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Volumn 20, Issue 3-4, 2010, Pages 145-158

Chondrogenic potential of bone marrow- and adipose tissue-derived adult human mesenchymal stem cells

Author keywords

adipose tissue derived stem cell; BMP 2; Bone marrow derived stem cell; chondrogenesis; FGF 2; hypoxia; TGF 3

Indexed keywords

BMP-2; BONE MARROW-DERIVED STEM CELL; CHONDROGENESIS; FGF-2; HYPOXIA; STEM CELL;

EID: 78649496561     PISSN: 09592989     EISSN: None     Source Type: Journal    
DOI: 10.3233/BME-2010-0626     Document Type: Conference Paper
Times cited : (108)

References (49)
  • 1
    • 47049122353 scopus 로고    scopus 로고
    • Differentiation of adult human mesenchymal stem cells: Chondrogenic effect of BMP-2
    • Paris French
    • A.M. Freyria, S. Courtes and F. Mallein-Gerin, Differentiation of adult human mesenchymal stem cells: chondrogenic effect of BMP-2, Pathol. Biol. (Paris) 56 (2008), 326-333 (in French).
    • (2008) Pathol. Biol. , vol.56 , pp. 326-333
    • Freyria, A.M.1    Courtes, S.2    Mallein-Gerin, F.3
  • 2
    • 33947169304 scopus 로고    scopus 로고
    • Lessons from musculoskeletal stem cell research: The key to successful regenerative medicine development
    • D. McGonagle, C. De Bari, P. Arnold and E. Jones, Lessons from musculoskeletal stem cell research: the key to successful regenerative medicine development, Arthritis Rheum. 56 (2007), 714-721.
    • (2007) Arthritis Rheum. , vol.56 , pp. 714-721
    • McGonagle, D.1    De Bari, C.2    Arnold, P.3    Jones, E.4
  • 3
    • 57349172324 scopus 로고    scopus 로고
    • Isolation of human bone marrow mesenchymal stem cells using different membrane markers: Comparison of colony/cloning efficiency, differentiation potential, and molecular profile, Tissue Eng
    • M.C. Kastrinaki, I. Andreakou, P. Charbord and H.A. Papadaki, Isolation of human bone marrow mesenchymal stem cells using different membrane markers: comparison of colony/cloning efficiency, differentiation potential, and molecular profile, Tissue Eng. Part C Methods 14 (2008), 333-339.
    • (2008) Part C Methods , vol.14 , pp. 333-339
    • Kastrinaki, M.C.1    Andreakou, I.2    Charbord, P.3    Papadaki, H.A.4
  • 5
    • 66249121386 scopus 로고    scopus 로고
    • BMP-2 Enhances TGF-beta3-mediated chondrogenic differentiation of human bone marrow multipotent mesenchymal stromal cells in alginate bead culture
    • B. Shen, A. Wei, H. Tao, A.D. Diwan and D.D. Ma, BMP-2 Enhances TGF-beta3-mediated chondrogenic differentiation of human bone marrow multipotent mesenchymal stromal cells in alginate bead culture, Tissue Eng. Part A 15 (2009), 1311-1320.
    • (2009) Tissue Eng. Part A , vol.15 , pp. 1311-1320
    • Shen, B.1    Wei, A.2    Tao, H.3    Diwan, A.D.4    Ma, D.D.5
  • 7
    • 43549099478 scopus 로고    scopus 로고
    • In vitro chondrogenic differentiation of human mesenchy-mal stem cells in collagen microspheres: Influence of cell seeding density and collagen concentration
    • T.Y. Hui, K.M. Cheung, W.L. Cheung, D. Chan and B.P. Chan, In vitro chondrogenic differentiation of human mesenchy-mal stem cells in collagen microspheres: influence of cell seeding density and collagen concentration, Biomaterials 29 (2008), 3201-3212.
