Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
Tanaka Y., et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet 2009, 41(10):1105-1109.
Replicated association between an interleukin-28B gene variant and a sustained response to pegylated interferon and ribavirin. Gastroenterology
McCarthy JJ, et al. Replicated association between an interleukin-28B gene variant and a sustained response to pegylated interferon and ribavirin. Gastroenterology 2010;138(7):2307-14.
Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology
Rauch A, et al. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology 2010;138(4):1338-45.
IL28B polymorphism is significantly correlated with IFN anti-viral effectiveness on first day of pegylated interferon-alpha and ribavirin therapy of chronic HCV infection
Neumann A., et al. IL28B polymorphism is significantly correlated with IFN anti-viral effectiveness on first day of pegylated interferon-alpha and ribavirin therapy of chronic HCV infection. J Hepatol 2010, 52(Suppl. 1):S468.
Predictive role of IL28B C/C genotype on SVR and RVR in patients with genotype 2/3 chronic infection
Mangia A., et al. Predictive role of IL28B C/C genotype on SVR and RVR in patients with genotype 2/3 chronic infection. J Hepatol 2010, 52(Suppl. 1):S56.
A chromosome 19 SNP (rs12979860) predicts outcome (EVR/SVR) in HCV patients treated with interferon, independent of pegylation or ribavirin
Asselah T., et al. A chromosome 19 SNP (rs12979860) predicts outcome (EVR/SVR) in HCV patients treated with interferon, independent of pegylation or ribavirin. J Hepatol 2010, 52(Suppl.1):S456.
Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics
Marcello T., et al. Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics. Gastroenterology 2006, 131(6):1887-1898.
IFN stimulated geen expression in the liver is a better predictor of treatment response in chronic hepatitis C than the IL28B (IFNlambda3) genotype
Dill M.T., et al. IFN stimulated geen expression in the liver is a better predictor of treatment response in chronic hepatitis C than the IL28B (IFNlambda3) genotype. J Hepatol 2010, 52(Suppl. 1):S461.
Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology
Thompson AJ, et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology 2010;139.