-
1
-
-
39149145482
-
Prevalence, treatment, and control of diagnosed diabetes in the U.S. national health and nutrition examination survey 1999-2004
-
Ong KL, Cheung BMY, Wong LYF et al. Prevalence, treatment, and control of diagnosed diabetes in the U.S. national health and nutrition examination survey 1999-2004. Ann. Epidemiol. 18(3), 222-229 (2008).
-
(2008)
Ann. Epidemiol.
, vol.18
, Issue.3
, pp. 222-229
-
-
Ong, K.L.1
Bmy, C.2
Lyf, W.3
-
2
-
-
67649227935
-
The current unmet need in Type 2 diabetes mellitus: Addressing glycemia and cardiovascular disease
-
Levy P. The current unmet need in Type 2 diabetes mellitus: addressing glycemia and cardiovascular disease. Postgrad. Med. 121(3 Suppl. 1), 7-12 (2009).
-
(2009)
Postgrad. Med.
, vol.121
, Issue.3 SUPPL. 1
, pp. 7-12
-
-
Levy, P.1
-
3
-
-
64749100501
-
Medical management of hyperglycemia in Type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
®, package insert. Amylin Pharmaceuticals, Inc., San Diego, CA, USA
-
®, package insert. Amylin Pharmaceuticals, Inc., San Diego, CA, USA.
-
(2009)
Diabetes Care
, vol.32
, Issue.1
, pp. 193-203
-
-
Nathan, D.M.1
Buse, J.B.2
Davidson, M.B.3
-
4
-
-
33744968835
-
Achievement of American Diabetes Association clinical practice recommendations among U.S. adults with diabetes 1999-2002: The national health and nutrition examination survey
-
Resnick HE, Foster GL, Bardsley J, Ratner RE. Achievement of American Diabetes Association clinical practice recommendations among U.S. adults with diabetes, 1999-2002: the national health and nutrition examination survey. Diabetes Care 29(3), 531-537 (2006).
-
(2006)
Diabetes Care
, vol.29
, Issue.3
, pp. 531-537
-
-
Resnick, H.E.1
Foster, G.L.2
Bardsley, J.3
Ratner, R.E.4
-
6
-
-
54349117353
-
Canadian Diabetes Association 2008 clinical practice guidelines for the prevention and management of diabetes in Canada
-
Canadian Diabetes Association Clinical Practice Guidelines Expert Committee
-
Canadian Diabetes Association Clinical Practice Guidelines Expert Committee. Canadian Diabetes Association 2008 clinical practice guidelines for the prevention and management of diabetes in Canada. Can. J. Diabetes. 32(Suppl. 1), S1-S201 (2008).
-
(2008)
Can. J. Diabetes.
, vol.32
, Issue.SUPPL. 1
-
-
-
7
-
-
75549091263
-
Statement by an American Association of Clinical Endocrinologists/ American College of Endocrinology consensus panel on Type 2 diabetes mellitus: An algorithm for glycemic control
-
Statement by an American Association of Clinical Endocrinologists Endocr. Pract.
-
Rodbard H W, Jellinger PS, Davidson JA et al. Statement by an American Association of Clinical Endocrinologists/American College of Endocrinology consensus panel on Type 2 diabetes mellitus: an algorithm for glycemic control. Endocr. Pract. 15(6), 541-559 (2009).
-
(2009)
Endocr. Pract.
, vol.15
, Issue.6
, pp. 541-559
-
-
Rodbard, H.W.1
Jellinger, P.S.2
Davidson, J.A.3
-
8
-
-
78649336705
-
Impact of treatment complexity on adherence and glycemic control: An analysis of oral anti-diabetic agents
-
Orlando, FL, USA 16-20 May
-
Pollack M, Chastek B, Williams SA. Impact of treatment complexity on adherence and glycemic control: an analysis of oral anti-diabetic agents. Presented at: International Society for Pharmacoeconomics and Outcomes Research 14th Annual International Meeting. Orlando, FL, USA, 16-20 May 2009.
-
(2009)
Presented At: International Society for Pharmacoeconomics and Outcomes Research 14th Annual International Meeting
-
-
Pollack, M.1
Chastek, B.2
Williams, S.A.3
-
9
-
-
41149118550
-
(R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl- quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action compared with other dipeptidyl peptidase-4 inhibitors
-
Thomas L, Eckhardt M, Langkopf E et al. (R)-8-(3-amino-piperidin-1-yl)-7- but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2, 6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action compared with other dipeptidyl peptidase-4 inhibitors. J. Pharmacol. Exp. Ther. 325(1), 175-182 (2008).
