FSH, LH, inhibin B and estradiol levels in Turner syndrome depend on age and karyotype: Longitudinal study of 70 Turner girls with or without spontaneous puberty

Human Reproduction

Volumn 25, Issue 12, 2010, Pages 3134-3141

  Hagen, Casper P ^a   Main, Katharina M ^a   Kjaergaard, Susanne ^a   Juul, Anders ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

estradiol; FSH; inhibin B; LH; Turner syndrome

Indexed keywords

ESTRADIOL; FOLLITROPIN; INHIBIN B; LUTEINIZING HORMONE;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; FEMALE; GROUPS BY AGE; HUMAN; HYPOPHYSIS GONAD SYSTEM; INFANT; KARYOTYPE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; OVARY FUNCTION; OVARY INSUFFICIENCY; PRESCHOOL CHILD; PUBERTY; SCHOOL CHILD; TURNER SYNDROME;

EID: 78649493846     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deq291     Document Type: Article

References (29)

1. Aksglaede L, Sorensen K, Petersen JH, Skakkebaek NE, Juul A. Recent decline in age at breast development: the Copenhagen Puberty Study. Pediatrics 2009;123:e932-e939.
2. Beitins IZ, Padmanabhan V. Bioactivity of gonadotropins. Endocrinol Metab Clin North Am 1991;20:85-120.
3. Chada M, Prusa R, Bronsky J, Pechova M, Kotaska K, Lisa L. Inhibin B, follicle stimulating hormone, luteinizing hormone, and estradiol and their relationship to the regulation of follicle development in girls during childhood and puberty. Physiol Res 2003;52:341-346.
4. Chellakooty M, Schmidt IM, Haavisto AM, Boisen KA, Damgaard IN, Mau C, Petersen JH, Juul A, Skakkebaek NE, Main KM. Inhibin A, inhibin B, follicle-stimulating hormone, luteinizing hormone, estradiol, and sex hormone-binding globulin levels in 473 healthy infant girls. J Clin Endocrinol Metab 2003;88:3515-3520.
5. Chrysis D, Spiliotis BE, Stene M, Cacciari E, Davenport ML. Gonadotropin secretion in girls with Turner syndrome measured by an ultrasensitive immunochemiluminometric assay. Horm Res 2006;65:261-266.
6. Conte FA, Grumbach MM, Kaplan SL. A diphasic pattern of gonadotropin secretion in patients with the syndrome of gonadal dysgenesis. J Clin Endocrinol Metab 1975;40:670-674.
7. Danforth DR, Arbogast LK, Mroueh J, Kim MH, Kennard EA, Seifer DB, Friedman CI. Dimeric inhibin: a direct marker of ovarian aging. Fertil Steril 1998;70:119-123.
8. de Roux N, Genin E, Carel JC, Matsuda F, Chaussain JL, Milgrom E. Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc Natl Acad Sci USA 2003; 100:10972-10976.
9. El Majdoubi M, Sahu A, Ramaswamy S, Plant TM. Neuropeptide Y: a hypothalamic brake restraining the onset of puberty in primates. Proc Natl Acad Sci USA 2000;97:6179-6184.
10. Fechner PY, Davenport ML, Qualy RL, Ross JL, Gunther DF, Eugster EA, Huseman C, Zagar AJ, Quigley CA. Differences in follicle-stimulating hormone secretion between 45,X monosomy Turner syndrome and 45,X/46,XX mosaicism are evident at an early age. J Clin Endocrinol Metab 2006;91:4896-4902.
11. Gravholt CH, Naeraa RW, Andersson AM, Christiansen JS, Skakkebaek NE. Inhibin A and B in adolescents and young adults with Turner's syndrome and no sign of spontaneous puberty. Hum Reprod 2002;17:2049-2053.
12. Hagen CP, Aksglaede L, Sorensen K, Main KM, Boas M, Cleemann L, Holm K, Gravholt CH, Andersson AM, Pedersen AT et al. Serum levels of anti-mullerian hormone as a marker of ovarian function in 926 healthy females from birth to adulthood and in 172 Turner syndrome patients. J Clin Endocrinol Metab 2010. (18 August 2010, Epub ahead of print). doi:10.1210/jc.2010-0930.
13. Heinrichs C, Bourdoux P, Saussez C, Vis HL, Bourguignon JP. Blood spot follicle-stimulating hormone during early postnatal life in normal girls and Turner's syndrome. J Clin Endocrinol Metab 1994;78:978-981.
