Distinct pharmacodynamics of insulin glargine and insulin detemir: Crossover comparison in Type 1 and Type 2 diabetic patients on basal-bolus regimen

Diabetes Research and Clinical Practice

Volumn 90, Issue 3, 2010, Pages

  Kato, Tomoko ^a   Tokubuchi, Ichiro ^a   Muraishi, Kazuhisa ^a   Sato, Shuichi ^a   Kato, Tamotsu ^a   Hara, Kento ^a   Tanaka, Kayo ^a   Kaku, Hiroo ^a   Tajiri, Yuji ^a   Yamada, Kentaro ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Blood glucose; Crossover study; Insulin detemir; Insulin glargine; Insulin lispro; Pharmacodynamics

Indexed keywords

GLUCOSE; INSULIN DETEMIR; INSULIN GLARGINE; INSULIN LISPRO;

ADULT; ARTICLE; CALORIC RESTRICTION; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIABETIC PATIENT; DRUG EFFICACY; EVENING DOSAGE; FEMALE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PHARMACODYNAMICS;

ADULT; AGED; BLOOD GLUCOSE; CROSS-OVER STUDIES; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MIDDLE AGED; POSTPRANDIAL PERIOD;

EID: 78649484228     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2010.08.011     Document Type: Article

References (4)

1. Barnett A.H. A review of basal insulins. Diabet Med 2003, 20:873-885.
2. Gough S.C. A review of human and analogue insulin trials. Diabetes Res Clin Pract 2007, 77:1-15.
3. Porcellati F., Rossetti P., Busciantella N.R., Marzotti S., Lucidi P., Luzio S., et al. Comparison of pharmacokinetics and dynamics of the long-acting insulin analogs glargine and detemir at steady state in type 1 diabetes: a double-blind, randomized, crossover study. Diabetes Care 2007, 30:2447-2452.
4. King A.B. Once-daily insulin detemir is comparable to once-daily insulin glargine in providing glycaemic control over 24h in patients with type 2 diabetes: a double-blind, randomized, crossover study. Diabetes Obes Metab 2009, 11:69-71.