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.325
, Issue.1
, pp. 175-182
-
-
Thomas, L.1
Eckhardt, M.2
Langkopf, E.3
-
10
-
-
77951733112
-
P-cell stimulation by saxagliptin in patients with Type 2 diabetes
-
Henry R, Smith S, Schwartz S et al. p-cell stimulation by saxagliptin in patients with Type 2 diabetes. Diabetes 58(Suppl. 1), 447-P (2009).
-
(2009)
Diabetes
, vol.58
, Issue.SUPPL. 1
-
-
Henry, R.1
Smith, S.2
Schwartz, S.3
-
11
-
-
38149096290
-
Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance
-
Rosenstock J, Foley JE, Rendell M et al. Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance. Diabetes Care 31(1), 30-35 (2008).
-
(2008)
Diabetes Care
, vol.31
, Issue.1
, pp. 30-35
-
-
Rosenstock, J.1
Foley, J.E.2
Rendell, M.3
-
12
-
-
33847685714
-
Dipeptidyl peptidase-4 inhibitors and the management of Type 2 diabetes mellitus
-
Rosenstock J, Zinman B. Dipeptidyl peptidase-4 inhibitors and the management of Type 2 diabetes mellitus. Curr. Opin. Endocrinol. Diabetes Obes. 14(2), 98-107 (2007).
-
(2007)
Curr. Opin. Endocrinol. Diabetes Obes.
, vol.14
, Issue.2
, pp. 98-107
-
-
Rosenstock, J.1
Zinman, B.2
-
13
-
-
34548809173
-
Refecting on Type 2 diabetes prevention: More questions than answers!
-
Rosenstock J. Refecting on Type 2 diabetes prevention: more questions than answers! Diabetes Obes. Metab. 9(Suppl. 1), 3-11 (2007).
-
(2007)
Diabetes Obes Metab.
, vol.9
, Issue.SUPPL. 1
, pp. 3-11
-
-
Rosenstock, J.1
-
14
-
-
77953108350
-
A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for Type 2 diabetes
-
Frederich R, Alexander JH, Fiedorek FT et al. A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for Type 2 diabetes. Postgrad. Med. 122(3), 16-27 (2010).
-
(2010)
Postgrad. Med.
, vol.122
, Issue.3
, pp. 16-27
-
-
Frederich, R.1
Alexander, J.H.2
Fiedorek, F.T.3
-
15
-
-
78649346112
-
-
TM, package insert. Bristol-Myers Squibb, Princeton, NJ, USA &AstraZeneca, Wilmington, DE, USA
-
TM, package insert. Bristol-Myers Squibb, Princeton, NJ, USA &AstraZeneca, Wilmington, DE, USA.
-
-
-
-
16
-
-
70349333861
-
Effect of saxagliptin monotherapy in treatment-naive patients with Type 2 diabetes
-
Rosenstock J, Aguilar-Salinas C, Klein E et al. Effect of saxagliptin monotherapy in treatment-naive patients with Type 2 diabetes. Curr. Med. Res. Opin. 25(10), 2401-2411 (2009).
-
(2009)
Curr. Med. Res. Opin.
, vol.25
, Issue.10
, pp. 2401-2411
-
-
Rosenstock, J.1
Aguilar-Salinas, C.2
Klein, E.3
-
17
-
-
65549123794
-
Saxagliptin given in combination with metformin as initial therapy improves glycemic control in patients with Type 2 diabetes compared with either monotherapy: A randomized controlled trial
-
Jadzinsky M, Pfützner A, Paz-Pacheco E et al. Saxagliptin given in combination with metformin as initial therapy improves glycemic control in patients with Type 2 diabetes compared with either monotherapy: a randomized controlled trial. Diabetes Obes. Metab. 11(6), 611-622 (2009).
-
(2009)
Diabetes Obes. Metab.
, vol.11
, Issue.6
, pp. 611-622
-
-
Jadzinsky, M.1
Pfützner, A.2
Paz-Pacheco, E.3
-
18
-
-
68949212458
-
Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with Type 2 diabetes: A randomised controlled trial
-
Chacra AR, Tan GH, Apanovitch A et al. Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with Type 2 diabetes: a randomised controlled trial. Int. J. Clin. Pract. 63(9), 1395-1406 (2009).
-
(2009)
Int. J. Clin. Pract.
