haseman J. 1992. Value of historical controls in the interpretation of rodent neoplasm data. Drug Inf J 26: 191-200.
-
(1992)
Drug Inf J
, vol.26
, pp. 191-200
-
-
Haseman, J.1
-
12
-
-
0028901961
-
Data analysis: Statistical analysis and use of historical control data
-
Haseman J. 1995. Data analysis: Statistical analysis and use of historical control data. Regul Toxicol Pharmacol 21: 52-59.
-
(1995)
Regul Toxicol Pharmacol
, vol.21
, pp. 52-59
-
-
Haseman, J.1
-
13
-
-
0021148721
-
Use of historical control data in carcinogenicity studies in rodents
-
Haseman J, Huff JE, Boorman GA. 1984. Use of historical control data in carcinogenicity studies in rodents. Toxicol Pathol 12: 126-135.
-
(1984)
Toxicol Pathol
, vol.12
, pp. 126-135
-
-
Haseman, J.1
Huff, J.E.2
Boorman, G.A.3
-
14
-
-
0034970078
-
Carcinogenesis bioassays: Study duration and biological relevance
-
Haseman J, Melnick R, Tomatis L, Huff J. 2001. Carcinogenesis bioassays: Study duration and biological relevance. Food Chem Toxicol 39(7): 739-744.
-
(2001)
Food Chem Toxicol
, vol.39
, Issue.7
, pp. 739-744
-
-
Haseman, J.1
Melnick, R.2
Tomatis, L.3
Huff, J.4
-
15
-
-
78649628337
-
-
Hazardous Substances Data Bank., TOXNET: Toxicological Data Network. Available: [accessed August 3, 2005].
-
Hazardous Substances Data Bank. 2005. TOXNET: Toxicological Data Network. Available: [accessed August 3, 2005].
-
(2005)
-
-
-
16
-
-
0036962522
-
Chemicals studied and evaluated in long-term carcinogenesis bioassays by both the Ramazzini Foundation and the National Toxicology Program. In tribute to Cesare Maltoni and David Rall
-
Huff J. 2002. Chemicals studied and evaluated in long-term carcinogenesis bioassays by both the Ramazzini Foundation and the National Toxicology Program. In tribute to Cesare Maltoni and David Rall. Ann N Y Acad Sci 982: 208-230.
-
(2002)
Ann N Y Acad Sci
, vol.982
, pp. 208-230
-
-
Huff, J.1
-
17
-
-
0043287924
-
Absence of carcinogenic activity in Fischer rats and B6C3F1 mice following 103-week inhalation exposures to toluene
-
Huff J. 2003. Absence of carcinogenic activity in Fischer rats and B6C3F1 mice following 103-week inhalation exposures to toluene. Int J Occup Environ Health 9(2): 138-146.
-
(2003)
Int J Occup Environ Health
, vol.9
, Issue.2
, pp. 138-146
-
-
Huff, J.1
-
18
-
-
58849098055
-
The limits of two-year bioassay exposure regimens for identifying chemical carcinogens
-
Huff J, Jacobson MF, Davis DL. 2008. The limits of two-year bioassay exposure regimens for identifying chemical carcinogens. Environ Health Perspect 116(11): 1439-1442.
-
(2008)
Environ Health Perspect
, vol.116
, Issue.11
, pp. 1439-1442
-
-
Huff, J.1
Jacobson, M.F.2
Davis, D.L.3
-
20
-
-
0015787035
-
Transplacental induction of tumors and malformations in rats treated with some chemical carcinogens
-
International Agency for Research on Cancer (IARC).
-
International Agency for Research on Cancer (IARC). 1973. Transplacental induction of tumors and malformations in rats treated with some chemical carcinogens. IARC Sci Publ 4: 100-111.
-
(1973)
IARC Sci Publ
, vol.4
, pp. 100-111
-
-
-
21
-
-
0031587502
-
Results of long-term experimental carcinogenicity studies of the effects of gasoline, correlated fuels and major gasoline aromatics on rats
-
Maltoni C, Ciliberti A, Pinto C, Soffritti M, Belpoggi F, Menarini L. 1997. Results of long-term experimental carcinogenicity studies of the effects of gasoline, correlated fuels and major gasoline aromatics on rats. Ann N Y Acad Sci 837: 15-52.
-
(1997)
Ann N Y Acad Sci
, vol.837
, pp. 15-52
-
-
Maltoni, C.1
Ciliberti, A.2
Pinto, C.3
Soffritti, M.4
Belpoggi, F.5
Menarini, L.6
-
22
-
-
70349680623
-
Biological basis of differential susceptibility to hepatocarcinogenesis among mouse strains
-
Maronpot RR. 2009. Biological basis of differential susceptibility to hepatocarcinogenesis among mouse strains. J Toxicol Pathol 22: 11-33.
-
(2009)
J Toxicol Pathol
, vol.22
, pp. 11-33
-
-
Maronpot, R.R.1
-
23
-
-
0003532399
-
Aspartame physiology and biochemistry
-
In, Stegink LD, Filer LJ, Jr., editors., New York, Dekker, p
-
Mattews DM. 1984. Absorption of peptides, amino acids, and their methylated derivatives. In: Stegink LD, Filer LJ, Jr., editors. Aspartame physiology and biochemistry. New York: Dekker, p 29-46.
-
(1984)
Absorption of peptides, amino acids, and their methylated derivatives
, pp. 29-46
-
-
Mattews, D.M.1
-
24
-
-
0003532399
-
Aspartame physiology and biochemistry
-
In, Stegink LD, Filer LJ, Jr., editors., New York, Dekker, p
-
Mazur RH. 1984. Discovery of aspartame. In: Stegink LD, Filer LJ, Jr., editors. Aspartame physiology and biochemistry. New York: Dekker, p 3-9.
