The healing of full-thickness burns treated by using plasmid DNA encoding VEGF-165 activated collagen-chitosan dermal equivalents

Biomaterials

Volumn 32, Issue 4, 2011, Pages 1019-1031

  Guo, Rui ^a   Xu, Shaojun ^b   Ma, Lie ^a   Huang, Aibin ^a   Gao, Changyou ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Angiogenesis; Collagen chitosan scaffold; Full thickness burns; Gene therapy; Vascular endothelial growth factor (VEGF)

Indexed keywords

ANGIOGENESIS; BI-LAYER; CHITOSAN SCAFFOLD; DEEP BURN; DERMAL EQUIVALENT; DERMAL REGENERATION; EXPERIMENTAL GROUPS; FULL-THICKNESS BURNS; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; IN-VITRO; INCUBATION TIME; N , N , N-TRIMETHYL CHITOSAN CHLORIDE; NORMAL SKIN; PLASMID DNA; PROTEIN LEVEL; SKIN GRAFTING; SUPERCOILED; ULTRA-THIN; VASCULAR ENDOTHELIAL GROWTH FACTOR; WESTERN BLOTTING;

BLOOD VESSELS; CHITIN; CHITOSAN; CHLORINE COMPOUNDS; COLLAGEN; DNA; ENCODING (SYMBOLS); ENDOTHELIAL CELLS; GENE THERAPY; GENETIC ENGINEERING; MICROBIOLOGY; PEPTIDES; POLYMERASE CHAIN REACTION; SELF ASSEMBLY; TENSILE STRENGTH;

SCAFFOLDS;

ALPHA SMOOTH MUSCLE ACTIN; BIOMATERIAL; CD31 ANTIGEN; CHITOSAN DERIVATIVE; COLLAGEN DERIVATIVE; ENHANCED GREEN FLUORESCENT PROTEIN; MESSENGER RNA; NAKED DNA; PLASMID DNA; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL GROWTH FACTOR 165 PLUS N,N,N TRIMETHYL CHITOSAN CHLORIDE COMPLEX; VASCULOTROPIN; VASCULOTROPIN 165;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILAYER MEMBRANE; BURN; CELL VIABILITY; CONTROLLED STUDY; DNA STRAND; DNA TRANSFER; ENDOTHELIUM CELL; GRAFT SURVIVAL; HUMAN; HUMAN CELL; IN VITRO STUDY; MINIPIG; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SKIN GRAFT; SKIN TRANSPLANTATION; TENSILE STRENGTH; TISSUE REGENERATION; UMBILICAL VEIN; WESTERN BLOTTING; WOUND HEALING;

ANIMALS; BIOCOMPATIBLE MATERIALS; BURNS; CELLS, CULTURED; CHITOSAN; COLLAGEN; DERMIS; ENDOTHELIAL CELLS; HUMANS; MATERIALS TESTING; PLASMIDS; REGENERATION; SKIN TRANSPLANTATION; SKIN, ARTIFICIAL; SWINE; TENSILE STRENGTH; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

SUS;

EID: 78649450178     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.087     Document Type: Article

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