Evaluation of analgesic efficacy, gastrotoxicity and nephrotoxicity of fixed-dose combinations of nonselective, preferential and selective cyclooxgenase inhibitors with paracetamol in rats

Experimental and Toxicologic Pathology

Volumn 62, Issue 6, 2010, Pages 653-662

  Kumar, Gaurav ^a   Hota, Debasish ^a   Nahar Saikia, Uma ^a   Pandhi, Promila ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Analgesic efficacy; Fixed dose combinations; Gastrotoxicity; Nephrotoxicity; Nonsteroidal anti inflammatory drugs (NSAIDs)

Indexed keywords

CELECOXIB; IBUPROFEN; MELOXICAM; PARACETAMOL; STOMACH MUCIN;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; GASTROINTESTINAL TOXICITY; HISTOPATHOLOGY; MALE; MONOTHERAPY; NEPHROTOXICITY; NONHUMAN; PAIN; RAT; TAIL FLICK TEST;

ACETAMINOPHEN; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOOXYGENASE INHIBITORS; DRUG THERAPY, COMBINATION; FEMALE; KIDNEY; MALE; RATS; RATS, WISTAR; STOMACH;

RATTUS;

EID: 78649448956     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2009.08.011     Document Type: Article

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