Transiently increased endothelial layer permeability by ultrasound-activated microbubbles

Proceedings - IEEE Ultrasonics Symposium

Volumn 1, Issue , 2006, Pages 529-531

  Kooiman, Klazina ^a   Harteveld, Miranda ^a   De Jong, Nico ^a,b,c   Van Wamel, Annemieke ^a,b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^c UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Contrast agent; Drug delivery; Endothelial permeability; Ultrasound

Indexed keywords

AFTER-TREATMENT; CELL LOSS; CONTRAST AGENT; DRUG DELIVERY SYSTEM; ELECTRICAL RESISTANCES; ENDOTHELIAL PERMEABILITY; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; INITIAL VALUES; MICROBUBBLES; ULTRASOUND;

CELL MEMBRANES; CONTROLLED DRUG DELIVERY; CYTOLOGY; SELF ASSEMBLY; ULTRASONICS;

ENDOTHELIAL CELLS;

EID: 78649346524     PISSN: 10510117     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/ULTSYM.2006.138     Document Type: Conference Paper

References (15)

1. J.R. Gudgeon and W. Martin, "Modulation of arterial endothelial permeability: studies on an in vitro model," Br. J. Pharmacol., vol. 98, pp. 1267-1274, 1989.
2. G.P. van Nieuw Amerongen, V.W.M. van Hinsbergh, "Targets for pharmacological intervention of endothelial hyperpermeability and barrier function," Vasc. Pharmacol., vol. 39, pp. 257-272, 2002.
3. D.J. Morgan, "Permeability of myocardial capillaries to hydrophylic drugs: the paracellular pathway," Clin. Exp. Pharmacol. Physiol., vol. 23, pp. 975-979, 1996.
4. H. Pan, Y. Zhou, O. Izadnegahdar, J. Cui, and C.X. Deng, "Study of sonoporation dynamics affected by ultrasound duty cycle," Ultrasound Med. Biol., vol. 31, pp. 849-856, 2005.
5. S.M. Mehier-Humbert, T. Bettinger, F. Yan, and R.H. Guy, "Plasma membrane poration induced by ultrasound exposure: Implication for drug delivery," J. Contr. Release, vol. 104, pp. 213-222, 2005.
6. A. van Wamel, K. Kooiman, M. Harteveld, M. Emmer, F.J. ten Cate, M. Versluis, and N. de Jong, "Vibrating microbubbles poking individual cells: Drug transfer into cells via sonoporatio," J. Contr. Release, vol. 112, pp. 149-155, 2006.
7. A. van Wamel, A. Bouakaz, B. Bernard, F. ten Cate, and N. de Jong, "Radionuclide tumour therapy with ultrasound contrast microbubbles Ultrasonics, vol. 42, pp. 903-906, 2004.
8. N. Gautam, P. Hedqvist, and L. Lindbom, "Kinetics of leukocyte-induced changes in endothelial barrier function," Br. J. Pharmacol., vol. 125, pp. 1109-1114, 1998.
9. P.G. Bannon, M-J. Kim, R.T. Dean, and J. Dawes, "Augmentation of vascular endothelial barrier function by heparin and low molecular weight heparin," Thromb. Haemost., vol. 73, pp. 706-712, 1995.
10. M.H. Ali, S.A. Schlidt, N.S. Chandel, K.L. Hynes, P.T. Schumacher, and B.L. Gewertz, "Endothelial permeability and IL-6 production during hypoxia: role of ROS in signal transduction," Am. J. Phsyiol., vol. 277, pp. L1057-L1065, 1999.
11. B.E. Dewi, T. takasaki, and I. Kurane, "In vitro assessment of human endothelial cell permeability: effects of inflammatory cytokines and dengue virus infection," J. Virol. Methods, vol. 121, pp. 171-180, 2004.
12. E. Dejana, and A. Del Maschio, "Molecular organization and functional regulation of cell to cell junctions in the endothelium," Thromb. Haemost., vol. 74, pp. 309-312, 1995.
13. A.L. Klibanov, "Microbubble contrast agents. Targeted ultrasound imaging and ultrasound-assisted drug-delivery applications," Invest. Radiol., vol. 41, pp. 354-362, 2006.
14. F. Brunstein, S. Hoving, A.L.B. Seynhave, S.T. van Tiel, G. Guetens, E.A. de Bruijn, A.M.M. Eggermont, and T.L.M. ten Hagen, "Synergistic antitumor activity of histamine plus melphalan in isolated limb perfusion: preclinical studies," J. Natl. Cancer Inst., vol. 96, pp. 1603-1610, 2004.
15. S. Hoving, F. Brunstein, G. aan de Wiel-Ambagtsheer, S.T. van Tiel, G. de Boeck, E.A. de Bruijn, A.M.M. Eggermont, and T.L.M. ten Hagen, "Synergistic antitumor response of interleukin 2 with melphalan in isolated limb perfusion in soft tissue sarcoma-bearing rats," Cancer Res., vol. 65, pp. 4300-4308, 2005.