Targeted in vivo computed tomography (CT) imaging of tissue ACE using concentrated lisinopril-capped gold nanoparticle solutions

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7674, Issue , 2010, Pages

  Daniel, Marie Christine ^a   Aras, Omer ^b   Smith, Mark F ^b   Nan, Anjan ^c   Fleiter, Thorsten ^b  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^b UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

ACE inhibitors; ACE targeting; CT imaging; Gold nanoparticles; Lisinopril

Indexed keywords

ACE INHIBITORS; ACE TARGETING; CT IMAGING; GOLD NANOPARTICLES; LISINOPRIL;

CARDIOLOGY; GOLD; HYDROPHOBICITY; NANOPARTICLES; PATIENT MONITORING; PHYSIOLOGY; SENSORS;

COMPUTERIZED TOMOGRAPHY;

EID: 78649413360     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.849841     Document Type: Conference Paper

References (28)

1. Borm, P. J. A. and Mueller-Schulte, D., "Nanoparticles in medicine," Part. Toxicol., 387-411 (2007).
2. Patel, P., Acharya, M. A. and Patel, J., "Nanoparticles in cancer research: a novel drug delivery & pharmacological approach," Drug Delivery Technol., 9(48), 50-52 (2009).
3. Zhang, L., Gu, F. X., Chan, J. M., Wang, A. Z., Langer, R. S. and Farokhzad, O. C., "Nanoparticles in Medicine: Therapeutic Applications and Developments," Clin. Pharmacol. Ther., 83, 761-769 (2008).
4. Gindy, M. E. and Prud'homme, R. K., "Multifunctional nanoparticles for imaging, delivery and targeting in cancer therapy," Expert Opin. Drug Delivery, 6, 865-878 (2009).
5. Labhasetwar, V., Zborowski, M., Abramson, A. R. and Basilion, J. P., "Nanoparticles for Imaging, Diagnosis, and Therapeutics," Mol. Pharmaceutics, 6, 1261-1262 (2009).
6. Liong, M., Angelos, S., Choi, E., Patel, K., Stoddart, J. F. and Zink, J. I., "Mesostructured multifunctional nanoparticles for imaging and drug delivery," J. Mater. Chem., 19, 6251-6257 (2009).
7. Prasad, P. N., "Multifunctional Nanoparticles with Imaging and Therapeutics Functions for Nanomedicine," Mater. Res. Soc. Symp. Proc., 1019E, Paper #: 1019-FF03-01 (2007).
8. Rusinek, H., Naidich, D. P., McGuinness, G., Leitman, B. S., McCauley, D. I., Krinsky, G. A., Clayton, K. and Cohen, H., "Pulmonary nodule detection: low-dose versus conventional CT," Radiology, 209, 243-9 (1998).
9. Fu, Y. Nitecki, D. E., Maltby, D., Simon, G. H., Berejnoi, K., Raatschen, H.-J., Yeh, B. M., Shames, D. M. and Brasch, R. C., "Dendritic Iodinated Contrast Agents with PEG-Cores for CT Imaging: Synthesis and Preliminary Characterization," Bioconjugate Chem., 17, 1043-1056 (2006).
10. deKrafft, K. E., Xie, Z., Cao, G., Tran, S., Ma, L., Zhou, O. Z. and Lin, W., "Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography," Angew. Chem. Int. Ed., 48, 9901-9904 (2009).
11. Hasebroock, K. M. and Serkova, N. J., "Toxicity of MRI and CT contrast agents," Expert Opin. Drug Metab. Toxicol., 5, 403-416 (2009).
12. Roentgen, W., "Diagnostic imaging 100 years ago," Servir, 44, 207-10 (1996).
13. Cai, Q.-Y., Kim, S. H., Choi, K. S., Kim, S. Y., Byun, S. J., Kim, K. W., Park, S. H., Juhng, S. K. and Yoon, K.-H., "Colloidal Gold Nanoparticles as a Blood-Pool Contrast Agent for X-ray Computed Tomography in Mice," Invest. Radiol., 42, 797-806 (2007).
