메뉴 건너뛰기




Volumn 8, Issue 10, 2010, Pages 2334-2338

Is there really a relationship between the plasma concentration of the active metabolite of clopidogrel and the results of platelet function tests?

Author keywords

[No Author keywords available]

Indexed keywords

CLOPIDOGREL; DRUG METABOLITE; VASODILATOR STIMULATED PHOSPHOPROTEIN;

EID: 78649363570     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2010.04004.x     Document Type: Letter
Times cited : (11)

References (26)
  • 1
    • 34547655744 scopus 로고    scopus 로고
    • ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardio-vascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine
    • Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, Chavey WE 2nd, Fesmire FM, Hochman JS, Levin TN, Lincoff AM, Peterson ED, Theroux P, Wenger NK, Wright RS, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardio-vascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. J Am Coll Cardiol 2007; 50: e1-157.
    • (2007) J Am Coll Cardiol , vol.50
    • Anderson, J.L.1    Adams, C.D.2    Antman, E.M.3    Bridges, C.R.4    Califf, R.M.5    Casey D.E., Jr.6    Chavey W.E. 2nd7    Fesmire, F.M.8    Hochman, J.S.9    Levin, T.N.10    Lincoff, A.M.11    Peterson, E.D.12    Theroux, P.13    Wenger, N.K.14    Wright, R.S.15    Smith S.C., Jr.16    Jacobs, A.K.17    Adams, C.D.18    Anderson, J.L.19    Antman, E.M.20    more..
  • 3
    • 70450199115 scopus 로고    scopus 로고
    • 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • Kushner FG, Hand M, Smith SC Jr, King SB 3rd, Anderson JL, Antman EM, Bailey SR, Bates ER, Blankenship JC, Casey DE Jr, Green LA, Hochman JS, Jacobs AK, Krumholz HM, Morrison DA, Ornato JP, Pearle DL, Peterson ED, Sloan MA, Whitlow PL et al. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2009; 54: 2205-41.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 2205-2241
    • Kushner, F.G.1    Hand, M.2    Smith S.C., Jr.3    King S.B. 3rd4    Anderson, J.L.5    Antman, E.M.6    Bailey, S.R.7    Bates, E.R.8    Blankenship, J.C.9    Casey D.E., Jr.10    Green, L.A.11    Hochman, J.S.12    Jacobs, A.K.13    Krumholz, H.M.14    Morrison, D.A.15    Ornato, J.P.16    Pearle, D.L.17    Peterson, E.D.18    Sloan, M.A.19    Whitlow, P.L.20    more..
  • 4
    • 58749090547 scopus 로고    scopus 로고
    • French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) Investigators. Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, Quteineh L, Drouet E, Méneveau N, Steg PG, Ferrières J, Danchin N, Becquemont L.; French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) Investigators. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med 2009; 360: 363-75.
    • (2009) N Engl J Med , vol.360 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3    Quteineh, L.4    Drouet, E.5    Méneveau, N.6    Steg, P.G.7    Ferrières, J.8    Danchin, N.9    Becquemont, L.10
  • 5
    • 34447576539 scopus 로고    scopus 로고
    • Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: a systematic review and meta-analysis
    • Snoep JD, Hovens MM, Eikenboom JC, van der Bom JG, Jukema JW, Huisman MV. Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: a systematic review and meta-analysis. Am Heart J 2007; 154: 221-31.
    • (2007) Am Heart J , vol.154 , pp. 221-231
    • Snoep, J.D.1    Hovens, M.M.2    Eikenboom, J.C.3    van der Bom, J.G.4    Jukema, J.W.5    Huisman, M.V.6
  • 6
    • 67649372663 scopus 로고    scopus 로고
    • Assessment, mechanisms, and clinical implication of variability in platelet response to aspirin and clopidogrel therapy
    • Ben-Dor I, Kleiman NS, Lev E. Assessment, mechanisms, and clinical implication of variability in platelet response to aspirin and clopidogrel therapy. Am J Cardiol 2009; 104: 227-33.
