Biological activity of sea anemone proteins: II. Cytolysis and cell line toxicity

Indian Journal of Experimental Biology

Volumn 48, Issue 12, 2010, Pages 1233-1236

  Ravindran, Vinoth S ^a,c   Kannan, L ^a   Venkateshvaran, K ^b  

^a ANNAMALAI UNIVERSITY   (India)

^b CENTRAL INSTITUTE OF FISHERIES EDUCATION   (India)

^c Suganthi Devadason Marine Research Institute   (India)

Author keywords

Anti cancer; Cytolytic; Erythrocytes; L929; P388; Sea anemone protein

Indexed keywords

MARINE TOXIN; PROTEIN;

ANIMAL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CHICKEN; DRUG EFFECT; ERYTHROCYTE; FIBROBLAST; GOAT; HEMOLYSIS; HUMAN; LEUKEMIA; METABOLISM; MOUSE; PATHOLOGY; SEA ANEMONE;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CHICKENS; ERYTHROCYTES; FIBROBLASTS; GOATS; HEMOLYSIS; HUMANS; LEUKEMIA; MARINE TOXINS; MICE; PROTEINS; SEA ANEMONES;

ACTINIARIA; ANEMONE; CAPRA HIRCUS; HETERACTIS MAGNIFICA; STICHODACTYLA HADDONI;

EID: 78649401792     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Anderluh G, Serra M D, Viero G, Guella G, Macek P & Menestrina G, Pore formation by equinatoxin II, a eukaryotic protein toxin, occurs by induction of nonlamellar lipid structures, J Biol Chem, 278 (2003) 45216.
2. Anderluh G, & Macek P, Cytolytic peptide and protein toxins from sea anemones, Toxicon, 40 (2002) 111.
3. Auguoto B, Koldo M, Ariana B, Gutierrez A, Ana R V, Juan M & Gonzalez M. Purification, cloning and characterization of fragaceotoxin C, a novel actinoporin from the sea anemone Actina fragacea, Toxicon, 54 (2009) 869.
4. Soletti R C, De-Faria, Gieselle P, Vernal J, Terenzi H, Anduluh G, Borges H L, Moura N, Vivaldo G & Nelson H, Potentiation of anti cancer drug cytotoxicity by sea anemone pone forming proteins in human glioblastoma cells, Anti Cancer Drugs, 19 (2008) 517.
5. Avila A D, de Acosta M C & Lage A, A new immunotoxin built by linking a hemolytic toxin to a monoclonal antibody specific for immature T lymphocytes, Int J Cancer, 42 (1988) 568.
6. Pederzolli C, Belmonte G, Dalla Serra M, Macek P & Menestrina G, Biochemical and cytotoxic properties of conjugates of transferrin with Equinatoxin II, a cytolysin from sea anemone, Bioconj Chem, 6 (1995) 166.
7. Jiang X, Chen H, Yang W, Liu W, Wei J, Tu H, Xie X, Wang L & Xu A, Functional expression and characterization of an acidic actinoporin from sea anemone Sagartia rosea, Biochem Biophys Res Comm, 312 (2003) 562.
8. Ravindram Vinod S, Kannan L & Venkateshvaran K, Biological activity of sea anemone proteins: I. Toxicity and histopathology, Indian J Exp Biol, 48 (2010) 1225.
9. Sunahara S, Muramoto K, Tenma K & Kamiya H, Amino acid sequence of two sea anemone toxins from Anthopleura fuscoviridis, Toxicon, 25 (1987) 211.
10. Shiomi K, Takamiya M, Yamanaka H & Kikuchi T, Purification of a lethal factor in the skin secretion from the oriental catfish Plotosus lineatus, Nippon suisan Gakkaishi, 53 (1987) 1275.
11. Lowry O H, Rosebrough N J, Fearr A L & Randall R J, Protein measurement with folin phenol reagent, J Biol Chem, 193 (1951) 265.
12. Paniparasad K & Venkateshvaran K, Microhemolytic assay in Training manual on advanced techniques in marine biotoxinology, edited by Venkateshvaran K & Paniprasad K (CAS in Fishery Science, Central Institute of Fisheries Education, Mumbai, India) 1997, 41.
13. Macek P & Lebez D, Isolation and characterization of three lethal and hemolytic toxins from the sea anemone Actinia equina L, Toxicon, 26 (1988) 441.
14. Monastyrnaya M M, Zykova T A, Apalikova O V, Shwets T V & Kozloskaya E P, Biologically active polypeptides from the tropical sea anemone Radianthus macrodactylus, Toxicon, 40 (2002) 1197.
15. Avila A D, de Acosta M C & Lage A, A carcinoembryonic antigen-directed immunotoxin built by linking a monoclonal antibody to a hemolytic toxin, Int J Cancer, 43 (1989) 926.
16. Giraldi T, Ferlan I & Romeo D, Antitumor activity of equinatoxin, Chem Biol Interact, 13 (1976) 199.
17. Zorec R, Tester M, Macek P & Mason W T, Cytotoxicity of equinatoxin II from the sea anemone Actinia equina involves ion channel formation and an increase in intracellular calcium activity, J Membr Biol, 118 (1990) 243.
18. Batista U, Macek P & Sedmak B, The cytotoxic and cytolytic activity of equinatoxin II from the sea anemone Actinia equina, Cell Biol Int Rep, 14 (1990) 1013.