The local vasoconstriction of infant's skin following instillation of mydriatic eye drops

European Journal of Clinical Pharmacology

Volumn 66, Issue 11, 2010, Pages 1161-1164

  Alpay, Atilla ^a   Ermis, Bahri ^a   Ugurbas, Silay C ^a   Battal, Fatih ^a   Sagdik, Haci Murat ^a  

^a ZONGULDAK KARAELMAS UNIVERSITY   (Turkey)

Author keywords

Eye drops; Infants; Paleness; Systemic absorption

Indexed keywords

PHENYLEPHRINE; TROPICAMIDE;

ARTICLE; CASE REPORT; EYE EXAMINATION; HUMAN; INFANT; OPHTHALMOSCOPY; PALLOR; PREMATURITY; PRIORITY JOURNAL; RETINOPATHY; SKIN DISCOLORATION;

HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MYDRIATICS; OPHTHALMIC SOLUTIONS; PALLOR; PHENYLEPHRINE; RETINOPATHY OF PREMATURITY; SKIN; TIME FACTORS; TROPICAMIDE; VASOCONSTRICTION;

EID: 78649331068     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-010-0890-6     Document Type: Article

References (23)

1. C Chew RA Rahman SM Shafie Z Mohamad 2005 Comparison of mydriatic regimens used in screening for retinopathy of prematurity in preterm infants with dark irides J Pediatr Ophthalmol Strabismus 42 166 173 15977870
2. AR Wilkinson L Haines K Head AR Fielder 2009 UK retinopathy of prematurity guideline Eye (Lond) 23 2137 2139 1:STN:280:DC%2BD1MjltVelug%3D%3D
3. DS Chien JJ Homsy C Gluchowski DD Tang-Liu 1990 Corneal and conjunctival/scleral penetration of p-aminoclonidine, AGN 190342, and clonidine in rabbit eyes Curr Eye Res 9 1051 1059 1:STN:280:DyaK3M3kvFKksQ%3D%3D 10.3109/02713689008997579 1982760
4. T Shwayder T Akland 2005 Neonatal skin barrier: structure, function, and disorders Dermatol Ther 18 87 103 10.1111/j.1529-8019.2005.05011.x 15953139 (Pubitemid 40934403)
5. YN Kalia LB Nonato CH Lund RH Guy 1998 Development of skin barrier function in premature infants J Invest Dermatol 111 320 326 1:CAS:528: DyaK1cXltFGgtLg%3D 10.1046/j.1523-1747.1998.00289.x 9699737 (Pubitemid 28354723)
6. AJ Mancini 2004 Skin Pediatrics 113 1114 1119 15060207
7. N Sekkat YN Kalia RH Guy 2004 Development of an in vitro model for premature neonatal skin: biophysical characterization using transepidermal water loss J Pharm Sci 93 2936 2940 1:CAS:528:DC%2BD2cXhtVKlsrrP 10.1002/jps.20195 15459948 (Pubitemid 39657797)
8. JW Shell 1982 Pharmacokinetics of topically applied ophthalmic drugs Surv Ophthalmol 26 207 218 1:CAS:528:DyaL38XhtlGisb0%3D 10.1016/0039-6257(82)90081-9 7041308
9. KT Kwon AA Kazzi 2002 Second place winner. Absorption of topical ophthalmic medications presenting as lethargy and apnea in an infant J Emerg Med 23 371 374 10.1016/S0736-4679(02)00601-7 12480017 (Pubitemid 35449749)
10. R Rush S Rush J Nicolau K Chapman M Naqvi 2004 Systemic manifestations in response to mydriasis and physical examination during screening for retinopathy of prematurity Retina 24 242 245 10.1097/00006982-200404000-00009 15097885 (Pubitemid 38509611)
11. SU Sarici M Yurdakok S Unal 2001 Acute gastric dilatation complicating the use of mydriatics in a preterm newborn Pediatr Radiol 31 581 583 1:STN:280:DC%2BD3MrgtFGhsg%3D%3D 10.1007/s002470100498 11550771 (Pubitemid 32734283)
12. BD Sindel MD Baker MJ Maisels J Weinstein 1986 A comparison of the pupillary and cardiovascular effects of various mydriatic agents in preterm infants J Pediatr Ophthalmol Strabismus 23 273 276 1:STN:280: DyaL1czgtVektg%3D%3D 3454368
13. AJ Patel JW Simon DJ Hodgetts 2004 Cycloplegic and mydriatic agents for routine ophthalmologic examination: a survey of pediatric ophthalmologists J AAPOS 8 274 277 10.1016/j.jaapos.2004.01.004 15226730 (Pubitemid 38833745)
14. C Gray 2006 Systemic toxicity with topical ophthalmic medications in children Paed Perinat Drug Ther 7 23 29 10.1185/146300905X75334
15. MS Ogut N Bozkurt E Ozek H Birgen H Kazokoglu M Ogut 1996 Effects and side effects of mydriatic eyedrops in neonates Eur J Ophthalmol 6 192 196 1:STN:280:DyaK28vitVyquw%3D%3D 8823596
16. Hardman JG, Gilman AG, Limbird LE (1996) Goodman & Gilman's The pharmacological basis of therapeutics, 9th edn. McGraw Hill, New York, pp 529-531
17. JG Lawrenson R Birhah PJ Murphy 2005 Tear-film lipid layer morphology and corneal sensation in the development of blinking in neonates and infants J Anat 206 265 270 10.1111/j.1469-7580.2005.00386.x 15733299 (Pubitemid 40424846)
18. O Elibol T Alcelik N Yuksel Y Caglar 1997 The influence of drop size of cyclopentolate, phenylephrine and tropicamide on pupil dilatation and systemic side effects in infants Acta Ophthalmol Scand 75 178 180 1:CAS:528: DyaK2sXjvF2nu78%3D 10.1111/j.1600-0420.1997.tb00119.x 9197568
19. Isenberg SJ (1994) Physical and refractive characteristics of the eye at birth and during infancy. In: St.Louis (ed) The eye in infancy, 2nd edn. Mosby, Chicago, pp 36-51
20. I Akman U Demirel O Yenice H Ilerisoy H Kazokoglu E Ozek 2010 Screening criteria for retinopathy of prematurity in developing countries Eur J Ophthalmol 20 931 937 20383846
21. CS Ling BW Fleck E Wright C Anderson I Laing 1995 Diode laser treatment for retinopathy of prematurity: structural and functional outcome Br J Ophthalmol 79 637 641 1:STN:280:DyaK2MzptFKitA%3D%3D 10.1136/bjo.79.7.637 7662625
22. R Brennan L Gnanaraj DG Cottrell 2003 Retinopathy of prematurity in practice. I: Screening for threshold disease Eye (Lond) 17 183 188 1:STN:280:DC%2BD3s7isFGrtQ%3D%3D
23. Royal College of Paediatrics & Child Health & Royal College of Opthalmologists (2008) UK retinopathy of prematurity guideline. http://www.rcophth.ac.uk/docs/scientific/Guideline-Retinopathy-of-Prematurity- 2008.pdf