-
(1984)
Discovery of aspartame
, pp. 3-9
-
-
Mazur, R.H.1
-
25
-
-
0003627588
-
Biochemistry
-
New York, Academic Press, p
-
Metzler DE. 1977. Biochemistry. New York: Academic Press, p 90-107.
-
(1977)
, pp. 90-107
-
-
Metzler, D.E.1
-
26
-
-
78649579762
-
Aspartame physiology and biochemistry
-
In, Stegink LD, Filer LJ, Jr., editors., New York, Dekker, p
-
Molinary SV. 1984. Preclinical studies of aspartame in nonprimate animals. In: Stegink LD, Filer LJ, Jr., editors. Aspartame physiology and biochemistry. New York: Dekker, p 289-306.
-
(1984)
Preclinical studies of aspartame in nonprimate animals
, pp. 289-306
-
-
Molinary, S.V.1
-
27
-
-
78649591105
-
-
National Toxicology Program (NTP)., Genetically Modified Model Report. Toxicology Studies of Aspartame (CAS NO. 22839-47-0) in Genetically Modified (FVB Tg.AC Hemizygous) and B6.129-Cdkn2atm1Rdp (N2) Deficient Mice and Carcinogenicity Studies of Aspartame in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Feed Studies). NTP GMM1. National Toxicology Program, Research Triangle Park. Available at: .
-
National Toxicology Program (NTP). 2005. Genetically Modified Model Report. Toxicology Studies of Aspartame (CAS NO. 22839-47-0) in Genetically Modified (FVB Tg.AC Hemizygous) and B6.129-Cdkn2atm1Rdp (N2) Deficient Mice and Carcinogenicity Studies of Aspartame in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Feed Studies). NTP GMM1. National Toxicology Program, Research Triangle Park. Available at.
-
(2005)
-
-
-
31
-
-
0033403085
-
Mega-experiments to identify and assess diffuse carcinogenic risks
-
Soffritti M, Belpoggi F, Minardi F, Bua L, Maltoni C. 1999. Mega-experiments to identify and assess diffuse carcinogenic risks. Ann N Y Acad Sci 895: 34-55.
-
(1999)
Ann N Y Acad Sci
, vol.895
, pp. 34-55
-
-
Soffritti, M.1
Belpoggi, F.2
Minardi, F.3
Bua, L.4
Maltoni, C.5
-
32
-
-
0036960610
-
Ramazzini Foundation cancer program: History and major projects, life-span carcinogenicity bioassay design, chemicals studied, and results
-
Soffritti M, Belpoggi F, Minardi F, Maltoni C. 2002. Ramazzini Foundation cancer program: History and major projects, life-span carcinogenicity bioassay design, chemicals studied, and results. Ann N Y Acad Sci 982: 26-45.
-
(2002)
Ann N Y Acad Sci
, vol.982
, pp. 26-45
-
-
Soffritti, M.1
Belpoggi, F.2
Minardi, F.3
Maltoni, C.4
-
33
-
-
9344237107
-
Life-time carcinogenicity bioassays of toluene given bay stomach tube to Sprague-Dawley rats
-
Soffritti M, Belpoggi F, Padovani M, Lauriola M, Degli Esposti D, Minardi F. 2004. Life-time carcinogenicity bioassays of toluene given bay stomach tube to Sprague-Dawley rats. Eur J Oncol 9: 91-102.
-
(2004)
Eur J Oncol
, vol.9
, pp. 91-102
-
-
Soffritti, M.1
Belpoggi, F.2
Padovani, M.3
Lauriola, M.4
Degli Esposti, D.5
Minardi, F.6
-
35
-
-
33644771206
-
First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats
-
Soffritti M, Belpoggi F, Degli Esposti D, Lambertini L, Tibaldi E, Rigano A. 2006. First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats. Environ Health Perspect 114: 379-385.
-
(2006)
Environ Health Perspect
, vol.114
, pp. 379-385
-
-
Soffritti, M.1
Belpoggi, F.2
Degli Esposti, D.3
Lambertini, L.4
Tibaldi, E.5
Rigano, A.6
-
36
-
-
34748884376
-
Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats
-
Soffritti M, Belpoggi F, Tibaldi E, Esposti DD, Lauriola M. 2007. Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats. Environ Health Perspect 115: 1293-1297.
-
(2007)
Environ Health Perspect
, vol.115
, pp. 1293-1297
-
-
Soffritti, M.1
Belpoggi, F.2
Tibaldi, E.3
Esposti, D.D.4
Lauriola, M.5
-
37
-
-
38449110761
-
Consequences of exposure to carcinogens beginning during developmental life
-
Soffritti M, Belpoggi F, Esposti DD, Falcioni L, Bua L. 2008. Consequences of exposure to carcinogens beginning during developmental life. Basic Clin Pharmacol Toxicol 102(2): 118-124.
-
(2008)
Basic Clin Pharmacol Toxicol
, vol.102
, Issue.2
, pp. 118-124
-
-
Soffritti, M.1
Belpoggi, F.2
Esposti, D.D.3
Falcioni, L.4
Bua, L.5
-
38
-
-
0032103434
-
Formaldehyde derived from dietary aspartame binds to tissue components in vivo
-
Trocho C, Pardo R, Rafecas I, Virgili J, Remesar X, Fernandez-Lopez JA, Alemany M. 1998. Formaldehyde derived from dietary aspartame binds to tissue components in vivo. Life Sci 63: 337-349.
-
(1998)
Life Sci
, vol.63
, pp. 337-349
-
-
Trocho, C.1
Pardo, R.2
Rafecas, I.3
Virgili, J.4
Remesar, X.5
Fernandez-Lopez, J.A.6
Alemany, M.7
|