    • (2008) Biomaterials , vol.29 , pp. 3201-3212
    • Hui, T.Y.1    Cheung, K.M.2    Cheung, W.L.3    Chan, D.4    Chan, B.P.5
  • 9
    • 0032168880 scopus 로고    scopus 로고
    • Differential effects of local application of BMP-2 or TGF-beta1 on both articular cartilage composition and osteophyte formation
    • H.M. van Beuningen, H.L. Glansbeek, P.M. van der Kraan and W.B. van den Berg, Differential effects of local application of BMP-2 or TGF-beta1 on both articular cartilage composition and osteophyte formation, Osteoarthr. Cartil. 6 (1998), 306-317.
    • (1998) Osteoarthr. Cartil. , vol.6 , pp. 306-317
    • Van Beuningen, H.M.1    Glansbeek, H.L.2    Kraan Der Van, P.M.3    Berg Den Van, W.B.4
  • 10
    • 33846490361 scopus 로고    scopus 로고
    • Differential expression pattern of extracellular matrix molecules during chondrogenesis of mesenchymal stem cells from bone marrow and adipose tissue
    • A.T. Mehlhorn, P. Niemeyer, S. Kaiser, G. Finkenzeller, G.B. Stark, N.P. Sudkamp and H. Schmal, Differential expression pattern of extracellular matrix molecules during chondrogenesis of mesenchymal stem cells from bone marrow and adipose tissue, Tissue Eng. 12 (2006), 2853-2862.
    • (2006) Tissue Eng. , vol.12 , pp. 2853-2862
    • Mehlhorn, A.T.1    Niemeyer, P.2    Kaiser, S.3    Finkenzeller, G.4    Stark, G.B.5    Sudkamp, N.P.6    Schmal, H.7
  • 12
    • 23244455905 scopus 로고    scopus 로고
    • In vitro cartilage tissue engineering with 3D porous aqueous-derived silk scaffolds and mesenchymal stem cells
    • Y. Wang, U.J. Kim, D.J. Blasioli, H.J. Kim and D.L. Kaplan, In vitro cartilage tissue engineering with 3D porous aqueous-derived silk scaffolds and mesenchymal stem cells, Biomaterials 26 (2005), 7082-7094.
    • (2005) Biomaterials , vol.26 , pp. 7082-7094
    • Wang, Y.1    Kim, U.J.2    Blasioli, D.J.3    Kim, H.J.4    Kaplan, D.L.5
  • 13
    • 77951458865 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditions
    • W.S. Khan, A.B. Adesida, S.R. Tew, E.T. Lowe and T.E. Hardingham, Bone marrow-derived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditions, J. Orthop. Res. 28 (2010), 834-840.
    • (2010) J. Orthop. Res. , vol.28 , pp. 834-840
    • Khan, W.S.1    Adesida, A.B.2    Tew, S.R.3    Lowe, E.T.4    Hardingham, T.E.5
  • 15
    • 23644456193 scopus 로고    scopus 로고
    • Comparison of human stem cells derived from various mesenchymal tissues: Superiority of synovium as a cell source
    • Y. Sakaguchi, I. Sekiya, K. Yagishita and T. Muneta, Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source, Arthritis Rheum. 52 (2005), 2521-2529.
    • (2005) Arthritis Rheum. , vol.52 , pp. 2521-2529
    • Sakaguchi, Y.1    Sekiya, I.2    Yagishita, K.3    Muneta, T.4
  • 16
    • 67650682082 scopus 로고    scopus 로고
    • Combination of transforming growth factor-beta2 and bone morphogenetic protein 7 enhances chondrogenesis from adipose tissue-derived mesenchymal stem cells
    • H.J. Kim and G.I. Im, Combination of transforming growth factor-beta2 and bone morphogenetic protein 7 enhances chondrogenesis from adipose tissue-derived mesenchymal stem cells, Tissue Eng. Part A 15 (2009), 1543-1551.
    • (2009) Tissue Eng. Part A , vol.15 , pp. 1543-1551
    • Kim, H.J.1    Im, G.I.2
  • 17
    • 0035674325 scopus 로고    scopus 로고
    • Effect of oxygen tension and alginate encapsulation on restoration of the differentiated phenotype of passaged chondrocytes
    • C.L. Murphy and A. Sambanis, Effect of oxygen tension and alginate encapsulation on restoration of the differentiated phenotype of passaged chondrocytes, Tissue Eng. 7 (2001), 791-803.