    • (2009) Am J Cardiol , vol.104 , pp. 227-233
    • Ben-Dor, I.1    Kleiman, N.S.2    Lev, E.3
  • 9
    • 56849130022 scopus 로고    scopus 로고
    • Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo
    • Erlinge D, Varenhorst C, Braun OO, James S, Winters KJ, Jakubowski JA, Brandt JT, Sugidachi A, Siegbahn A, Wallentin L. Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo. J Am Coll Cardiol 2008; 52: 1968-77.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1968-1977
    • Erlinge, D.1    Varenhorst, C.2    Braun, O.O.3    James, S.4    Winters, K.J.5    Jakubowski, J.A.6    Brandt, J.T.7    Sugidachi, A.8    Siegbahn, A.9    Wallentin, L.10
  • 10
    • 37849002889 scopus 로고    scopus 로고
    • Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
    • Wallentin L, Varenhorst C, James S, Erlinge D, Braun OO, Jakubowski JA, Sugidachi A, Winters KJ, Siegbahn A. Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease. Eur Heart J 2008; 29: 21-30.
    • (2008) Eur Heart J , vol.29 , pp. 21-30
    • Wallentin, L.1    Varenhorst, C.2    James, S.3    Erlinge, D.4    Braun, O.O.5    Jakubowski, J.A.6    Sugidachi, A.7    Winters, K.J.8    Siegbahn, A.9
  • 11
    • 33845451677 scopus 로고    scopus 로고
    • A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation
    • Brandt JT, Payne CD, Wiviott SD, Weerakkody G, Farid NA, Small DS, Jakubowski JA, Naganuma H, Winters KJ. A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation. Am Heart J 2007; 153: 66.e9-16.
    • (2007) Am Heart J , vol.153 , Issue.66
    • Brandt, J.T.1    Payne, C.D.2    Wiviott, S.D.3    Weerakkody, G.4    Farid, N.A.5    Small, D.S.6    Jakubowski, J.A.7    Naganuma, H.8    Winters, K.J.9
  • 12
    • 57549090390 scopus 로고    scopus 로고
    • Clopidogrel 150 mg/day to overcome low responsiveness in patients undergoing elective percutaneous coronary intervention: results from the VASP-02 (Vasodilator-Stimulated Phosphoprotein-02) randomized study
    • Aleil B, Jacquemin L, DePoli F, Zaehringer M, Collet JP, Montalescot G, Cazenave JP, Dickele MC, Monassier JP, Gachet C. Clopidogrel 150 mg/day to overcome low responsiveness in patients undergoing elective percutaneous coronary intervention: results from the VASP-02 (Vasodilator-Stimulated Phosphoprotein-02) randomized study. JACC Cardiovasc Interv 2008; 1: 631-8.
    • (2008) JACC Cardiovasc Interv , vol.1 , pp. 631-638
    • Aleil, B.1    Jacquemin, L.2    DePoli, F.3    Zaehringer, M.4    Collet, J.P.5    Montalescot, G.6    Cazenave, J.P.7    Dickele, M.C.8    Monassier, J.P.9    Gachet, C.10
  • 13
    • 71949115114 scopus 로고    scopus 로고
    • Relation of body mass index to high on-treatment platelet reactivity and of failed clopidogrel dose adjustment according to platelet reactivity monitoring in patients undergoing percutaneous coronary intervention
    • Bonello-Palot N, Armero S, Paganelli F, Mancini J, De Labriolle A, Bonello C, Lévy N, Maillard L, Barragan P, Dignat-George F, Camoin-Jau L, Bonello L. Relation of body mass index to high on-treatment platelet reactivity and of failed clopidogrel dose adjustment according to platelet reactivity monitoring in patients undergoing percutaneous coronary intervention. Am J Cardiol 2009; 104: 1511-15.
    • (2009) Am J Cardiol , vol.104 , pp. 1511-1515
    • Bonello-Palot, N.1    Armero, S.2    Paganelli, F.3    Mancini, J.4    De Labriolle, A.5    Bonello, C.6    Lévy, N.7    Maillard, L.8    Barragan, P.9    Dignat-George, F.10    Camoin-Jau, L.11    Bonello, L.12
  • 14
    • 74049095574 scopus 로고    scopus 로고
    • Aspirin and clopidogrel hyporesponsiveness and nonresponsiveness in patients with coronary artery stenting
