Prevalence and clinical significance of hepatitis b basal core promoter and precore gene mutations in southern iranian patients

Hepatitis Monthly

Volumn 10, Issue 4, 2010, Pages 294-297

  Taghavi, Seyed Alireza ^a   Tabibi, Manouchehr ^a   Eshraghian, Ahad ^a   Keyvani, Hossein ^b   Eshraghian, Hamed ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Basal core mutation; Hepatitis b virus; Iran; Precore mutation

Indexed keywords

ALANINE AMINOTRANSFERASE; CORE PROTEIN; HEPATITIS B(E) ANTIBODY; HEPATITIS B(E) ANTIGEN; LIVER ENZYME;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; FEMALE; GENE MUTATION; GENOTYPE; HEPATITIS B; HEPATITIS C; HUMAN; IRAN; LABORATORY TEST; MALE; PATIENT REFERRAL; PHENOTYPE; PREVALENCE; PROMOTER REGION; UNIVERSITY HOSPITAL;

EID: 78649338255     PISSN: 1735143X     EISSN: 17353408     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Lee WM. Hepatitis B virus infection. N Engl J Med. 1997;337(24):1733-45.
2. Okamoto H, Tsuda F, Sakugawa H, et al. Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes. J Gen Virol. 1988;69 (Pt 10):2575-83.
3. Westland C, Delaney Wt, Yang H, et al. Hepatitis B virus genotypes and virologic response in 694 patients in phase III studies of adefovir dipivoxil1. Gastroenterology. 2003;125(1):107-16.
4. Miyakawa Y, Mizokami M. Classifying hepatitis B virus genotypes. Intervirology. 2003;46(6):329-38.
5. Kao JH, Chen PJ, Lai MY, Chen DS. Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers. Gastroenterology. 2003;124(2):327-34.
6. Abdo AA, Al-Jarallah BM, Sanai FM, et al. Hepatitis B genotypes: relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia. World J Gastroenterol. 2006;12(43):7019-24.
7. Amini-Bavil-Olyaee S, Sarrami-Forooshani R, Mahboudi F, et al. Genotype characterization and phylogenetic analysis of hepatitis B virus isolates from Iranian patients. J Med Virol. 2005;75(2):227-34.
8. Kao JH, Liu CJ, Chen DS. Hepatitis B viral genotypes and lamivudine resistance. J Hepatol. 2002;36(2):303-4.
9. Hunt CM, McGill JM, Allen MI, Condreay LD. Clinical relevance of hepatitis B viral mutations. Hepatology. 2000;31(5):1037-44.
10. Chen BF, Liu CJ, Jow GM, Chen PJ, Kao JH, Chen DS. High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases. Gastroenterology. 2006;130(4):1153-68.
11. Naoumov NV, Schneider R, Grotzinger T, et al. Precore mutant hepatitis B virus infection and liver disease. Gastroenterology. 1992;102(2):538-43.
12. Scaglioni PP, Melegari M, Wands JR. Biologic properties of hepatitis B viral genomes with mutations in the precore promoter and precore open reading frame. Virology. 1997;233(2):374-81.
13. Lin CL, Liao LY, Liu CJ, et al. Hepatitis B genotypes and precore/basal core promoter mutants in HBeAg-negative chronic hepatitis B. J Gastroenterol. 2002;37(4):283-7.
14. Tong MJ, Blatt LM, Kao JH, Cheng JT, Corey WG. Basal core promoter T1762/A1764 and precore A1896 gene mutations in hepatitis B surface antigen-positive hepatocellular carcinoma: a comparison with chronic carriers. Liver Int. 2007;27(10):1356-63.