Centchroman mediated apoptosis involves cross-talk between extrinsic/intrinsic pathways and oxidative regulation

Life Sciences

Volumn 87, Issue 23-26, 2010, Pages 750-758

  Nigam, Manisha ^a,d   Singh, Neetu ^a   Ranjan, Vishal ^a,d   Zaidi, Deeba ^a,b   Sharma, Ramesh ^a   Nigam, Deepti ^c   Gupta, Dwijendra Kumar ^d   Sundaram, Shanthy ^c   Balapure, Anil Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b INTEGRAL UNIVERSITY   (India)

^c CSIR NATIONAL BOTANICAL RESEARCH INSTITUTE   (India)

^d UNIVERSITY OF ALLAHABAD   (India)

Author keywords

Apoptosis; Breast cancer; Centchroman; MCF 7; MDA MB 231; Tamoxifen

Indexed keywords

APOPTOSIS INDUCING FACTOR; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CATALASE; CENTCHROMAN; CYCLIN D1; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; CYCLINE; CYCLOHEXIMIDE; DACTINOMYCIN; FAS LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN P53; SUPEROXIDE DISMUTASE; TAMOXIFEN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL STRAIN MCF 7; CELL SURVIVAL; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CENTCHROMAN; CYCLOHEXIMIDE; DACTINOMYCIN; DOWN-REGULATION; ESTROGEN ANTAGONISTS; FEMALE; HUMANS; IMMUNOPRECIPITATION; OXIDATIVE STRESS; TAMOXIFEN; UP-REGULATION;

EID: 78649445742     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.10.015     Document Type: Article

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