Design of three-component vaccines against group A streptococcal infections: Importance of spatial arrangement of vaccine components

Journal of Medicinal Chemistry

Volumn 53, Issue 22, 2010, Pages 8041-8046

  Abdel Aal, Abu Baker M ^a   Zaman, Mehfuz ^a   Fujita, Yoshio ^a   Batzloff, Michael R ^b   Good, Michael F ^b   Toth, Istvan ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; IMMUNOGLOBULIN G; LIPID; LIPOPEPTIDE; LYSINE; PEPTIDE VACCINE; STREPTOCOCCUS VACCINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFECT; DRUG STRUCTURE; FEMALE; GROUP A STREPTOCOCCAL INFECTION; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; MOUSE; NONHUMAN; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, INTRANASAL; ANIMALS; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; FEMALE; LIPOPEPTIDES; MICE; PROTEIN STRUCTURE, SECONDARY; STREPTOCOCCAL INFECTIONS; STREPTOCOCCAL VACCINES; STREPTOCOCCUS PYOGENES; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 78649503620     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm1007787     Document Type: Article

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