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Volumn , Issue , 2006, Pages 961-2

Werner Syndrome as a Model of Human Aging

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EID: 78649475037     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012369391-4/50081-3     Document Type: Chapter
Times cited : (4)

References (60)
  • 1
    • 0141567744 scopus 로고    scopus 로고
    • RecQ helicases: Suppressors of tumorigenesis and premature aging
    • Bachrati C.Z., Hickson I.D. RecQ helicases: Suppressors of tumorigenesis and premature aging. Biochem. J. 2003, 374:577-606.
    • (2003) Biochem. J , vol.374 , pp. 577-606
    • Bachrati, C.Z.1    Hickson, I.D.2
  • 2
    • 0345059205 scopus 로고    scopus 로고
    • Werner syndrome and its protein: Clinical, cellular and molecular advances
    • Bohr V.A. Werner syndrome and its protein: Clinical, cellular and molecular advances. Mech. Ageing Dev. 2003, 124:1073-1082.
    • (2003) Mech. Ageing Dev , vol.124 , pp. 1073-1082
    • Bohr, V.A.1
  • 4
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • Campisi J. Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors. Cell 2005, 120:513-522.
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 5
    • 0034639302 scopus 로고    scopus 로고
    • Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and athero-sclerosis
    • Castro E., Edland S.D., Lee L., Ogburn C.E., Deeb S.S., Brown G., et al. Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and athero-sclerosis. Am. J. Med. Genet. 2000, 95:374-380.
    • (2000) Am. J. Med. Genet , vol.95 , pp. 374-380
    • Castro, E.1    Edland, S.D.2    Lee, L.3    Ogburn, C.E.4    Deeb, S.S.5    Brown, G.6
  • 6
    • 0033582750 scopus 로고    scopus 로고
    • Polymorphisms at the Werner locus: I. Newly identified polymorphisms, ethnic variability of 1367Cys/Arg, and its stability in a population of Finnish centenarians
    • Castro E., Ogburn C.E., Hunt K.E., Tilvis R., Louhija J., Penttinen R., et al. Polymorphisms at the Werner locus: I. Newly identified polymorphisms, ethnic variability of 1367Cys/Arg, and its stability in a population of Finnish centenarians. Am. J. Med. Genet. 1999, 82:399-403.
    • (1999) Am. J. Med. Genet , vol.82 , pp. 399-403
    • Castro, E.1    Ogburn, C.E.2    Hunt, K.E.3    Tilvis, R.4    Louhija, J.5    Penttinen, R.6
  • 7
    • 3543043128 scopus 로고    scopus 로고
    • Essential role of limiting telomeres in the pathogenesis of Werner syndrome
    • Chang S., Multani A.S., Cabrera N.G., Naylor M.L., Laud P., Lombard D., et al. Essential role of limiting telomeres in the pathogenesis of Werner syndrome. Nat. Genet. 2004, 36:877-882.
    • (2004) Nat. Genet , vol.36 , pp. 877-882
    • Chang, S.1    Multani, A.S.2    Cabrera, N.G.3    Naylor, M.L.4    Laud, P.5    Lombard, D.6
  • 10
    • 4544301617 scopus 로고    scopus 로고
    • Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes
    • Du X., Shen J., Kugan N., Furth E.E., Lombard D.B., Cheung C., et al. Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes. Mol. Cell Biol. 2004, 24:8437-8446.
    • (2004) Mol. Cell Biol , vol.24 , pp. 8437-8446
    • Du, X.1    Shen, J.2    Kugan, N.3    Furth, E.E.4    Lombard, D.B.5    Cheung, C.6
  • 11
    • 0013907774 scopus 로고
    • Werner's syndrome: A review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
    • Epstein C.J., Martin G.M., Schultz A.L., Motulsky A.G. Werner's syndrome: A review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine 1966, 45:177-221.
