TROPICS 1: A phase III, randomized, double-blind, placebo-controlled study of tenecteplase for restoration of function in dysfunctional central venous catheters

Journal of Vascular and Interventional Radiology

Volumn 21, Issue 12, 2010, Pages 1852-1858

  Gabrail, Nashat ^a   Sandler, Eric ^b   Charu, Veena ^c   Anas, Nick ^d   Lim, Eduardo ^e   Blaney, Martha ^f   Ashby, Mark ^f   Gillespie, Barbara S ^g   Begelman, Susan M ^f  

^a Gabrail Cancer Center   (United States)

^b NEMOURS CHILDREN S CLINIC   (United States)

^c Pacific Cancer Medical Center   (United States)

^d CHILDREN S HOSPITAL OF ORANGE COUNTY   (United States)

^e Private Practice   (United States)

^f GENENTECH INC   (United States)

^g IQVIA   (United States)

Author keywords

Abbreviations; Adverse event; AE; Catheter related bloodstream infection; Central venous catheter; CI; Confidence interval; CRBSI; CVC; Deep vein thrombosis; DVT; ICH; Intracranial hemorrhage; MITT; Modified intent to treat; PBO TNK TNK

Indexed keywords

TENECTEPLASE;

ADULT; AGED; ARTICLE; CENTRAL VENOUS CATHETER; CENTRAL VENOUS CATHETERIZATION; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG EXPOSURE; DRUG INSTILLATION; HUMAN; MAJOR CLINICAL STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD;

ADOLESCENT; ADULT; AGED; CATHETERIZATION, CENTRAL VENOUS; CATHETERS, INDWELLING; CHI-SQUARE DISTRIBUTION; DOUBLE-BLIND METHOD; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; MALE; MIDDLE AGED; PLACEBO EFFECT; REGIONAL BLOOD FLOW; THROMBOLYTIC THERAPY; THROMBOSIS; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME; UNITED STATES; YOUNG ADULT;

EID: 78649511988     PISSN: 10510443     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvir.2010.09.002     Document Type: Article

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