    • (2001) Tissue Eng. , vol.7 , pp. 791-803
    • Murphy, C.L.1    Sambanis, A.2
  • 18
    • 36549065233 scopus 로고    scopus 로고
    • Fetal growth plate: A developmental model of cellular adaptation to hypoxia
    • S. Provot and E. Schipani, Fetal growth plate: a developmental model of cellular adaptation to hypoxia, Ann. N. Y. Acad. Sci. 1117 (2007), 26-39.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1117 , pp. 26-39
    • Provot, S.1    Schipani, E.2
  • 19
    • 0025948422 scopus 로고
    • Alternatively spliced type II procollagen mRNAs define distinct populations of cells during vertebral development: Differential expression of the amino-propeptide
    • L.J. Sandell, N. Morris, J.R. Robbins and M.B. Goldring, Alternatively spliced type II procollagen mRNAs define distinct populations of cells during vertebral development: differential expression of the amino-propeptide, J. Cell Biol. 114 (1991), 1307-1319.
    • (1991) J. Cell Biol. , vol.114 , pp. 1307-1319
    • Sandell, L.J.1    Morris, N.2    Robbins, J.R.3    Goldring, M.B.4
  • 20
    • 0033503715 scopus 로고    scopus 로고
    • Reexpression of type IIA procollagen by adult articular chondrocytes in osteoarthritic cartilage
    • T. Aigner, Y. Zhu, H.H. Chansky, F.A. Matsen 3rd, W.J. Maloney and L.J. Sandell, Reexpression of type IIA procollagen by adult articular chondrocytes in osteoarthritic cartilage, Arthritis Rheum. 42 (1999), 1443-1450.
    • (1999) Arthritis Rheum. , vol.42 , pp. 1443-1450
    • Aigner, T.1    Zhu, Y.2    Chansky, H.H.3    Matsen III, F.A.4    Maloney, W.J.5    Sandell, L.J.6
  • 21
    • 0025346774 scopus 로고
    • Differential expression of a cysteine-rich domain in the amino-terminal propeptide of type II (cartilage) procollagen by alternative splicing of mRNA
    • M.C. Ryan and L.J. Sandell, Differential expression of a cysteine-rich domain in the amino-terminal propeptide of type II (cartilage) procollagen by alternative splicing of mRNA, J. Biol. Chem. 265 (1990), 10334-10339.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10334-10339
    • Ryan, M.C.1    Sandell, L.J.2
  • 22
    • 0033535331 scopus 로고    scopus 로고
    • Type IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-beta1 and BMP-2
    • Y. Zhu, A. Oganesian, D.R. Keene and L.J. Sandell, Type IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-beta1 and BMP-2, J. Cell Biol. 144 (1999), 1069-1080.
    • (1999) J. Cell Biol. , vol.144 , pp. 1069-1080
    • Zhu, Y.1    Oganesian, A.2    Keene, D.R.3    Sandell, L.J.4
  • 23
    • 33750955152 scopus 로고    scopus 로고
    • Dose-and time-dependent effects of cyclic hydrostatic pressure on transforming growth factor-beta3-induced chondroge-nesis by adult human mesenchymal stem cells in vitro
    • K. Miyanishi, M.C. Trindade, D.P. Lindsey, G.S. Beaupre, D.R. Carter, S.B. Goodman, D.J. Schurman and R.L. Smith, Dose-and time-dependent effects of cyclic hydrostatic pressure on transforming growth factor-beta3-induced chondroge-nesis by adult human mesenchymal stem cells in vitro, Tissue Eng. 12 (2006), 2253-2262.