    • (1966) Medicine , vol.45 , pp. 177-221
    • Epstein, C.J.1    Martin, G.M.2    Schultz, A.L.3    Motulsky, A.G.4
  • 13
    • 0034797868 scopus 로고    scopus 로고
    • Clinical characteristics of Werner syndrome and other premature aging syndromes: Pattern of aging in progeroid syndromes
    • Goto M. Clinical characteristics of Werner syndrome and other premature aging syndromes: Pattern of aging in progeroid syndromes. Gann Monograph. Cancer Res. 2001, 49:27-39.
    • (2001) Gann Monograph. Cancer Res , vol.49 , pp. 27-39
    • Goto, M.1
  • 14
    • 0030691121 scopus 로고    scopus 로고
    • Hierarchical deterioration of body systems in Werner's syndrome: Implications for normal aging
    • Goto M. Hierarchical deterioration of body systems in Werner's syndrome: Implications for normal aging. Mech. Ageing Dev. 1997, 98:239-254.
    • (1997) Mech. Ageing Dev , vol.98 , pp. 239-254
    • Goto, M.1
  • 16
    • 0026502062 scopus 로고
    • Genetic linkage of Werner's syndrome to five markers on chromosome 8
    • Goto M., Rubenstein M., Weber J., Woods K., Drayna D. Genetic linkage of Werner's syndrome to five markers on chromosome 8. Nature 1992, 355:735-738.
    • (1992) Nature , vol.355 , pp. 735-738
    • Goto, M.1    Rubenstein, M.2    Weber, J.3    Woods, K.4    Drayna, D.5
  • 17
    • 0032848570 scopus 로고    scopus 로고
    • Immunological diagnosis of Werner syndrome by down-regulated and truncated gene products
    • Goto M., Yamabe Y., Shiratori M., Okada M., Kawabe T., Matsumoto T., et al. Immunological diagnosis of Werner syndrome by down-regulated and truncated gene products. Hum. Genet. 1999, 105:301-307.
    • (1999) Hum. Genet , vol.105 , pp. 301-307
    • Goto, M.1    Yamabe, Y.2    Shiratori, M.3    Okada, M.4    Kawabe, T.5    Matsumoto, T.6
  • 18
    • 0034793686 scopus 로고    scopus 로고
    • Dermatological features and collagen metabolism in Werner syndrome
    • Hatamochi A. Dermatological features and collagen metabolism in Werner syndrome. Gann Monograph. Cancer Res. 2001, 49:51-59.
    • (2001) Gann Monograph. Cancer Res , vol.49 , pp. 51-59
    • Hatamochi, A.1
  • 19
    • 0041736002 scopus 로고    scopus 로고
    • Drawing the line in progeria syndromes
    • Hegele R.A. Drawing the line in progeria syndromes. Lancet 2003, 362:416-417.
    • (2003) Lancet , vol.362 , pp. 416-417
    • Hegele, R.A.1
  • 20
    • 0034192355 scopus 로고    scopus 로고
    • WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts
    • Hisama F., Chen Y.-H., Meyn M.S., Oshima J., Weissman S.M. WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts. Cancer Res. 2000, 60:2372-2376.
    • (2000) Cancer Res , vol.60 , pp. 2372-2376
    • Hisama, F.1    Chen, Y.-H.2    Meyn, M.S.3    Oshima, J.4    Weissman, S.M.5
  • 23
    • 0034726966 scopus 로고    scopus 로고
    • Differential regulation of the human RecQ family helicases in cell transformation and cell cycle
    • Kawabe T., Tsuyama N., Kitao S., Nishikawa K., Shimamoto A., Shiratori M., et al. Differential regulation of the human RecQ family helicases in cell transformation and cell cycle. Oncogene 2000, 19:4764-4772.
    • (2000) Oncogene , vol.19 , pp. 4764-4772
    • Kawabe, T.1    Tsuyama, N.2    Kitao, S.3    Nishikawa, K.4    Shimamoto, A.5    Shiratori, M.6
  • 24
    • 4444281968 scopus 로고    scopus 로고
    • What can progeroid syndromes tell us about human aging?
