Nonsense-mediated mRNA decay (NMD) blockage promotes nonsense mRNA stabilization in protein 4.1R deficient cells carrying the 4.1R Coimbra variant of hereditary elliptocytosis

Blood Cells, Molecules, and Diseases

Volumn 45, Issue 4, 2010, Pages 284-288

  Morinière, Madeleine ^a   Delhommeau, François ^b   Calender, Alain ^c   Ribeiro, Leticia ^d   Delaunay, Jean ^b   Baklouti, Faouzi ^a  

^a UNIVERSITÉ LYON 1   (France)

^b INSERM   (France)

^c EDOUARD HERRIOT HOSPITAL   (France)

^d CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

Author keywords

MRNA; Mutation; NMD; Red cell membrane disorders; Splicing

Indexed keywords

CAFFEINE; CYCLOHEXIMIDE; ERYTHROCYTE BAND 4.1 PROTEIN; ISOPROTEIN; MESSENGER RNA; REGULATOR PROTEIN; UNCLASSIFIED DRUG; UP FRAMESHIFT PROTEIN 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ERYTHROID CELL; EXON; GENE MUTATION; HEMOLYTIC ANEMIA; HEREDITARY ELLIPTOCYTOSIS; HOMOZYGOSITY; INTRON RETENTION; LYMPHOID CELL; MOUSE; MUTATION RATE; MUTATIONAL ANALYSIS; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TARGETING; RIBOSOMAL FRAMESHIFTING; RNA SPLICING; RNA STABILITY; TRANSLATION REGULATION;

EID: 78649445777     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2010.08.011     Document Type: Article

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