    • (2006) Tissue Eng. , vol.12 , pp. 2253-2262
    • Miyanishi, K.1    Trindade, M.C.2    Lindsey, D.P.3    Beaupre, G.S.4    Carter, D.R.5    Goodman, S.B.6    Schurman, D.J.7    Smith, R.L.8
  • 24
    • 33750321974 scopus 로고    scopus 로고
    • Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice
    • K. Pelttari, A. Winter, E. Steck, K. Goetzke, T. Hennig, B.G. Ochs, T. Aigner and W. Richter, Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice, Arthritis Rheum. 54 (2006), 3254-3266.
    • (2006) Arthritis Rheum. , vol.54 , pp. 3254-3266
    • Pelttari, K.1    Winter, A.2    Steck, E.3    Goetzke, K.4    Hennig, T.5    Ochs, B.G.6    Aigner, T.7    Richter, W.8
  • 25
    • 36249000024 scopus 로고    scopus 로고
    • Chondrogenic differentiation of human bone marrow stem cells in transwell cultures: Generation of scaffold-free cartilage
    • A.D. Murdoch, L.M. Grady, M.P. Ablett, T. Katopodi, R.S. Meadows and T.E. Hardingham, Chondrogenic differentiation of human bone marrow stem cells in transwell cultures: generation of scaffold-free cartilage, Stem Cells 25 (2007), 2786-2796.
    • (2007) Stem Cells , vol.25 , pp. 2786-2796
    • Murdoch, A.D.1    Grady, L.M.2    Ablett, M.P.3    Katopodi, T.4    Meadows, R.S.5    Hardingham, T.E.6
  • 26
    • 0035882056 scopus 로고    scopus 로고
    • Chondrogenic differentiation of mesenchymal stem cells from bone marrow: Differentiation-dependent gene expression of matrix components
    • F. Barry, R.E. Boynton, B. Liu and J.M. Murphy, Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation- dependent gene expression of matrix components, Exp. Cell Res. 268 (2001), 189-200.
    • (2001) Exp. Cell Res. , vol.268 , pp. 189-200
    • Barry, F.1    Boynton, R.E.2    Liu, B.3    Murphy, J.M.4
  • 27
    • 16344377055 scopus 로고    scopus 로고
    • FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells
    • L.A. Solchaga, K. Penick, J.D. Porter, V.M. Goldberg, A.I. Caplan and J.F. Welter, FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells, J. Cell. Physiol. 203 (2005), 398-409.
    • (2005) J. Cell. Physiol. , vol.203 , pp. 398-409
    • Solchaga, L.A.1    Penick, K.2    Porter, J.D.3    Goldberg, V.M.4    Caplan, A.I.5    Welter, J.F.6
  • 28
    • 33847260281 scopus 로고    scopus 로고
    • Differentiation of human mesenchymal stem cells and articular chondrocytes: Analysis of chondrogenic potential and expression pattern of differentiation-related transcription factors
    • C. Karlsson, C. Brantsing, T. Svensson, H. Brisby, J. Asp, T. Tallheden and A. Lindahl, Differentiation of human mesenchymal stem cells and articular chondrocytes: analysis of chondrogenic potential and expression pattern of differentiation-related transcription factors, J. Orthop. Res. 25 (2007), 152-163.
    • (2007) J. Orthop. Res. , vol.25 , pp. 152-163
    • Karlsson, C.1    Brantsing, C.2    Svensson, T.3    Brisby, H.4    Asp, J.5    Tallheden, T.6    Lindahl, A.7
  • 32
    • 33746958820 scopus 로고    scopus 로고
    • Limitations of using aggrecan and type X collagen as markers of chondrogenesis in mesenchymal stem cell differentiation
    • F. Mwale, D. Stachura, P. Roughley and J. Antoniou, Limitations of using aggrecan and type X collagen as markers of chondrogenesis in mesenchymal stem cell differentiation, J. Orthop. Res. 24 (2006), 1791-1798.
    • (2006) J. Orthop. Res. , vol.24 , pp. 1791-1798
    • Mwale, F.1    Stachura, D.2    Roughley, P.3    Antoniou, J.4
  • 33
    • 45849105176 scopus 로고    scopus 로고
    • PTHrP promotes chondrogenesis and suppresses hypertrophy from both bone marrow-derived and adipose tissue-derived MSCs
    • Y.J. Kim, H.J. Kim and G.I. Im, PTHrP promotes chondrogenesis and suppresses hypertrophy from both bone marrow-derived and adipose tissue-derived MSCs, Biochem. Biophys. Res. Commun. 373 (2008), 104-108.