14. Hreinsson JG, Otala M, Fridstrom M, Borgstrom B, Rasmussen C, Lundqvist M, Tuuri T, Simberg N, Mikkola M, Dunkel L et al. Follicles are found in the ovaries of adolescent girls with Turner's syndrome. J Clin Endocrinol Metab 2002;87:3618-3623.
15. Martin DD, Schweizer R, Schwarze CP, Elmlinger MW, Ranke MB, Binder G. The early dehydroepiandrosterone sulfate rise of adrenarche and the delay of pubarche indicate primary ovarian failure in Turner syndrome. J Clin Endocrinol Metab 2004;89:1164-1168.
16. Mitsushima D, Hei DL, Terasawa E. gamma-Aminobutyric acid is an inhibitory neurotransmitter restricting the release of luteinizing hormone-releasing hormone before the onset of puberty. Proc Natl Acad Sci USA 1994;91:395-399.
17. Mitsushima D, Marzban F, Luchansky LL, Burich AJ, Keen KL, Durning M, Golos TG, Terasawa E. Role of glutamic acid decarboxylase in the prepubertal inhibition of the luteinizing hormone releasing hormone release in female rhesus monkeys. J Neurosci 1996;16:2563-2573.
18. Mortensen KH, Rohde MD, Uldbjerg N, Gravholt CH. Repeated spontaneous pregnancies in 45, X Turner syndrome. Obstet Gynecol 2010;446-449.
19. Nielsen J, Wohlert M. Chromosome abnormalities found among 34,910 newborn children: results from a 13-year incidence study in Arhus, Denmark. Hum Genet 1991;87:81-83.
20. Ogata T, Muroya K, Matsuo N, Shinohara O, Yorifuji T, Nishi Y, Hasegawa Y, Horikawa R, Tachibana K. Turner syndrome and Xp deletions: clinical and molecular studies in 47 patients. J Clin Endocrinol Metab 2001;86:5498-5508.
21. Pasquino AM, Passeri F, Pucarelli I, Segni M, Municchi G. Spontaneous pubertal development in Turner's syndrome. Italian Study Group for Turner's syndrome. J Clin Endocrinol Metab 1997; 82:1810-1813.
22. Pohl CR, deRidder CM, Plant TM. Gonadal and nongonadal mechanisms contribute to the prepubertal hiatus in gonadotropin secretion in the female rhesus monkey (Macaca mulatta). J Clin Endocrinol Metab 1995; 80:2094-2101.
23. Reynaud K, Cortvrindt R, Verlinde F, De Schepper J, Bourgain C, Smitz J. Number of ovarian follicles in human fetuses with the 45,X karyotype. Fertil Steril 2004;81:1112-1119.
24. Sehested A, Juul AA, Andersson AM, Petersen JH, Jensen TK, Muller J, Skakkebaek NE. Serum inhibin A and inhibin B in healthy prepubertal, pubertal, and adolescent girls and adult women: relation to age, stage of puberty, menstrual cycle, follicle-stimulating hormone, luteinizing hormone, and estradiol levels. J Clin Endocrinol Metab 2000; 85:1634-1640.
25. Seminara SB, Messager S, Chatzidaki EE, Thresher RR, Acierno JS Jr, Shagoury JK, Bo-Abbas Y, Kuohung W, Schwinof KM, Hendrick AG et al. The GPR54 gene as a regulator of puberty. N Engl J Med 2003; 349:1614-1627.
26. Singh RP, Carr DH. The anatomy and histology of XO human embryos and fetuses. Anat Rec 1966;155:369-383.
27. Tanner JM. Growth at Adolescence. Oxford: Blackwell & Mott Ltd, 1962. Weiss L. Additional evidence of gradual loss of germ cells in the pathogenesis of streak ovaries in Turner's syndrome. J Med Genet 1971;8:540-544.
28. Wilson CA, Heinrichs C, Larmore KA, Craen M, Brown-Dawson J, Shaywitz S, Ross J, Klein KO. Estradiol levels in girls with Turner's syndrome compared to normal prepubertal girls as determined by an ultrasensitive assay. J Pediatr Endocrinol Metab 2003a;16:91-96.
29. Wilson ME, Fisher J, Chikazawa K, Yoda R, Legendre A, Mook D, Gould KG. Leptin administration increases nocturnal concentrations of luteinizing hormone and growth hormone in juvenile female rhesus monkeys. J Clin Endocrinol Metab 2003b;88:4874-4883.