-
1
-
-
34047276812
-
Autosomal dominant polycystic kidney disease
-
V.E. Torres, P.C. Harris, and Y. Pirson Autosomal dominant polycystic kidney disease Lancet 369 2007 1287
-
(2007)
Lancet
, vol.369
, pp. 1287
-
-
Torres, V.E.1
Harris, P.C.2
Pirson, Y.3
-
2
-
-
67649841563
-
Autosomal dominant polycystic kidney disease: The last 3 years
-
V.E. Torres, and P.C. Harris Autosomal dominant polycystic kidney disease: the last 3 years Kidney Int 76 2009 149
-
(2009)
Kidney Int
, vol.76
, pp. 149
-
-
Torres, V.E.1
Harris, P.C.2
-
3
-
-
33645769011
-
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease
-
J.M. Shillingford, N.S. Murcia, and C.H. Larson The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease Proc Natl Acad Sci USA 103 2006 5466
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5466
-
-
Shillingford, J.M.1
Murcia, N.S.2
Larson, C.H.3
-
4
-
-
77949528561
-
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
-
R. Dere, P.D. Wilson, and R.N. Sandford Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR PLoS One 5 2010 e9239
-
(2010)
PLoS One
, vol.5
, pp. 9239
-
-
Dere, R.1
Wilson, P.D.2
Sandford, R.N.3
-
5
-
-
18744380752
-
Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease
-
Y. Tao, J. Kim, and R.W. Schrier Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease J Am Soc Nephrol 16 2005 46
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 46
-
-
Tao, Y.1
Kim, J.2
Schrier, R.W.3
-
6
-
-
33644859253
-
Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD)
-
P.R. Wahl, A.L. Serra, and M. Le Hir Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD) Nephrol Dial Transplant 21 2006 598
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 598
-
-
Wahl, P.R.1
Serra, A.L.2
Le Hir, M.3
-
7
-
-
34447514158
-
Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease
-
M. Wu, P.R. Wahl, and M. Le Hir Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease Kidney Blood Press Res 30 2007 253
-
(2007)
Kidney Blood Press Res
, vol.30
, pp. 253
-
-
Wu, M.1
Wahl, P.R.2
Le Hir, M.3
-
8
-
-
71449093471
-
Pulse mTOR inhibitor treatment effectively controls cyst growth but leads to severe parenchymal and glomerular hypertrophy in rat polycystic kidney disease
-
M. Wu, A. Arcaro, and Z. Varga Pulse mTOR inhibitor treatment effectively controls cyst growth but leads to severe parenchymal and glomerular hypertrophy in rat polycystic kidney disease Am J Physiol Renal Physiol 297 2009 F1597
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. 1597
-
-
Wu, M.1
Arcaro, A.2
Varga, Z.3
-
9
-
-
67651087241
-
Long-term rapamycin therapy in the Han:SPRD rat model of polycystic kidney disease (PKD)
-
I. Zafar, F.A. Belibi, and Z. He Long-term rapamycin therapy in the Han:SPRD rat model of polycystic kidney disease (PKD) Nephrol Dial Transplant 24 2009 2349
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 2349
-
-
Zafar, I.1
Belibi, F.A.2
He, Z.3
-
10
-
-
67649872366
-
Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis
-
V.H. Gattone 2nd, R.M. Sinders, and T.A. Hornberger Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis Kidney Int 76 2009 178
-
(2009)
Kidney Int
, vol.76
, pp. 178
-
-
Sinders, R.M.1
Hornberger, T.A.2
-
11
-
-
77949887674
-
Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1
-
J.M. Shillingford, K.B. Piontek, and G.G. Germino Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1 J Am Soc Nephrol 21 2010 489
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 489
-
-
Shillingford, J.M.1
Piontek, K.B.2
Germino, G.G.3
-
12
-
-
40449138290
-
Sirolimus reduces polycystic liver volume in ADPKD patients
-
Q. Qian, H. Du, and B.F. King Sirolimus reduces polycystic liver volume in ADPKD patients J Am Soc Nephrol 19 2008 631
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 631
-
-
Qian, Q.1
Du, H.2
King, B.F.3
-
13
-
-
77950603185
-
Rapamycin reduces kidney volume and delays the loss of renal function in a patient with autosomal-dominant polycystic kidney disease
-
R. Peces, C. Peces, and V. Prez-Dueas Rapamycin reduces kidney volume and delays the loss of renal function in a patient with autosomal-dominant polycystic kidney disease NDT Plus 2 2009 133
-
(2009)
NDT Plus
, vol.2
, pp. 133
-
-
Peces, R.1
Peces, C.2
Prez-Dueas, V.3
-
14
-
-
71749087934
-
Sirolimus therapy for patients with adult polycystic kidney disease: A pilot study
-
A.R. Soliman, E. Ismail, and S. Zamil Sirolimus therapy for patients with adult polycystic kidney disease: a pilot study Transplant Proc 41 2009 3639
-
(2009)
Transplant Proc
, vol.41
, pp. 3639
-
-
Soliman, A.R.1
Ismail, E.2
Zamil, S.3
-
15
-
-
33646678189
-
CRISP Investigators: Volume progression in polycystic kidney disease
-
J.J. Grantham, V.E. Torres, and A.B. Chapman CRISP Investigators: Volume progression in polycystic kidney disease N Engl J Med 354 2006 2122
-
(2006)
N Engl J Med
, vol.354
, pp. 2122
-
-
Grantham, J.J.1
Torres, V.E.2
Chapman, A.B.3
-
16
-
-
58149171924
-
Increases in kidney volume in autosomal dominant polycystic kidney disease can be detected within 6 months
-
A.D. Kistler, D. Poster, and F. Krauer Increases in kidney volume in autosomal dominant polycystic kidney disease can be detected within 6 months Kidney Int 75 2009 235
-
(2009)
Kidney Int
, vol.75
, pp. 235
-
-
Kistler, A.D.1
Poster, D.2
Krauer, F.3
-
17
-
-
35748948350
-
Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study
-
A.L. Serra, A.D. Kistler, and D. Poster Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study BMC Nephrol 8 2007 13
-
(2007)
BMC Nephrol
, vol.8
, pp. 13
-
-
Serra, A.L.1
Kistler, A.D.2
Poster, D.3
|