HLA Class I molecules partner with integrin β4 to stimulate endothelial cell proliferation and migration

Science Signaling

Volumn 3, Issue 149, 2010, Pages

  Zhang, Xiaohai ^a   Rozengurt, Enrique ^a   Reed, Elaine F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA4 INTEGRIN; HLA ANTIGEN CLASS 1; KALININ; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN SUBUNIT; STEROID RECEPTOR COACTIVATOR 1; CELL ADHESION MOLECULE; ONCOPROTEIN; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GRAFT REJECTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSPLANT VASCULOPATHY; VASCULAR DISEASE; ANALYSIS OF VARIANCE; ANIMAL; CELL LINE; CELL MOTION; CONFOCAL MICROSCOPY; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; IMMUNOPRECIPITATION; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; WESTERN BLOTTING; WOUND HEALING;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL ADHESION MOLECULES; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE KNOCKDOWN TECHNIQUES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOPRECIPITATION; INTEGRIN BETA4; MICE; MICROSCOPY, CONFOCAL; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TRANSFECTION; WOUND HEALING;

EID: 78649404738     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2001158     Document Type: Article

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57. Acknowledgments: We thank M. Edidin for his valuable comments. Funding: This work was supported by the National Institute of Allergy and Infectious Diseases grant RO1 AI 042819 (E.F.R.); NIH grant U01AI077821 (E.F.R.); the National Heart, Lung and Blood Institute grant RO1 HL 090995 (E.F.R.); and NIH grants R0-1 DK 55003 (E.R.), R0-1 DK56930 (E.R.), R21CA137292 (E.R.), and P30 DK41301 (E.R.). Author contributions: X.Z. and E.F.R. carried out project planning, experimental design, experimental work, data analysis, and manuscript preparation; E.R. carried out experimental design, data analysis, and manuscript preparation; and E.F.R. supervised the project. Competing interests: The authors declare that they have no competing interests.