Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients

Annals of Thoracic Surgery

Volumn 90, Issue 6, 2010, Pages 1893-1898

  Phillippi, Julie A ^a   Eskay, Michael A ^a   Kubala, Adam A ^a   Pitt, Bruce R ^a   Gleason, Thomas G ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; METALLOTHIONEIN; REACTIVE OXYGEN METABOLITE; VASCULOTROPIN;

ADULT; ANIMAL TISSUE; ARTICLE; ASCENDING AORTA; BICUSPID AORTIC VALVE; CELL VIABILITY; DISEASE PREDISPOSITION; EXTRACELLULAR MATRIX; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; THORACIC AORTA ANEURYSM; WILD TYPE;

ADULT; ANIMALS; AORTIC VALVE; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HEART VALVE DISEASES; HUMANS; MICE; MICE, INBRED C57BL; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; OXIDATIVE STRESS; PROGNOSIS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 78649433790     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2010.07.069     Document Type: Article

References (32)

1. C. Ward Clinical significance of the bicuspid aortic valve Heart 83 2000 81 85
2. T.G. Gleason Heritable disorders predisposing to aortic dissection Semin Thorac Cardiovasc Surg 17 2005 274 281
3. M.A. Coady, J.A. Rizzo, L.J. Goldstein, and J.A. Elefteriades Natural history, pathogenesis, and etiology of thoracic aortic aneurysms and dissections Cardiol Clin 17 1999 615 635 vii
4. J.A. Phillippi, E.A. Klyachko, J.P.T. Kenny, M.A. Eskay, R.C. Gorman, and T.G. Gleason Basal and oxidative stress-induced expression of metallothionein is decreased in ascending aortic aneurysms of bicuspid aortic valve patients Circulation 119 2009 2498 2506
5. C.X. Fang, T.A. Doser, X. Yang, N. Sreejayan, and J. Ren Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt Aging Cell 5 2006 177 185
6. W. Feng, Y. Wang, L. Cai, and Y.J. Kang Metallothionein rescues hypoxia-inducible factor-1 transcriptional activity in cardiomyocytes under diabetic conditions Biochem Biophys Res Commun 360 2007 286 289
7. Y. Kondo, J.M. Rusnak, D.G. Hoyt, C.E. Settineri, B.R. Pitt, and J.S. Lazo Enhanced apoptosis in metallothionein null cells Mol Pharmacol 52 1997 195 201
8. J. Ejiri, N. Inoue, and T. Tsukube Oxidative stress in the pathogenesis of thoracic aortic aneurysm: protective role of statin and angiotensin II type 1 receptor blocker Cardiovasc Res 59 2003 988 996
9. C. Fiorillo, M. Becatti, and M. Attanasio Evidence for oxidative stress in plasma of patients with Marfan syndrome Int J Cardiol 2010 May 25 Epub
10. L. Pereira, S.Y. Lee, and B. Gayraud Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1 Proc Natl Acad Sci USA 96 1999 3819 3823
11. S. Rajagopalan, X.P. Meng, S. Ramasamy, D.G. Harrison, and Z.S. Galis Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro Implications for atherosclerotic plaque stability J Clin Invest 98 1996 2572 2579
12. H.H. Yang, C. van Breemen, and A.W. Chung Vasomotor dysfunction in the thoracic aorta of Marfan syndrome is associated with accumulation of oxidative stress Vasc Pharmacol 52 2010 37 45
13. M. Penkowa, J. Carrasco, and M. Giralt Altered central nervous system cytokine-growth factor expression profiles and angiogenesis in metallothionein-I+II deficient mice J Cereb Blood Flow Metab 20 2000 1174 1189
14. R.J. Epstein VEGF signaling inhibitors: more pro-apoptotic than anti-angiogenic Cancer Metastasis Rev 26 2007 443 452
15. Y. Wu, A.T. Hooper, and Z. Zhong The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma Int J Cancer 119 2006 1519 1529 (Pubitemid 44258756)
16. Z. Yang, X. Mo, and Q. Gong Critical effect of VEGF in the process of endothelial cell apoptosis induced by high glucose Apoptosis 13 2008 1331 1343
17. V. Lesauskaite, P. Tanganelli, and C. Sassi Smooth muscle cells of the media in the dilatative pathology of ascending thoracic aorta: morphology, immunoreactivity for osteopontin, matrix metalloproteinases, and their inhibitors Hum Pathol 32 2001 1003 1011
18. H. Williams, J.L. Johnson, C.L. Jackson, S.J. White, and S.J. George MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis Cardiovasc Res 87 2010 137 146
19. R.W. Thompson, D.R. Holmes, and R.A. Mertens Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages J Clin Invest 96 1995 318 326
20. M.L. McCormick, D. Gavrila, and N.L. Weintraub Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms Arterioscler Thromb Vasc Biol 27 2007 461 469
21. K. Grote, I. Flach, and M. Luchtefeld Mechanical stretch enhances mRNA expression and proenzyme release of matrix metalloproteinase-2 (MMP-2) via NAD(P)H oxidase-derived reactive oxygen species Circ Res 92 2003 e80 e86
22. K. Hishikawa, B.S. Oemar, Z. Yang, and T.F. Luscher Pulsatile stretch stimulates superoxide production and activates nuclear factor-kappa B in human coronary smooth muscle Circ Res 81 1997 797 803
23. C.D. Klaassen, and J. Liu Metallothionein transgenic and knock-out mouse models in the study of cadmium toxicity J Toxicol Sci 23 Suppl 2 1998 97 102
24. L.L. Pearce, K. Wasserloos, C.M. St Croix, R. Gandley, E.S. Levitan, and B.R. Pitt Metallothionein, nitric oxide and zinc homeostasis in vascular endothelial cells J Nutr 130 Suppl 2000 1467 1470
25. P.J. Bernal, K. Leelavanichkul, and E. Bauer Nitric-oxide-mediated zinc release contributes to hypoxic regulation of pulmonary vascular tone Circ Res 102 2008 1575 1583
26. C. Corpechot, V. Barbu, and D. Wendum Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis Hepatology 35 2002 1010 1021
27. J. Rossert, C. Terraz, and S. Dupont Regulation of type I collagen genes expression Nephrol Dial Transplant 15 Suppl 6 2000 66 68
28. X. Wang, S.A. LeMaire, and L. Chen Increased collagen deposition and elevated expression of connective tissue growth factor in human thoracic aortic dissection Circulation 114 Suppl 2006 I200 I205
29. M.A. Whittle, P.S. Hasleton, J.C. Anderson, and A.C. Gibbs Collagen in dissecting aneurysms of the human thoracic aorta Increased collagen content and decreased collagen concentration may be predisposing factors in dissecting aneurysms Am J Cardiovasc Pathol 3 1990 311 319
30. J.A. Jones, J.A. Zavadzkas, and E.I. Chang Cellular phenotype transformation occurs during thoracic aortic aneurysm development J Thorac Cardiovasc Surg 2010 March 8 Epub
31. J.J. Maleszewski, D.V. Miller, J. Lu, H.C. Dietz, and M.K. Halushka Histopathologic findings in ascending aortas from individuals with Loeys-Dietz syndrome (LDS) Am J Surg Pathol 33 2009 194 201
32. L. de Figueiredo Borges, R.G. Jaldin, R.R. Dias, N.A. Stolf, J.B. Michel, and P.S. Gutierrez Collagen is reduced and disrupted in human aneurysms and dissections of ascending aorta Hum Pathol 39 2008 437 443