    • (2008) Biochem. Biophys. Res. Commun. , vol.373 , pp. 104-108
    • Kim, Y.J.1    Kim, H.J.2    Im, G.I.3
  • 34
    • 51849083414 scopus 로고    scopus 로고
    • Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter
    • P. Zimmermann, S. Boeuf, A. Dickhut, S. Boehmer, S. Olek and W. Richter, Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter, Arthritis Rheum. 58 (2008), 2743-2753.
    • (2008) Arthritis Rheum. , vol.58 , pp. 2743-2753
    • Zimmermann, P.1    Boeuf, S.2    Dickhut, A.3    Boehmer, S.4    Olek, S.5    Richter, W.6
  • 35
    • 0037007146 scopus 로고    scopus 로고
    • In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis
    • I. Sekiya, J.T. Vuoristo, B.L. Larson and D.J. Prockop, In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis, Proc. Natl. Acad. Sci. USA 99 (2002), 4397-4402.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 4397-4402
    • Sekiya, I.1    Vuoristo, J.T.2    Larson, B.L.3    Prockop, D.J.4
  • 36
    • 18844447203 scopus 로고    scopus 로고
    • Comparison of effect of BMP-2,-4, and-6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma
    • I. Sekiya, B.L. Larson, J.T. Vuoristo, R.L. Reger and D.J. Prockop, Comparison of effect of BMP-2,-4, and-6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma, Cell Tissue Res. 320 (2005), 269-276.
    • (2005) Cell Tissue Res. , vol.320 , pp. 269-276
    • Sekiya, I.1    Larson, B.L.2    Vuoristo, J.T.3    Reger, R.L.4    Prockop, D.J.5
  • 37
    • 75749116750 scopus 로고    scopus 로고
    • Impact of growth factors and PTHrP on early and late chondrogenic differentiation of human mesenchymal stem cells
    • S. Weiss, T. Hennig, R. Bock, E. Steck and W. Richter, Impact of growth factors and PTHrP on early and late chondrogenic differentiation of human mesenchymal stem cells, J. Cell. Physiol. 223 (2010), 84-93.
    • (2010) J. Cell. Physiol. , vol.223 , pp. 84-93
    • Weiss, S.1    Hennig, T.2    Bock, R.3    Steck, E.4    Richter, W.5
  • 38
    • 0346496061 scopus 로고    scopus 로고
    • BMP2 initiates chon-drogenic lineage development of adult human mesenchymal stem cells in high-density culture
    • B. Schmitt, J. Ringe, T. Haupl, M. Notter, R. Manz, G.R. Burmester, M. Sittinger and C. Kaps, BMP2 initiates chon-drogenic lineage development of adult human mesenchymal stem cells in high-density culture, Differentiation 71 (2003), 567-577.
    • (2003) Differentiation , vol.71 , pp. 567-577
    • Schmitt, B.1    Ringe, J.2    Haupl, T.3    Notter, M.4    Manz, R.5    Burmester, G.R.6    Sittinger, M.7    Kaps, C.8
  • 39
    • 40949099450 scopus 로고    scopus 로고
    • Cell specific differences between human adipose-derived and mesenchymal-stromal cells despite similar differentiation potentials
    • D. Noel, D. Caton, S. Roche, C. Bony, S. Lehmann, L. Casteilla, C. Jorgensen and B. Cousin, Cell specific differences between human adipose-derived and mesenchymal-stromal cells despite similar differentiation potentials, Exp. Cell Res. 314 (2008), 1575-1584.