    • Sharma RK, Reddy HK, Singh VN, Sharma R, Voelker DJ, Bhatt G. Aspirin and clopidogrel hyporesponsiveness and nonresponsiveness in patients with coronary artery stenting. Vasc Health Risk Manag 2009; 5: 965-72.
    • (2009) Vasc Health Risk Manag , vol.5 , pp. 965-972
    • Sharma, R.K.1    Reddy, H.K.2    Singh, V.N.3    Sharma, R.4    Voelker, D.J.5    Bhatt, G.6
  • 17
    • 78649350669 scopus 로고    scopus 로고
    • Plavix (Clopidogrel Bisulfate). Label information. Accessed 12 March
    • Plavix (Clopidogrel Bisulfate). Label information. http://www.accessdata.fda.gov/drugsatfda_docs/label/2010/020839s042lbl.pdf. Accessed 12 March 2010.
    • (2010)
  • 18
    • 70749149366 scopus 로고    scopus 로고
    • Clopidogrel pharmacogenomics and risk of inadequate platelet inhibition: US FDA recommendations
    • Ellis KJ, Stouger GA, McLeod HL, Lee CR. Clopidogrel pharmacogenomics and risk of inadequate platelet inhibition: US FDA recommendations. Pharmacogenomics 2009; 10: 1799-817.
    • (2009) Pharmacogenomics , vol.10 , pp. 1799-1817
    • Ellis, K.J.1    Stouger, G.A.2    McLeod, H.L.3    Lee, C.R.4
  • 19
    • 70350025236 scopus 로고    scopus 로고
    • P2C19*2 polymorphism is not the sole determinant of the response to clopidogrel: implications for its monitoring
    • Aleil B, Léon C, Cazenave JP, Gachet C. P2C19*2 polymorphism is not the sole determinant of the response to clopidogrel: implications for its monitoring. J Thromb Haemost 2009; 7: 1747-9.
    • (2009) J Thromb Haemost , vol.7 , pp. 1747-1749
    • Aleil, B.1    Léon, C.2    Cazenave, J.P.3    Gachet, C.4
  • 20
    • 68949130179 scopus 로고    scopus 로고
    • P2Y(12) inhibitors: differences in properties and mechanisms of action and potential consequences for clinical use
    • Wallentin L. P2Y(12) inhibitors: differences in properties and mechanisms of action and potential consequences for clinical use. Eur Heart J 2009; 30: 1964-77.
    • (2009) Eur Heart J , vol.30 , pp. 1964-1977
    • Wallentin, L.1
  • 21
    • 57849099154 scopus 로고    scopus 로고
    • Quantitative determination of clopidogrel active metabolite in human plasma by LC-MS/MS
    • Takahashi M, Pang H, Kawabata K, Farid NA, Kurihara A. Quantitative determination of clopidogrel active metabolite in human plasma by LC-MS/MS. J Pharm Biomed Anal 2008; 48: 1219-24.
    • (2008) J Pharm Biomed Anal , vol.48 , pp. 1219-1224
    • Takahashi, M.1    Pang, H.2    Kawabata, K.3    Farid, N.A.4    Kurihara, A.5
  • 22
    • 77949297362 scopus 로고    scopus 로고
    • Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel
    • Bouman HJ, Parlak E, van Werkum JW, Breet NJ, ten Cate H, Hackeng CM, ten Berg JM, Taubert D. Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel. J Thromb Haemost 2010; 8: 482-8.
    • (2010) J Thromb Haemost , vol.8 , pp. 482-488
    • Bouman, H.J.1    Parlak, E.2    van Werkum, J.W.3    Breet, N.J.4    ten Cate, H.5    Hackeng, C.M.6    ten Berg, J.M.7    Taubert, D.8
  • 24
    • 42249102617 scopus 로고    scopus 로고
    • P2 receptors, platelet function and pharmacological implications
    • Gachet C. P2 receptors, platelet function and pharmacological implications. Thromb Haemost 2008; 99: 466-72.
    • (2008) Thromb Haemost , vol.99 , pp. 466-472
    • Gachet, C.1
  • 26
    • 18144371221 scopus 로고    scopus 로고
    • The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting
    • Gurbel PA, Bliden KP, Hayes KM, Yoho JA, Herzog WR, Tantry US. The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting. J Am Coll Cardiol 2005; 45: 1392-6.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1392-1396
    • Gurbel, P.A.1    Bliden, K.P.2    Hayes, K.M.3    Yoho, J.A.4    Herzog, W.R.5    Tantry, U.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.