A Novel 18-Norclerodane diterpenoid from the roots of tinospora sagittata var. yunnanensis

Molecules

Volumn 15, Issue 11, 2010, Pages 8360-8365

  Huang, Xiang Zhong ^a   Cheng, Chun Mei ^a   Dai, Yun ^a   Fu, Guang Miao ^b   Guo, Jun Ming ^a   Yin, Yan ^a   Liang, Hui ^a  

^a YUNNAN MINZU UNIVERSITY   (China)

^b HENAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Clerodane diterpenoid; Cytotoxic activity; Sagitone; Tinospora sagittata var. Yunnanensis

Indexed keywords

ANTINEOPLASTIC AGENT; CLERODANE DERIVATIVE;

ARTICLE; CELL STRAIN HL 60; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; TINOSPORA; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DITERPENES, CLERODANE; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PLANT ROOTS; TINOSPORA;

EID: 78649452794     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15118360     Document Type: Article

References (10)

1. Hanson, J.R. Diterpenoids. Nat. Prod. Rep. 2007, 24, 1332-1341.
2. Castro, A.; Coll, J. Neo-clerodane diterpenoids from Verbenaceae: Structural elucidation and biological activity. Nat. Prod. Commun. 2008, 3, 1021-1031.
3. Coll, J.; Tandron, Y.A. Neo-clerodane diterpenoids from Ajuga: Structural elucidation and biological activity. Phytochem. Rev. 2007, 7, 25-49.
4. Kabouche, A.; Kabouche, Z. Bioactive diterpenoids of Salvia species. Stud. Nat. Prod. Chem. 2008, 35, 753-834.
5. Maurya, R.; Wazir, V.; Kapil, R.S. Biotherapeutic diterpene glucosides from Tinospora species. J. Indian Chem. Soc. 1994, 71, 361-364.
6. Pathak, S.K.; Jain, D.C.; Sharma, R.P. Chemistry and biological activities of the Genera Tinospora. Pharm. Biol. 1995, 33, 277-287.
7. Jiangsu New Medical College. The Dictionary of Traditional Chinese Medicine; People's Publishing House: Shanghai, China, 1986; pp. 1393-1394.
8. Cheng, C.M.; Dai, Y.; Huang, X.Z.; Zhu, Y.; Dai, J.H.; Liu, X.F.; Wang, J. Chemical constituents from roots of Tinospora sagittata var. yunnanensis. Chin. Tradit. Herb. Drug. 2010, 41, 689-692.
9. Song, C.Q.; Xu, R.S. New clerodane diterpenoids from Tinospora capillipes. Chin. Chem. Lett. 1992, 3, 185-188.
10. Fu, G.M.; Wang, Y.H.; Gao, S.; Tang, M.H.; Yu, S.S. Five new cytotoxic triterpenoid saponins from the roots of Symplocos chinensis. Planta Med. 2005, 71, 666-672.