    • Kipling D., Davis T., Ostler E.L., Faragher R.G.A. What can progeroid syndromes tell us about human aging?. Science 2004, 305:1426-1431.
    • (2004) Science , vol.305 , pp. 1426-1431
    • Kipling, D.1    Davis, T.2    Ostler, E.L.3    Faragher, R.G.A.4
  • 25
    • 0032573157 scopus 로고    scopus 로고
    • A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity
    • Lebel M., Leder P. A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity. Proc. Natl. Acad. Sci. USA 1998, 95:13097-13102.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13097-13102
    • Lebel, M.1    Leder, P.2
  • 27
    • 13944280713 scopus 로고    scopus 로고
    • Genetic modulation of senescent phenotypes in Homo sapiens
    • Martin G.M. Genetic modulation of senescent phenotypes in Homo sapiens. Cell 2005, 120:523-532.
    • (2005) Cell , vol.120 , pp. 523-532
    • Martin, G.M.1
  • 28
    • 0014816132 scopus 로고
    • Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype
    • Martin G.M., Sprague C.A., Epstein C.J. Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype. Lab. Invest. 1970, 23:86-92.
    • (1970) Lab. Invest , vol.23 , pp. 86-92
    • Martin, G.M.1    Sprague, C.A.2    Epstein, C.J.3
  • 30
    • 0030836805 scopus 로고    scopus 로고
    • Comparative sequence analysis of ribonucleases HII, III, PH, and D
    • Mian I.S. Comparative sequence analysis of ribonucleases HII, III, PH, and D. Nucleic Acids Res. 1997, 25:3187-3195.
    • (1997) Nucleic Acids Res , vol.25 , pp. 3187-3195
    • Mian, I.S.1
  • 31
    • 4444327055 scopus 로고    scopus 로고
    • "Accelerated aging": A primrose path to insight?
    • Miller R.A. "Accelerated aging": A primrose path to insight?. Aging Cell 2004, 3:47-51.
    • (2004) Aging Cell , vol.3 , pp. 47-51
    • Miller, R.A.1
  • 33
    • 0034798464 scopus 로고    scopus 로고
    • Cancer pathogenesis in the human RecQ helicase deficiency syndromes
    • Monnat R.J. Cancer pathogenesis in the human RecQ helicase deficiency syndromes. Gann Monograph Cancer Res. 2001, 49:83-94.
    • (2001) Gann Monograph Cancer Res. , vol.49 , pp. 83-94
    • Monnat, R.J.1
  • 35
    • 0034194139 scopus 로고    scopus 로고
    • Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes
    • Moser M.J., Bigbee W.L., Grant S.G., Emond M.J., Langlois R.G., Jensen R.H., et al. Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes. Cancer Res. 2000, 60:2492-2496.
    • (2000) Cancer Res , vol.60 , pp. 2492-2496
    • Moser, M.J.1    Bigbee, W.L.2    Grant, S.G.3    Emond, M.J.4    Langlois, R.G.5    Jensen, R.H.6
  • 38
    • 0030915681 scopus 로고    scopus 로고
    • Positionally cloned human disease genes: Patterns of evolutionarily conservation and functional motifs
    • Mushegian A.R., Bassett D.E., Boguski M.S., Bork P., Koonin E.V. Positionally cloned human disease genes: Patterns of evolutionarily conservation and functional motifs. Proc. Natl. Acad. Sci. USA 1997, 94:5831-5836.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5831-5836
    • Mushegian, A.R.1    Bassett, D.E.2    Boguski, M.S.3    Bork, P.4    Koonin, E.V.5
  • 39
    • 0031453968 scopus 로고    scopus 로고
    • An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants
    • Ogburn C.E., Oshima J., Poot M., Chen R., Hunt K.E., Gollahon K.A., et al. An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants. Hum. Genet. 1997, 101:121-125.