, vol.63
, Issue.9
, pp. 1395-1406
-
-
Chacra, A.R.1
Tan, G.H.2
Apanovitch, A.3
-
19
-
-
73149084956
-
CV181-013 investigators. Saxagliptin added to a thiazolidinedione improves glycemic control in patients with Type 2 diabetes and inadequate control on thiazolidinedione alone
-
Hollander P, Li J, Allen E, Chen R; for the CV181-013 investigators. Saxagliptin added to a thiazolidinedione improves glycemic control in patients with Type 2 diabetes and inadequate control on thiazolidinedione alone. J. Clin. Endocrinol. Metab. 94(12), 4810-4819 (2009).
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, Issue.12
, pp. 4810-4819
-
-
Hollander, P.1
Li, J.2
Allen, E.3
Chen, R.4
-
20
-
-
69549135336
-
The effcacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled Type 2 diabetes on metformin alone
-
DeFronzo RA, Hissa M, Garber AJ et al. The effcacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled Type 2 diabetes on metformin alone. Diabetes Care 32(9), 1649-1655 (2009).
-
(2009)
Diabetes Care
, vol.32
, Issue.9
, pp. 1649-1655
-
-
Defronzo, R.A.1
Hissa, M.2
Garber, A.J.3
-
21
-
-
22744449063
-
Discovery and preclinical profle of Saxagliptin (BMS-477118): A highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of Type 2 diabetes
-
Augeri DJ, Robl JA, Betebenner DA et al Discovery and preclinical profle of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of Type 2 diabetes. J. Med. Chem. 48(15), 5025-5037 (2005).
-
(2005)
J. Med. Chem.
, vol.48
, Issue.15
, pp. 5025-5037
-
-
Augeri, D.J.1
Robl, J.A.2
Betebenner, D.A.3
-
22
-
-
38649109776
-
Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation
-
Metzler WJ, Yanchunas J, Weigelt C et al. Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation. Protein Sci. 17(2), 240-250 (2008).
-
(2008)
Protein Sci.
, vol.17
, Issue.2
, pp. 240-250
-
-
Metzler, W.J.1
Yanchunas, J.2
Weigelt, C.3
-
23
-
-
70549096922
-
Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition
-
Kirby M, Yu DM, O'Connor SP, Gorrell MD. Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition. Clin. Sci. 118(1), 31-41 (2010).
-
(2010)
Clin. Sci.
, vol.118
, Issue.1
, pp. 31-41
-
-
Kirby, M.1
Yu, D.M.2
O'Connor, S.P.3
Gorrell, M.D.4
-
24
-
-
33845998516
-
The role of gut hormones in glucose homeostasis
-
Drucker DJ. The role of gut hormones in glucose homeostasis. J. Clin. Invest. 117(1), 24-32 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, Issue.1
, pp. 24-32
-
-
Drucker, D.J.1
-
25
-
-
66649134595
-
In vitro enzymologic characteristics of saxagliptin, a highly potent and selective DPP4 inhibitor with 'slow binding' characteristics
-
Abstract A29
-
Kirby MS, Dorso C, Wang A et al. In vitro enzymologic characteristics of saxagliptin, a highly potent and selective DPP4 inhibitor with 'slow binding' characteristics. Clin. Chem. Lab. Med. 46, (2008) (Abstract A29).
-
(2008)
Clin. Chem. Lab. Med.
, vol.46
-
-
Kirby, M.S.1
Dorso, C.2
Wang, A.3
-
26
-
-
77950126863
-
Dutogliptin, a dipeptidyl peptidase inhibitor for the treatment of Type 2 diabetes mellitus
-
Johnson KM. Dutogliptin, a dipeptidyl peptidase inhibitor for the treatment of Type 2 diabetes mellitus. Curr. Opin. Investig. Drugs 11(4), 55-463 (2010).
-
(2010)
Curr. Opin. Investig. Drugs
, vol.11
, Issue.4
, pp. 55-463
-
-
Johnson, K.M.1
-
27
-
-
77951702763
-
Safety tolerability pharmacokinetics and pharmacodynamics of once-daily oral doses of saxagliptin for 2 weeks in Type 2 diabetic and healthy subjects
-
Abstract 606P
-
Boulton D, Geraldes M. Safety, tolerability, pharmacokinetics and pharmacodynamics of once-daily oral doses of saxagliptin for 2 weeks in Type 2 diabetic and healthy subjects. Diabetes 56(Suppl. 1), (2007) (Abstract 606P).
