Exposure of neonatal female rats to bisphenol A disrupts hypothalamic LHRH pre-mRNA processing and estrogen receptor alpha expression in nuclei controlling estrous cyclicity

Reproductive Toxicology

Volumn 30, Issue 4, 2010, Pages 625-634

  Monje, L ^a   Varayoud, J ^a   Munoz de Toro M ^a   Luque, E H ^a   Ramos, J G ^a  

^a UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

Author keywords

Bisphenol A; Hypothalamus; LHRH pre mRNA

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ENDOCRINE DISRUPTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GONADORELIN; LUTEINIZING HORMONE; MESSENGER RNA PRECURSOR; PROGESTERONE RECEPTOR; STEROID RECEPTOR COACTIVATOR 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BRAIN NERVE CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; ESTRUS CYCLE; FEMALE; GENE EXPRESSION; HYPOTHALAMUS; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; IMMUNOHISTOCHEMISTRY; INTRON; LUTEINIZING HORMONE BLOOD LEVEL; MALE; NEWBORN; NONHUMAN; PERINATAL DRUG EXPOSURE; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROCESSING; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; ESTROGEN RECEPTOR ALPHA; ESTROUS CYCLE; FEMALE; GONADOTROPIN-RELEASING HORMONE; HYPOTHALAMUS; INTRONS; LUTEINIZING HORMONE; NERVE NET; NERVE TISSUE PROTEINS; NEURONS; ORGAN SPECIFICITY; PHENOLS; RATS; RATS, WISTAR; RNA PRECURSORS; RNA, MESSENGER;

RATTUS;

EID: 78649461891     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2010.08.004     Document Type: Article

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