14. Kim, D., Park, S., Lee, J. H., Jeong, Y. Y. and Jon, S., "Antibiofouling Polymer-Coated Gold Nanoparticles as a Contrast Agent for in Vivo X-ray Computed Tomography Imaging," J. Am. Chem. Soc., 129, 7661-7665 (2007).
15. Popovtzer, R., Agrawal, A., Kotov, N. A., Popovtzer, A., Balter, J., Carey, T. E. and Kopelman, R., "Targeted Gold Nanoparticles Enable Molecular CT Imaging of Cancer," Nano Lett., 8, 4593-4596 (2008).
16. Hainfeld, J. F., Slatkin, D. N., Focella, T. M. and Smilowitz, H. M., "Gold nanoparticles: a new X-ray contrast agent," Br. J. Radiol., 79, 248-253 (2006).
17. Daniel, M.-C. and Astruc, D., "Gold Nanoparticles: Assembly, Supramolecular Chemistry, Quantum-Size-Related Properties, and Applications toward Biology, Catalysis, and Nanotechnology," Chem. Rev., 104, 293-346 (2004).
18. Murphy, C. J., Gole, A. M., Stone, J. W., Sisco, P. N., Alkilany, A. M., Goldsmith, E. C. and Baxter, S. C., "Gold Nanoparticles in Biology: Beyond Toxicity to Cellular Imaging," Acc. Chem. Res., 41, 1721-1730 (2008).
19. Shukla, R., Bansal, V., Chaudhary, M., Basu, A., Bhonde, R. R. and Sastry, M., "Biocompatibility of Gold Nanoparticles and Their Endocytotic Fate Inside the Cellular Compartment: A Microscopic Overview," Langmuir, 21, 10644-10654 (2005).
20. Aras, O., Messina Steven, A., Shirani, J., Eckelman William, C. and Dilsizian, V., "The role and regulation of cardiac angiotensin-converting enzyme for noninvasive molecular imaging in heart failure," Curr Cardiol Rep, 9, 150-8 (2007).
21. Aras, O. and Dilsizian, V., "Targeting tissue angiotensin-converting enzyme for imaging cardiopulmonary fibrosis," Curr Cardiol Rep, 10, 128-34 (2008).
22. Li, Y., Baeta, C., Aras, O. and Daniel, M.-C., "Preparation of lisinopril-capped gold nanoparticles for molecular imaging of angiotensin-converting enzyme," Proc. SPIE, 7313, 731304/1-731304/8 (2009).
23. Ji, X., Song, X., Li, J., Bai, Y., Yang, W. and Peng, X., "Size Control of Gold Nanocrystals in Citrate Reduction: The Third Role of Citrate," J. Am. Chem. Soc., 129, 13939-13948 (2007).
24. Lin, S.-Y., Tsai, Y.-T., Chen, C.-C., Lin, C.-M. and Chen, C.-h., "Two-Step Functionalization of Neutral and Positively Charged Thiols onto Citrate-Stabilized Au Nanoparticles," J. Phys. Chem. B, 108, 2134-2139 (2004).
25. Wang, S.-L., Chuang, C.-H. and Lin, S.-Y., "pH-dependent coordination of metal-lisinopril complex investigated by attenuated total reflection/Fourier transform infrared spectroscopy," Chem. Pharm. Bull., 50, 78-82 (2002).
26. Haiss, W., Thanh, N. T. K., Aveyard, J. and Fernig, D. G., "Determination of Size and Concentration of Gold Nanoparticles from UV-Vis Spectra," Anal. Chem., 79, 4215-4221 (2007).
27. Leff, D. V., Brandt, L. and Heath, J. R., "Synthesis and Characterization of Hydrophobic, Organically Soluble Gold Nanocrystals Functionalized with Primary Amines," Langmuir, 12, 4723-4730 (1996).
28. Aslan, K. and Perez-Luna, V. H., "Surface Modification of Colloidal Gold by Chemisorption of Alkanethiols in the Presence of a Nonionic Surfactant," Langmuir, 18, 6059-6065 (2002).