    • (1997) Hum. Genet , vol.101 , pp. 121-125
    • Ogburn, C.E.1    Oshima, J.2    Poot, M.3    Chen, R.4    Hunt, K.E.5    Gollahon, K.A.6
  • 40
    • 0001225459 scopus 로고    scopus 로고
    • Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients
    • Okada M., Goto M., Furuichi Y., Sugimoto M. Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients. Biol. Pharm. Bull. 1998, 21:235-239.
    • (1998) Biol. Pharm. Bull , vol.21 , pp. 235-239
    • Okada, M.1    Goto, M.2    Furuichi, Y.3    Sugimoto, M.4
  • 41
    • 0001026233 scopus 로고
    • Werner's syndrome-a heredo-familial disorder with scleroderma, bilateral juvenile cataract, precocious graying of hair and endocrine stigmatization
    • Oppenheimer B.S., Kugel V.H. Werner's syndrome-a heredo-familial disorder with scleroderma, bilateral juvenile cataract, precocious graying of hair and endocrine stigmatization. Trans. Assoc. Amer. Physicians 1934, 49:358-370.
    • (1934) Trans. Assoc. Amer. Physicians , vol.49 , pp. 358-370
    • Oppenheimer, B.S.1    Kugel, V.H.2
  • 42
    • 2442531966 scopus 로고    scopus 로고
    • Junction of RecQ helicase biochemistry and human disease
    • Opresko P.L., Cheng W.-H., Bohr V.A. Junction of RecQ helicase biochemistry and human disease. J. Biol. Chem. 2004, 279:18099-18102.
    • (2004) J. Biol. Chem , vol.279 , pp. 18099-18102
    • Opresko, P.L.1    Cheng, W.-H.2    Bohr, V.A.3
  • 43
    • 2942637828 scopus 로고    scopus 로고
    • The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2
    • Opresko P.L., Otterlei M., Graakjaer J., Bruheim P., Dawut L., Kolvraa S., et al. The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2. Mol. Cell 2004, 14:763-764.
    • (2004) Mol. Cell , vol.14 , pp. 763-764
    • Opresko, P.L.1    Otterlei, M.2    Graakjaer, J.3    Bruheim, P.4    Dawut, L.5    Kolvraa, S.6
  • 44
    • 84882901827 scopus 로고    scopus 로고
    • Memory of my father, Otto Werner
    • Pehmoeller G. Memory of my father, Otto Werner. Gann Monograph Cancer Res. 2001, 49:vii-viii.
    • (2001) Gann Monograph Cancer Res , vol.49 , pp. 7-8
    • Pehmoeller, G.1
  • 46
    • 0035871341 scopus 로고    scopus 로고
    • Loss of Werner syndrome protein function promotes aberrant mitotic recombination
    • Prince P.R., Emond M.J., Monnat R.J. Loss of Werner syndrome protein function promotes aberrant mitotic recombination. Genes Dev. 2001, 15:933-938.
    • (2001) Genes Dev , vol.15 , pp. 933-938
    • Prince, P.R.1    Emond, M.J.2    Monnat, R.J.3
  • 47
    • 0032808411 scopus 로고    scopus 로고
    • Cell fusion corrects the 4-nitroquinoline 1-oxide sensitivity of Werner syndrome fibroblast cell lines
    • Prince P.R., Ogburn C.E., Moser M.J., Emond M.J., Martin G.M., Monnat R.J. Cell fusion corrects the 4-nitroquinoline 1-oxide sensitivity of Werner syndrome fibroblast cell lines. Hum. Genet. 1999, 105:132-138.
    • (1999) Hum. Genet , vol.105 , pp. 132-138
    • Prince, P.R.1    Ogburn, C.E.2    Moser, M.J.3    Emond, M.J.4    Martin, G.M.5    Monnat, R.J.6
  • 49
    • 0020455613 scopus 로고
    • Werner syndrome: A review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations
    • Salk D. Werner syndrome: A review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations. Human Genetics 1982, 62:1-15.
