Curative effects of hydrogen sulfide against acetaminophen-induced hepatotoxicity in mice

Life Sciences

Volumn 87, Issue 23-26, 2010, Pages 692-698

  Morsy, Mohamed A ^a   Ibrahim, Salwa A ^a   Abdelwahab, Soha A ^a   Zedan, Mervat Z ^a   Elbitar, Hussien I ^b  

^a Minia University   (Egypt)

^b Assiut University Faculty of Medicine   (Egypt)

Author keywords

Acetaminophen; Anti inflammatory; Anti oxidative; Hepatotoxicity; Hydrogen sulfide

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ALANINE AMINOTRANSFERASE; CATALASE; CYCLOOXYGENASE 2; GLIBENCLAMIDE; GLUTATHIONE; HYDROGEN SULFIDE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; NITRIC OXIDE; PARACETAMOL; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOPATHOLOGIC SKIN REACTION; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SWISS WEBSTER MOUSE; THERAPY EFFECT;

ACETAMINOPHEN; ACETYLCYSTEINE; ALANINE TRANSAMINASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIDOTES; ANTIOXIDANTS; CYCLOOXYGENASE 2; DRUG-INDUCED LIVER INJURY; GLUTATHIONE; HEPATOCYTES; HYDROGEN SULFIDE; MALE; MALONDIALDEHYDE; MICE; NITRIC OXIDE; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 78649449573     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.10.004     Document Type: Article

References (41)