-
(2007)
Diabetes
, vol.56
, Issue.SUPPL. 1
-
-
Boulton, D.1
Geraldes, M.2
-
28
-
-
43249089631
-
Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and-independent pathways
-
Ban K, Noyan-Ashraf MH, Hoefer J et al. Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and-independent pathways. Circulation 117(18), 2340-2350 (2008).
-
(2008)
Circulation
, vol.117
, Issue.18
, pp. 2340-2350
-
-
Ban, K.1
Noyan-Ashraf, M.H.2
Hoefer, J.3
-
29
-
-
77954072107
-
Effect of a high-fat meal on the pharmacokinetics of saxagliptin in healthy subjects
-
Patel CG, Zhang J, Li L et al. Effect of a high-fat meal on the pharmacokinetics of saxagliptin in healthy subjects. J. Clin. Pharmacol. 50(10), 1211-1216. (2010).
-
(2010)
J. Clin. Pharmacol.
, vol.50
, Issue.10
, pp. 1211-1216
-
-
Patel, C.G.1
Zhang, J.2
Li, L.3
-
30
-
-
79952088990
-
Infuence of renal or hepatic impairment on the pharmacokinetics of saxagliptin
-
In press
-
Boulton DW, Li L, Frevert EU et al. Infuence of renal or hepatic impairment on the pharmacokinetics of saxagliptin. Clin. Pharmacokinet. (In press).
-
Clin. Pharmacokinet
-
-
Boulton, D.W.1
Li, L.2
Frevert, E.U.3
-
31
-
-
78649347866
-
No meaningful pharmacokinetic drug-drug interactions between saxagliptin and metformin in healthy subjects
-
Denver, CO, USA 14-17 October
-
Patel C, Komoroski B, Brenner E, Li L, Boulton D. No meaningful pharmacokinetic drug-drug interactions between saxagliptin and metformin in healthy subjects. Presented at: American College of Clinical Pharmacy. Denver, CO, USA, 14-17 October 2007.
-
(2007)
Presented At: American College of Clinical Pharmacy
-
-
Patel, C.1
Komoroski, B.2
Brenner, E.3
Li, L.4
Boulton, D.5
-
32
-
-
78649347866
-
No meaningful pharmacokinetic drug-drug interaction between saxagliptin and glyburide in healthy subjects
-
Denver, CO, USA 14-17 October
-
Patel C, Komoroski B, Li L, Boulton D. No meaningful pharmacokinetic drug-drug interaction between saxagliptin and glyburide in healthy subjects. Presented at: American College of Clinical Pharmacy. Denver, CO, USA, 14-17 October 2007.
-
(2007)
Presented At: American College of Clinical Pharmacy
-
-
Patel, C.1
Komoroski, B.2
Li, L.3
Boulton, D.4
-
33
-
-
78649347866
-
No meaningful pharmacokinetic drug-drug interaction between saxagliptin and pioglitazone in healthy subjects
-
Denver, CO, USA 14-17 October
-
Patel CG, Wolf RA, Komoroski B, Li L, Boulton AJ. No meaningful pharmacokinetic drug-drug interaction between saxagliptin and pioglitazone in healthy subjects. Presented at: American College of Clinical Pharmacy. Denver, CO, USA, 14-17 October 2007.
-
(2007)
Presented At: American College of Clinical Pharmacy
-
-
Patel, C.G.1
Wolf, R.A.2
Komoroski, B.3
Li, L.4
Boulton, A.J.5
-
34
-
-
56749105553
-
No pharmacokinetic interaction between saxagliptin and digoxin in healthy subjects
-
Abstract PIII-69
-
Boulton DW, Li L, Patel CG. No pharmacokinetic interaction between saxagliptin and digoxin in healthy subjects. Clin. Pharmacol. Ther. 83(Suppl. 1), S93 (2008) (Abstract PIII-69).
-
(2008)
Clin. Pharmacol. Ther.
, vol.83
, Issue.SUPPL. 1
-
-
Boulton, D.W.1
Li, L.2
Patel, C.G.3
-
35
-
-
77952913997
-
Maalox max, famotidine or omeprazole do not meaningfully affect the pharmacokinetics of saxagliptin in healthy subjects
-
Boulton DW, Adams D, Li L et al. Maalox max, famotidine or omeprazole do not meaningfully affect the pharmacokinetics of saxagliptin in healthy subjects. Clin. Pharmacol. Ther. 83(Suppl. 1), S92 (2008).
-
(2008)
Clin. Pharmacol. Ther.