    • (2008) Exp. Cell Res. , vol.314 , pp. 1575-1584
    • Noel, D.1    Caton, D.2    Roche, S.3    Bony, C.4    Lehmann, S.5    Casteilla, L.6    Jorgensen, C.7    Cousin, B.8
  • 41
    • 77049091365 scopus 로고    scopus 로고
    • Optimization of a culture medium for the differentiation of preadipocytes into adipocytes in a monolayer
    • C. Lequeux, C. Auxenfans, A. Mojallal, M. Sergent and O. Damour, Optimization of a culture medium for the differentiation of preadipocytes into adipocytes in a monolayer, Biomed. Mater. Eng. 19 (2009), 283-291.
    • (2009) Biomed. Mater. Eng. , vol.19 , pp. 283-291
    • Lequeux, C.1    Auxenfans, C.2    Mojallal, A.3    Sergent, M.4    Damour, O.5
  • 42
    • 33644874153 scopus 로고    scopus 로고
    • High-throughput aggregate culture system to assess the chondrogenic potential of mesenchymal stem cells
    • K.J. Penick, L.A. Solchaga and J.F. Welter, High-throughput aggregate culture system to assess the chondrogenic potential of mesenchymal stem cells, Biotechniques 39 (2005), 687-691.
    • (2005) Biotechniques , vol.39 , pp. 687-691
    • Penick, K.J.1    Solchaga, L.A.2    Welter, J.F.3
  • 43
    • 21844451610 scopus 로고    scopus 로고
    • Optimization of dynamic culture conditions: Effects on biosynthetic activities of chondrocytes grown in collagen sponges
    • A.M. Freyria, Y. Yang, H. Chajra, C.F. Rousseau, M.C. Ronziere, D. Herbage and A.J. El Haj, Optimization of dynamic culture conditions: effects on biosynthetic activities of chondrocytes grown in collagen sponges, Tissue Eng. 11 (2005), 674-684.
    • (2005) Tissue Eng. , vol.11 , pp. 674-684
    • Freyria, A.M.1    Yang, Y.2    Chajra, H.3    Rousseau, C.F.4    Ronziere, M.C.5    Herbage, D.6    El Haj, A.J.7
  • 44
    • 33744905343 scopus 로고    scopus 로고
    • Activation by IL-1 of bovine articular chondrocytes in culture within a 3D collagen-based scaffold. An in vitro model to address the effect of compounds with therapeutic potential in osteoarthritis
    • D. Cortial, J. Gouttenoire, C.F. Rousseau, M.C. Ronziere, N. Piccardi, P. Msika, D. Herbage, F. Mallein-Gerin and A.M. Freyria, Activation by IL-1 of bovine articular chondrocytes in culture within a 3D collagen-based scaffold. An in vitro model to address the effect of compounds with therapeutic potential in osteoarthritis, Osteoarthr. Cartil. 14 (2006), 631-640.
    • (2006) Osteoarthr. Cartil. , vol.14 , pp. 631-640
    • Cortial, D.1    Gouttenoire, J.2    Rousseau, C.F.3    Ronziere, M.C.4    Piccardi, N.5    Msika, P.6    Herbage, D.7    Mallein-Gerin, F.8    Freyria, A.M.9
  • 48
    • 43949115205 scopus 로고    scopus 로고
    • Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells
    • M.B. Mueller and R.S. Tuan, Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells, Arthritis Rheum. 58 (2008), 1377-1388.
    • (2008) Arthritis Rheum. , vol.58 , pp. 1377-1388
    • Mueller, M.B.1    Tuan, R.S.2
  • 49
    • 77953835241 scopus 로고    scopus 로고
    • Low oxygen tension during incubation periods of chondrocyte expansion is sufficient to enhance postexpansion chondrogenesis
    • J.H. Henderson, N.M. Ginley, A.I. Caplan, C. Niyibizi and J.E. Dennis, Low oxygen tension during incubation periods of chondrocyte expansion is sufficient to enhance postexpansion chondrogenesis, Tissue Eng. Part A 16 (2010), 1585-1593.
    • (2010) Tissue Eng. Part A , vol.16 , pp. 1585-1593
    • Henderson, J.H.1    Ginley, N.M.2    Caplan, A.I.3    Niyibizi, C.4    Dennis, J.E.5


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