1. Bhave V.S., Donthamsetty S., Latendresse J.R., Muskhelishvili L., Mehendale H.M. Secretory phospholipase A2 mediates progression of acute liver injury in the absence of sufficient cyclooxygenase-2. Toxicol Appl Pharmacol 2008, 228(2):225-238.
2. Buege J.A., Aust S.D. Microsomal lipid peroxidation. Meth Enzymol 1978, 52:302-310.
3. Casado M., Callejas N.A., Rodrigo J., Zhao X., Dey S.K., Boscá L., et al. Contribution of cyclooxygenase 2 to liver regeneration after partial hepatectomy. FASEB J 2001, 15(11):2016-2018.
4. Chen Y.H., Wu R., Geng B., Qi Y.F., Wang P.P., Yao W.Z., et al. Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma. Cytokine 2009, 45(2):117-123.
5. Coffey R.J., Hawkey C.J., Damstrup L., Graves-Deal R., Daniel V.C., Dempsey P.J., et al. Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells. Proc Natl Acad Sci USA 1997, 94(2):657-662.
6. Dhaese I., Van Colen I., Lefebvre R.A. Mechanisms of action of hydrogen sulfide in relaxation of mouse distal colonic smooth muscle. Eur J Pharmacol 2010, 628(1-3):179-186.
7. Elrod J.W., Calvert J.W., Morrison J., Doeller J.E., Kraus D.W., Tao L., et al. Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proc Natl Acad Sci USA 2007, 104(39):15560-15565.
8. Faller S., Ryter S.W., Choi A.M., Loop T., Schmidt R., Hoetzel A. Inhaled hydrogen sulfide protects against ventilator-induced lung injury. Anesthesiology 2010, 113(1):104-115.
9. Fontana R.J. Acute liver failure including acetaminophen overdose. Med Clin North Am 2008, 92(4):761-794.
10. Fu Z., Liu X., Geng B., Fang L., Tang C. Hydrogen sulfide protects rat lung from ischemia-reperfusion injury. Life Sci 2008, 82(23-24):1196-1202.
11. Geng B., Chang L., Pan C., Qi Y., Zhao J., Pang Y., et al. Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol. Biochem Biophys Res Commun 2004, 318(3):756-763.
12. Gong Q.H., Wang Q., Pan L.L., Liu X.H., Huang H., Zhu Y.Z. Hydrogen sulfide attenuates lipopolysaccharide-induced cognitive impairment: a pro-inflammatory pathway in rats. Pharmacol Biochem Behav 2010, 96(1):52-58.
13. Hu L.F., Lu M., Tiong C.X., Dawe G.S., Hu G., Bian J.S. Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models. Aging Cell 2010, 9(2):135-146.
14. Hu L.F., Pan T.T., Neo K.L., Yong Q.C., Bian J.S. Cyclooxygenase-2 mediates the delayed cardioprotection induced by hydrogen sulfide preconditioning in isolated rat cardiomyocytes. Pfluegers Arch 2008, 455(6):971-978.
15. Jaeschke H., Bajt M.L. Intracellular signaling mechanisms of acetaminophen-induced liver cell death. Toxicol Sci 2006, 89(1):31-41.
16. James L.P., Mayeux P.R., Hinson J.A. Acetaminophen-induced hepatotoxicity. Drug Metab Dispos 2003, 31(12):1499-1506.
17. Jha S., Calvert J.W., Duranski M.R., Ramachandran A., Lefer D.J. Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling. Am J Physiol Heart Circ Physiol 2008, 295(2):H801-H806.
18. Kang K., Zhao M., Jiang H., Tan G., Pan S., Sun X. Role of hydrogen sulfide in hepatic ischemia-reperfusion-induced injury in rats. Liver Transplant 2009, 15(10):1306-1314.
19. Kimura Y., Goto Y., Kimura H. Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria. Antioxid Redox Signal 2010, 12(1):1-13.
20. Kubo S., Kurokawa Y., Doe I., Masuko T., Sekiguchi F., Kawabata A. Hydrogen sulfide inhibits activity of three isoforms of recombinant nitric oxide synthase. Toxicology 2007, 241(1-2):92-97.
21. Lee H.T., Emala C.W. Protein kinase C and G(i/o) proteins are involved in adenosine- and ischemic preconditioning-mediated renal protection. J Am Soc Nephrol 2001, 12(2):233-240.
22. Li G., Han C., Xu L., Lim K., Isse K., Wu T. Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor. Hepatology 2009, 50(30):834-843.
23. Medeiros J.V., Bezerra V.H., Gomes A.S., Barbosa A.L., Lima-Júnior R.C., Soares P.M., et al. Hydrogen sulfide prevents ethanol-induced gastric damage in mice: role of ATP-sensitive potassium channels and capsaicin-sensitive primary afferent neurons. J Pharmacol Exp Ther 2009, 330(3):764-770.
24. Oh G.S., Pae H.O., Lee B.S., Kim B.N., Kim J.M., Kim H.R., et al. Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Free Radic Biol Med 2006, 41(1):106-119.
25. Oz H.S., McClain C.J., Nagasawa H.T., Ray M.B., de Villiers W.J., Chen T.S. Diverse antioxidants protect against acetaminophen hepatotoxicity. J Biochem Mol Toxicol 2004, 18(6):361-368.
26. Reilly T.P., Brady J.N., Marchick M.R., Bourdi M., George J.W., Radonovich M.F., et al. A protective role for cyclooxygenase-2 in drug-induced liver injury in mice. Chem Res Toxicol 2001, 14(12):1620-1628.
27. Sandilands E.A., Bateman D.N. Adverse reactions associated with acetylcysteine. Clin Toxicol (Philadelphia) 2009, 47(2):81-88.
28. Sastry K.V., Moudgal R.P., Mohan J., Tyagi J.S., Rao G.S. Spectrophotometric determination of serum nitrite and nitrate by copper-cadmium alloy. Anal Biochem 2002, 306(1):79-82.
29. Schnellmann J.G., Pumford N.R., Kusewitt D.F., Bucci T.J., Hinson J.A. Deferoxamine delays the development of the hepatotoxicity of acetaminophen in mice. Toxicol Lett 1999, 106(1):79-88.
30. Sivarajah A., McDonald M.C., Thiemermann C. The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. Shock 2006, 26(2):154-161.
31. Tamizhselvi R., Koh Y.H., Sun J., Zhang H., Bhatia M. Hydrogen sulfide induces ICAM-1 expression and neutrophil adhesion to caerulein-treated pancreatic acinar cells through NF-kappaB and Src-family kinases pathway. Exp Cell Res 2010, 316(9):1625-1636.
32. Toklu H.Z., Sehirli A.O., Velioǧlu-OAcetaminophen-induced toxicity is prevented by beta-d-glucan treatment in ünç A., Cetinel S., Sener G. Acetaminophen-induced toxicity is prevented by beta-d-glucan treatment in mice. Eur J Pharmacol 2006, 543(1-3):133-140.
33. Wagner C.A. Hydrogen sulfide: a new gaseous signal molecule and blood pressure regulator. J Nephrol 2009, 22:173-176.
34. Whiteman M., Armstrong J.S., Chu S.H., Jia-Ling S., Wong B.S., Cheung N.S., et al. The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'?. J Neurochem 2004, 90(3):765-768.
35. Whiteman M., Li L., Kostetski I., Chu S.H., Siau J.L., Bhatia M., et al. Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide. Biochem Biophys Res Commun 2006, 343(1):303-310.
36. Yin H., Cheng L., Langenbach R., Ju C. Prostaglandin I(2) and E(2) mediate the protective effects of cyclooxygenase-2 in a mouse model of immune-mediated liver injury. Hepatology 2007, 45(1):159-169.
37. Yonezawa D., Sekiguchi F., Miyamoto M., Taniguchi E., Honjo M., Masuko T., et al. A protective role of hydrogen sulfide against oxidative stress in rat gastric mucosal epithelium. Toxicology 2007, 241(1-2):11-18.
38. Zhang J, Sio SW, Moochhala S, Bhatia M. Role of hydrogen sulfide in severe burn injury-induced inflammation in the mouse. Mol Med 2010;16(9-10):417-24.
39. Zhang L.M., Jiang C.X., Liu D.W. Hydrogen sulfide attenuates neuronal injury induced by vascular dementia via inhibiting apoptosis in rats. Neurochem Res 2009, 34(11):1984-1992.
40. Zhong G., Chen F., Cheng Y., Tang C., Du J. The role of hydrogen sulfide generation in the pathogenesis of hypertension in rats induced by inhibition of nitric oxide synthase. J Hypertens 2003, 21(10):1879-1885.
41. Zhong G.Z., Li Y.B., Liu X.L., Guo L.S., Chen M.L., Yang X.C. Hydrogen sulfide opens the KATP channel on rat atrial and ventricular myocytes. Cardiology 2010, 115:120-126.