, vol.83
, Issue.SUPPL. 1
-
-
Boulton, D.W.1
Adams, D.2
Li, L.3
-
36
-
-
77951741090
-
Effect of ketoconazole on the pharmacokinetics of saxagliptin in healthy subjects
-
Abstract 89
-
Patel CG, Boulton DW, Brenner E. Effect of ketoconazole on the pharmacokinetics of saxagliptin in healthy subjects. J. Clin. Pharmacol. 47, 1183-1211 (2007) (Abstract 89).
-
(2007)
J. Clin. Pharmacol.
, vol.47
, pp. 1183-1211
-
-
Patel, C.G.1
Boulton, D.W.2
Brenner, E.3
-
37
-
-
78649371080
-
-
Onglyza™ Europe package insert Bristol-Myers Squibb, Princeton, NJ, USA, & AstraZeneca, Wilmington, DE, USA
-
Onglyza™ Europe, package insert. Bristol-Myers Squibb, Princeton, NJ, USA, & AstraZeneca, Wilmington, DE, USA.
-
-
-
-
38
-
-
42149194313
-
Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naïve patients with Type 2 diabetes
-
Rosenstock J, Sankoh S, List JF. Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naïve patients with Type 2 diabetes. Diabetes Obes. Metab. 10, 376-386 (2008).
-
(2008)
Diabetes Obes. Metab.
, vol.10
, pp. 376-386
-
-
Rosenstock, J.1
Sankoh, S.2
List, J.F.3
-
39
-
-
73449117555
-
Saxagliptin: A new DPP-4 inhibitor for the treatment of Type 2 diabetes mellitus
-
Tahrani AA, Piya MK, Barnett AH. Saxagliptin: a new DPP-4 inhibitor for the treatment of Type 2 diabetes mellitus. Adv. Ther. 26(3), 249-262 (2009).
-
(2009)
Adv. Ther.
, vol.26
, Issue.3
, pp. 249-262
-
-
Tahrani, A.A.1
Piya, M.K.2
Barnett, A.H.3
-
40
-
-
76349117322
-
Once daily saxagliptin added to metformin provides sustained glycemic control and is well tolerated over 102 weeks in patients with T2D
-
Abstract 547-P
-
DeFronzo R, Hissa MN, Garber AJ et al. Once daily saxagliptin added to metformin provides sustained glycemic control and is well tolerated over 102 weeks in patients with T2D. Diabetes 58(Suppl. 1), (2009) (Abstract 547-P).
-
(2009)
Diabetes
, vol.58
, Issue.SUPPL. 1
-
-
Defronzo, R.1
Hissa, M.N.2
Garber, A.J.3
-
41
-
-
78649360349
-
Effcacy and safety of saxagliptin 5 mg once-daily therapy in elderly patients with Type 2 diabetes mellitus
-
Maheux P, Doucet J, Allen E et al. Effcacy and safety of saxagliptin 5 mg once-daily therapy in elderly patients with Type 2 diabetes mellitus. Diabetologia 52, 1-550 (2008).
-
(2008)
Diabetologia
, vol.52
, pp. 1-550
-
-
Maheux, P.1
Doucet, J.2
Allen, E.3
-
42
-
-
10744221639
-
Thiazolidinedione use, fuid retention, and congestive heart failure: A consensus statement from the American Heart Association and American Diabetes Association
-
Nesto RW, Bell D, Bonow RO et al. Thiazolidinedione use, fuid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. Diabetes Care 27(1), 256-263 (2004).
-
(2004)
Diabetes Care
, vol.27
, Issue.1
, pp. 256-263
-
-
Nesto, R.W.1
Bell, D.2
Bonow, R.O.3
-
43
-
-
33846828660
-
Vildagliptin in combination with pioglitazone improves glycaemic control in patients with Type 2 diabetes failing thiazolidinedione monotherapy: A randomized, placebo-controlled study
-
Garber AJ, Schweizer A, Baron MA, Rochotte E, Dejager S. Vildagliptin in combination with pioglitazone improves glycaemic control in patients with Type 2 diabetes failing thiazolidinedione monotherapy: a randomized, placebo-controlled study. Diabetes Obes. Metab. 9(2), 166-174 (2007).
-
(2007)
Diabetes Obes. Metab.
, vol.9
, Issue.2
, pp. 166-174
-
-
Garber, A.J.1
Schweizer, A.2
Baron, M.A.3
Rochotte, E.4
Dejager, S.5
-
44
-
-
79952714842
-
Saxagliptin used as monotherapy or in combination with other antihyperglycemic agents does not signifcantly increase risk of hypoglycemia
-
Chen R, Donovan M, Rusnak JM. Saxagliptin used as monotherapy or in combination with other antihyperglycemic agents does not signifcantly increase risk of hypoglycemia. Diabetes 58(Suppl. 1), A536 (2009).