    • (1982) Human Genetics , vol.62 , pp. 1-15
    • Salk, D.1
  • 50
    • 0003128111 scopus 로고
    • Werner's Syndrome and Human Aging
    • Plenum Press, New York, D. Salk, Y. Fujiwara, G.M. Martin (Eds.)
    • Werner's Syndrome and Human Aging. Advances in Experimental Medicine and Biology 1985, Plenum Press, New York. D. Salk, Y. Fujiwara, G.M. Martin (Eds.).
    • (1985) Advances in Experimental Medicine and Biology
  • 52
    • 1842685207 scopus 로고    scopus 로고
    • The Werner syndrome protein has separable recombination and viability functions
    • Swanson C., Saintigny Y., Emond M.J., Monnat R.J. The Werner syndrome protein has separable recombination and viability functions. DNA Repair 2004, 3:1-10.
    • (2004) DNA Repair , vol.3 , pp. 1-10
    • Swanson, C.1    Saintigny, Y.2    Emond, M.J.3    Monnat, R.J.4
  • 53
    • 0001078903 scopus 로고
    • Werner's syndrome (progeria of the adult) and Rothmund's syndrome: Two types of closely related hederofamilial atrophic dermatoses with juvenile cataracts and endocrine features: a critical study of five new cases
    • Thannhauser S.J. Werner's syndrome (progeria of the adult) and Rothmund's syndrome: Two types of closely related hederofamilial atrophic dermatoses with juvenile cataracts and endocrine features: a critical study of five new cases. Ann. Intern. Med. 1945, 23:559-626.
    • (1945) Ann. Intern. Med , vol.23 , pp. 559-626
    • Thannhauser, S.J.1
  • 54
    • 0035796042 scopus 로고    scopus 로고
    • Homologous recombinational repair of DNA ensures mammalian chromosome stability
    • Thompson L.H., Schild D. Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutat. Res. 2001, 477:131-153.
    • (2001) Mutat. Res , vol.477 , pp. 131-153
    • Thompson, L.H.1    Schild, D.2
  • 55
    • 0021171248 scopus 로고
    • Werner's syndrome: An underdiagnosed disorder resembling premature aging
    • Tollefsbol T.O., Cohen H.J. Werner's syndrome: An underdiagnosed disorder resembling premature aging. Age 1984, 7:75-88.
    • (1984) Age , vol.7 , pp. 75-88
    • Tollefsbol, T.O.1    Cohen, H.J.2
  • 56
    • 0033978881 scopus 로고    scopus 로고
    • Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene
    • Wang L., Ogburn C.E., Ware C.B., Ladiges W.C., Youssoufian H., Martin G.M., et al. Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene. Genetics 2000, 154:357-362.
    • (2000) Genetics , vol.154 , pp. 357-362
    • Wang, L.1    Ogburn, C.E.2    Ware, C.B.3    Ladiges, W.C.4    Youssoufian, H.5    Martin, G.M.6
  • 57
    • 0004183888 scopus 로고
    • On cataract in conjunction with scleroderma (translated by H. Hoehn)
    • Advances in Experimental Medicine and Biology Plenum Press, New York, D. Salk, Y. Fujiwara, G.M. Martin (Eds.)
    • Werner O. On cataract in conjunction with scleroderma (translated by H. Hoehn). Werner's Syndrome and Human Aging, Vol. 190, Advances in Experimental Medicine and Biology 1985, 1-14. Plenum Press, New York. D. Salk, Y. Fujiwara, G.M. Martin (Eds.).
    • (1985) Werner's Syndrome and Human Aging , vol.190 , pp. 1-14
    • Werner, O.1
  • 59
    • 17344379792 scopus 로고    scopus 로고
    • Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population
    • Ye L., Miki T., Nakura J., Oshima J., Kamino K., Rakugi H., et al. Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population. Am. J. Hum. Genet. 1997, 68:494-498.
    • (1997) Am. J. Hum. Genet , vol.68 , pp. 494-498
    • Ye, L.1    Miki, T.2    Nakura, J.3    Oshima, J.4    Kamino, K.5    Rakugi, H.6


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