The protective role of brain size in Alzheimer's disease

Expert Review of Neurotherapeutics

Volumn 10, Issue 12, 2010, Pages 1799-1801

  Whitwell, Jennifer L ^a  

^a MAYO CLINIC   (United States)

Author keywords

Alzheimer's disease; atrophy; brain reserve; cognition; head circumference

Indexed keywords

AMYLOID; FLUORODEOXYGLUCOSE F 18;

ALZHEIMER DISEASE; BRAIN ATROPHY; BRAIN GROWTH; BRAIN RESERVE; BRAIN SIZE; COGNITION; COGNITIVE DEFECT; DEMENTIA; DISEASE ASSOCIATION; HEAD CIRCUMFERENCE; HUMAN; MENTAL PERFORMANCE; MINI MENTAL STATE EXAMINATION; NERVE CELL PLASTICITY; NEUROPATHOLOGY; NEUROPROTECTION; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY;

EID: 78649502300     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/ern.10.168     Document Type: Note

References (13)

1. Brookmeyer R, Johnson E, Ziegler-Graham K, Arrighi HM. Forecasting the global burden of Alzheimer's disease. Alzheimer's Dement. 3, 186-191 (2007).
2. Katzman R, Terry R, DeTeresa R et al. Clinical, pathological, and neurochemical changes in dementia: a subgroup with preserved mental status and numerous neocortical plaques. Ann. Neurol. 23, 138-144 (1998).
3. Wolf H, Julin P, Gertz HJ, Winblad B, Wahlund LO. Intracranial volume in mild cognitive impairment, Alzheimer's disease and vascular dementia: evidence for brain reserve? Int. J. Geriatr. Psychiatry 19, 995-1007 (2004).
4. Espinosa PS, Kryscio RJ, Mendiondo MS et al. Alzheimer's disease and head circumference. J. Alzheimers Dis. 9, 77-80 (2006).
5. Christensen H, Batterham PJ, Mackinnon AJ, Anstey KJ, Wen W, Sachdev PS. Education, atrophy, and cognitive change in an epidemiological sample in early old age. Am. J. Geriatr. Psychiatry 17, 218-226 (2009).
6. Perneczky R, Wagenpfeil S, Lunetta KL et al. Head circumference, atrophy, and cognition: implications for brain reserve in Alzheimer disease. Neurology 75, 137-142 (2010).
7. Barnes LL, Wilson RS, Bienias JL, Schneider JA, Evans DA, Bennett DA. Sex differences in the clinical manifestations of Alzheimer disease pathology. Arch. Gen. Psychiatry 62, 685-691 (2005).
8. Whitwell JL, Josephs KA, Murray ME et al. MRI correlates of neurofbrillary tangle pathology at autopsy: a voxel-based morphometry study. Neurology 71, 743-749 (2008).
9. Stern Y. Cognitive reserve. Neuropsychologia 47, 2015-2028 (2009).
10. Roe CM, Xiong C, Miller JP, Cairns NJ, Morris JC. Interaction of neuritic plaques and education predicts dementia. Alzheimer Dis. Assoc. Disord. 22, 188-193 (2008).
11. Brickman AM, Siedlecki KL, Muraskin J et al. White matter hyperintensities and cognition: testing the reserve hypothesis. Neurobiol. Aging DOI: 10.1016/j. neurobiolaging.2009.10.013 (2009) (Epub ahead of print).
12. Rentz DM, Locascio JJ, Becker JA et al. Cognition, reserve, and amyloid deposition in normal aging. Ann. Neurol. 67, 353-364 (2010).
13. Sachdev PS, Valenzuela M. Brain and cognitive reserve. Am. J. Geriatr. Psychiatry 17, 175-178 (2009).