-
(2009)
Diabetes
, vol.58 A536
, Issue.SUPPL. 1
-
-
Chen, R.1
Donovan, M.2
Rusnak, J.M.3
-
45
-
-
34547863123
-
Effcacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with Type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin
-
Hermansen K, Kipnes M, Luo E et al. Effcacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with Type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin. Diabetes Obes. Metab. 9(5), 733-745 (2007).
-
(2007)
Diabetes Obes. Metab.
, vol.9
, Issue.5
, pp. 733-745
-
-
Hermansen, K.1
Kipnes, M.2
Luo, E.3
-
46
-
-
54249106294
-
Effects of vildagliptin on glucose control in patients with Type 2 diabetes inadequately controlled with a sulphonylurea
-
Garber AJ, Foley JE, Banerji MA et al. Effects of vildagliptin on glucose control in patients with Type 2 diabetes inadequately controlled with a sulphonylurea. Diabetes Obes. Metab. 10(11), 1047-1056 (2008).
-
(2008)
Diabetes Obes. Metab.
, vol.10
, Issue.11
, pp. 1047-1056
-
-
Garber, A.J.1
Foley, J.E.2
Banerji, M.A.3
-
47
-
-
78649345796
-
-
Department of Health and Human Services Food and Drug Administration June
-
US Department of Health and Human Services. Food and Drug Administration. FDA Approval 22-350. June (2008).
-
(2008)
FDA Approval
, pp. 22-350
-
-
-
48
-
-
73449095647
-
Single-dose pharmacokinetics and safety of saxagliptin in subjects with hepatic impairment compared with healthy subjects
-
Abstract A160
-
Patel C, Castaneda L, Frevert U et al. Single-dose pharmacokinetics and safety of saxagliptin in subjects with hepatic impairment compared with healthy subjects. Diabetes 57(Suppl. 1), (2008) (Abstract A160).
-
(2008)
Diabetes
, vol.57
, Issue.SUPPL. 1
-
-
Patel, C.1
Castaneda, L.2
Frevert, U.3
-
49
-
-
77958030736
-
Effcacy and safety of saxagliptin in combination with metformin compared with sitagliptin in combination with metformin in adult patients with Type 2 diabetes mellitus
-
Scheen AY, Charpentier G, Östgren CJ, Hellqvist Å, Gause-Nilsson I. Effcacy and safety of saxagliptin in combination with metformin compared with sitagliptin in combination with metformin in adult patients with Type 2 diabetes mellitus. Diabetes Metab. Res. Rev. 26(7), 540-549 (2010).
-
(2010)
Diabetes Metab. Res. Rev.
, vol.26
, Issue.7
, pp. 540-549
-
-
Scheen, A.Y.1
Charpentier, G.2
Östgren, C.J.3
Hellqvist, Å.4
Gause-Nilsson, I.5
-
50
-
-
0036298693
-
Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1
-
Hinke SA, Kühn-Wache K, Hoffmann T et al. Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1. Biochem. Biophys. Res. Commun. 291(5), 1302-1308 (2002).
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.291
, Issue.5
, pp. 1302-1308
-
-
Hinke, S.A.1
Kühn-Wache, K.2
Hoffmann, T.3
-
51
-
-
55549136417
-
Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: A randomized, cross-over study
-
DeFronzo RA, Okerson T, Viswanathan P et al. Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study. Curr. Med. Res. Opin. 24(10), 2943-2952 (2008).
-
(2008)
Curr. Med. Res. Opin.
, vol.24
, Issue.10
, pp. 2943-2952
-
-
Defronzo, R.A.1
Okerson, T.2
Viswanathan, P.3
-
52
-
-
34248169217
-
Effects of dipeptidyl peptidase-4 inhibition on gastrointestinal function, meal appearance, and glucose metabolism in Type 2 diabetes
-
Vella A, Bock G, Giesler PD et al. Effects of dipeptidyl peptidase-4 inhibition on gastrointestinal function, meal appearance, and glucose metabolism in Type 2 diabetes. Diabetes 56(5), 1475-1480 (2007).
-
(2007)
Diabetes
, vol.56
, Issue.5
, pp. 1475-1480
-
-
Vella, A.1
Bock, G.2
Giesler, P.D.3
|