Multi-locus test conditional on confirmed effects leads to increased power in genome-wide association studies

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Ma, Li ^a,b   Han, Shizhong ^c   Yang, Jing ^a   Da, Yang ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b Program on Infrastructure Policy   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL;

ANALYTIC METHOD; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC SCREENING; GENOME ANALYSIS; METABOLITE; MULTILOCUS ASSOCIATION TEST; PHENOTYPE; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; ALGORITHM; BIOLOGY; CARDIOVASCULAR DISEASE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; HUMAN GENOME; METHODOLOGY; QUANTITATIVE TRAIT LOCUS; REPRODUCIBILITY;

ALGORITHMS; CARDIOVASCULAR DISEASES; COMPUTATIONAL BIOLOGY; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; REPRODUCIBILITY OF RESULTS;

EID: 78649512175     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015006     Document Type: Article

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