Inorganic phosphate (Pi) modulates the expression of key regulatory proteins of the inorganic pyrophosphate (PPi) metabolism in TGF-β1- stimulated chondrocytes

Bio-Medical Materials and Engineering

Volumn 20, Issue 3-4, 2010, Pages 209-215

  Hamade, Tala ^a   Bianchi, Arnaud ^a   Sebillaud, Sylvie ^a   Netter, Patrick ^a   Jouzeau, Jean Yves ^a   Cailotto, Frédéric ^a  

^a Biopôle de l Université de Lorraine   (France)

Author keywords

ANK; chondrocyte; Inorganic phosphate pyrophosphate; PC 1; TGF 1

Indexed keywords

ALKALINE PHOSPHATASE; ANK; ARTICULAR CHONDROCYTES; CALCIUM PHOSPHATE DEPOSITION; CHONDROCYTES; CHONDROGENIC CELLS; EXTRACELLULAR; INORGANIC PHOSPHATE/PYROPHOSPHATE; INORGANIC PHOSPHATES; INORGANIC PYROPHOSPHATE; MEMBRANE PROTEINS; PATHOPHYSIOLOGICAL; PC-1; REGULATORY PROTEIN; STIMULATORY EFFECTS; WESTERN BLOTS;

BIOLOGICAL MEMBRANES; BODY FLUIDS; CALCIUM PHOSPHATE; CELL CULTURE; LAWS AND LEGISLATION; PHOSPHATASES; POLYMERASE CHAIN REACTION;

PROTEINS;

PHOSPHATE; PYROPHOSPHATE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL; ARTICLE; CARTILAGE CELL; CELL CULTURE; DRUG EFFECT; GENE EXPRESSION REGULATION; MALE; METABOLISM; PHYSIOLOGY; RAT; WISTAR RAT;

ANIMALS; CELLS, CULTURED; CHONDROCYTES; DIPHOSPHATES; GENE EXPRESSION REGULATION; MALE; PHOSPHATES; RATS; RATS, WISTAR; TRANSFORMING GROWTH FACTOR BETA1;

EID: 78649514672     PISSN: 09592989     EISSN: None     Source Type: Journal    
DOI: 10.3233/BME-2010-0634     Document Type: Conference Paper

References (17)

1. H.K. Ea and F. Liote, Advances in understanding calcium-containing crystal disease, Curr. Opin. Rheumatol. 21 (2009), 150-157.
2. P.T. Cheng and K.P. Pritzker, Pyrophosphate, phosphate ion interaction: effects on calcium pyrophosphate and calcium hydroxyapatite crystal formation in aqueous solutions, J. Rheumatol. 10 (1983), 769-777.
3. A.M. Ho, M.D. Johnson and D.M. Kingsley, Role of the mouse ank gene in control of tissue calcification and arthritis, Science 289 (2000), 265-270.
4. J. Caverzasio and J.P. Bonjour, Characteristics and regulation of Pi transport in osteogenic cells for bone metabolism, Kidney Int. 49 (1996), 975-980.
5. L.M. Ryan, R.L. Wortmann, B. Karas, M.P. Lynch and D.J. McCarty, Pyrophosphohydrolase activity and inorganic py-rophosphate content of cultured human skin fibroblasts. Elevated levels in some patients with calcium pyrophosphate dihydrate deposition disease, J. Clin. Invest. 77 (1986), 1689-1693.
6. Y. Xu, K.P. Pritzker and T.F. Cruz, Characterization of chondrocyte alkaline phosphatase as a potential mediator in the dissolution of calcium pyrophosphate dihydrate crystals, J. Rheumatol. 21 (1994), 912-919.
7. A.K. Rosenthal, B.A. McCarty, H.S. Cheung and L.M. Ryan, A comparison of the effect of transforming growth factor beta 1 on pyrophosphate elaboration from various articular tissues, Arthritis Rheum. 36 (1993), 539-542.
8. J. Hirose, L.M. Ryan and I. Masuda, Up-regulated expression of cartilage intermediate-layer protein and ANK in articular hyaline cartilage from patients with calcium pyrophosphate dihydrate crystal deposition disease, Arthritis Rheum. 46 (2002), 3218-3229.
9. P. Sohn, M. Crowley, E. Slattery and R. Serra, Developmental and TGF-beta-mediated regulation of Ank mRNA expression in cartilage and bone, Osteoarthr. Cartil. 10 (2002), 482-490.
10. M. Lotz, F. Rosen, G. McCabe, J. Quach, F. Blanco, J. Dudler, J. Solan, J. Goding, J.E. Seegmiller and R. Terkeltaub, In-terleukin 1 beta suppresses transforming growth factor-induced inorganic pyrophosphate (PPi) production and expression of the PPi-generating enzyme PC-1 in human chondrocytes, Proc. Natl. Acad. Sci. USA 92 (1995), 10364-10368.
11. G. Palmer, J. Guicheux, J.P. Bonjour and J. Caverzasio, Transforming growth factor-beta stimulates inorganic phosphate transport and expression of the type III phosphate transporter Glvr-1 in chondrogenic ATDC5 cells, Endocrinology 141 (2000), 2236-2243.
12. F. Cailotto, A. Bianchi, S. Sebillaud, N. Venkatesan, D. Moulin, J.Y. Jouzeau and P. Netter, Inorganic pyrophosphate generation by transforming growth factor-beta-1 is mainly dependent on ANK induction by Ras/Raf-1/extracellular signal-regulated kinase pathways in chondrocytes, Arthritis Res. Ther. 9 (2007), R122.
13. R. Garimella, X. Bi, H.C. Anderson and N.P. Camacho, Nature of phosphate substrate as a major determinant of mineral type formed in matrix vesicle-mediated in vitro mineralization: An FTIR imaging study, Bone 38 (2006), 811-817.
14. A.K. Rosenthal and L.M. Ryan, Probenecid inhibits transforming growth factor-beta 1 induced pyrophosphate elaboration by chondrocytes, J. Rheumatol. 21 (1994), 896-900.
15. T.A. Denison, C.F. Koch, I.M. Shapiro, Z. Schwartz and B.D. Boyan, Inorganic phosphate modulates responsiveness to 24,25(OH)2D3 in chondrogenic ATDC5 cells, J. Cell Biochem. 107 (2009), 155-162.
16. M. Ito, Y. Sakai, M. Furumoto, H. Segawa, S. Haito, S. Yamanaka, R. Nakamura, M. Kuwahata and K. Miyamoto, Vitamin D and phosphate regulate fibroblast growth factor-23 in K-562 cells, Am. J. Physiol. Endocrinol. Metab. 288 (2005), E1101-E1109.
17. K. Miyamoto, M. Ito, H. Segawa and M. Kuwahata, Secondary hyperparathyroidism and phosphate sensing in parathyroid glands, J. Med. Invest. 47 (2000), 118-122.