Design of optimal sampling times for pharmacokinetic trials via spline approximation

Turkish Journal of Electrical Engineering and Computer Sciences

Volumn 18, Issue 6, 2010, Pages 1019-1030

  Asyali, Musa Hakan ^a  

^a ZIRVE UNIVERSITY   (Turkey)

Author keywords

Optimal sampling time design; Pharmacokinetic parameters; Sequential quadratic programming; Spline approximation

Indexed keywords

ACCURATE ESTIMATION; CRITERION FUNCTIONS; CUBIC SPLINE; DRUG ABSORPTION; DRUG DELIVERY FORMULATIONS; GLOBAL OPTIMALITY; NUMBER OF SAMPLES; OPTIMAL SAMPLING; OVER SAMPLING; PHARMACOKINETIC PARAMETERS; PHARMACOKINETIC STUDIES; PIECEWISE LINEAR APPROXIMATIONS; SAMPLE COLLECTION; SEQUENTIAL QUADRATIC PROGRAMMING; SPLINE APPROXIMATION; SPLINE APPROXIMATIONS;

DESIGN; DRUG DELIVERY; ESTIMATION; PHARMACOKINETICS; QUADRATIC PROGRAMMING; SPLINES;

OPTIMIZATION;

EID: 78649384190     PISSN: 13000632     EISSN: 13036203     Source Type: Journal    
DOI: 10.3906/elk-0911-308     Document Type: Article

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