Serum choline levels in patients with stable angina and acute coronary syndromes: Relation to the severity of coronary artery disease

Coronary Artery Disease

Volumn 21, Issue 8, 2010, Pages 466-471

  Şentürk, Tunay ^a   Tütüncü, Ahmet ^a   Özdemir, Bülent ^a   Özdabakoǧlu, Osman ^a   Aydin, Sami ^a   Baran, Ibrahim ^a   Güllülü, Sümeyye ^a   Savci, Vahide ^a   Aydinlar, Ali ^a  

^a ULUDAG UNIVERSITY   (Turkey)

Author keywords

acute coronary syndrome; choline; coronary artery disease; stable angina pectoris

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CHOLESTEROL; CHOLINE; CREATINE KINASE MB; CREATININE; GLUCOSE; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITRATE; TRIACYLGLYCEROL; TROPONIN I;

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY ARTERY OBSTRUCTION; CREATINE KINASE BLOOD LEVEL; CREATININE BLOOD LEVEL; DISEASE SEVERITY; FEMALE; GLUCOSE BLOOD LEVEL; HEART MUSCLE INJURY; HEMOGLOBIN BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOSPITAL ADMISSION; HUMAN; MALE; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCORING SYSTEM; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; STABLE ANGINA PECTORIS; TRIACYLGLYCEROL BLOOD LEVEL;

ACUTE CORONARY SYNDROME; ADULT; AGED; ANGINA PECTORIS; BIOLOGICAL MARKERS; CHI-SQUARE DISTRIBUTION; CHOLINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CORONARY ANGIOGRAPHY; CORONARY STENOSIS; FEMALE; HUMANS; MALE; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TROPONIN I; TURKEY; UP-REGULATION;

EID: 78649528602     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/MCA.0b013e32833bdf39     Document Type: Article

References (19)

1. Apple FS, Wu AH, Mair J, Ravkilde J, Panteghini M, Tate J, et al. Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome. Clin Chem 2005; 51:810-824. (Pubitemid 40577917)
2. Haslam RJ, Coorssen JR. Evidence that activation of phospholipase D can mediate secretion from permeabilized platelets. Adv Exp Med Biol 1993; 344:149-164.
3. Gomez-Munoz A, Martens JS, Steinbrecher UP. Stimulation of phospholipase D activity by oxidized LDL in mouse peritoneal macrophages. Arterioscler Thromb Vasc Biol 2000; 20:135-143.
4. Cox DA, Cohen ML. Relationship between phospholipase D activation and endothelial vasomotor dysfunction in rabbit aorta. J Pharmacol Exp Ther 1997; 283:305-311.
5. Möckel M, Danne O, Muller R, Vollert JO, Muller C, Lueders C, et al. Development of an optimized multimarker strategy for early risk assessment of patients with acute coronary syndromes. Clin Chim Acta 2008; 393:103-109.
6. Danne O, Mockel M, Lueders C, Mugge C, Zschunke GA, Lufft H, et al. Prognostic implications of elevated whole blood choline levels in acute coronary syndromes. Am J Cardiol 2003; 91:1060-1067.
7. Danne O, Lueders C, Storm C, Frei U, Mockel M. Whole blood choline and plasma choline in acute coronary syndromes: Prognostic and pathophysiological implications. Clin Chim Acta 2007; 383:103-109.
8. Body R, Griffith CA, Keevil B, McDowell G, Carley S, Ferguson J, et al. Choline for diagnosis and prognostication of acute coronary syndromes in the Emergency Department. Clin Chim Acta 2009; 404:89-94.
9. LeLeiko RM, Vaccari CS, Sola S, Merchant N, Nagamia SH, Thoenes M, Khan BV. Usefulness of elevations in serum choline and free F2-isoprostane to predict 30-day cardiovascular outcomes in patients with acute coronary syndrome. Am J Cardiol 2009; 104:638-643.
10. Thygesen K, Alpert JS,White HD, Jaffe AS, Apple FS, Galvani M, et al. ESC/ ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction: universal definition of myocardial infarction. Circulation 2007; 116:2634-2653.
11. Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol 1983; 51:606.
12. Davies MJ. Stability and instability: Two faces of coronary atherosclerosis - The Paul Dudley White Lecture 1995. Circulation 1996; 94:2013-2020.
13. O'Brien KD, Pineda C, Chiu WS, Bowen R, Deeg MA. Glycosylphosphatidylinositol-specific phospholipase D is expressed by macrophages in human atherosclerosis and colocalizes with oxidation epitopes. Circulation 1999; 99:2876-2882.
14. Houle MG, Bourgoin S. Regulation of phospholipase D by phosphorylation dependent mechanisms. Biochim Biophys Acta 1999; 1439:135-149.
15. Shaikh NA, Downar E. Time course of changes in porcine myocardial phospholipid levels during ischemia: A reassessment of the lysolipid hypothesis. Circ Res 1981; 49:316-325.
16. Deves R, Reyes G, Krupka RM. The carrier reorientation step in erythrocyte choline transport: PH effects and the involvement of a carrier ionizing group. J Membr Biol 1986; 93:165-175.
17. Collinson PO, Gaze DC. Biomarkers of cardiovascular damage. Med Princ Pract 2007; 16:247-261.
18. Danne O, Möckel M. Choline in acute coronary syndrome: An emerging biomarker with implications for the integrated assessment of plaque vulnerability. Expert Rev Mol Diagn 2010; 10:159-171.
19. Shah PK. Mechanisms of plaque vulnerability and rupture. J Am Coll Cardiol 2003; 41:15S-22S.