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Volumn 62, Issue 11, 2010, Pages 1125-1138

Radionuclide probes for molecular imaging of pancreatic beta-cells

Author keywords

GLP 1 receptor; Neural imaging probes; Pancreatic beta cell imaging; PET; Radiolabeled antibody; Reporter gene; Saccharides; SPECT; Sulfonylurea receptor

Indexed keywords

BETA CELL; GLP-1 RECEPTOR; NEURAL IMAGING PROBES; PET; RADIOLABELED ANTIBODY; REPORTER GENE; SACCHARIDES; SPECT; SULFONYLUREA RECEPTORS;

EID: 78649325301     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2010.09.006     Document Type: Review
Times cited : (27)

References (122)
  • 1
    • 77952778090 scopus 로고    scopus 로고
    • General concept and pathophysiological mechanisms of progression of macrovascular complications in diabetes
    • Kashiwagi A. General concept and pathophysiological mechanisms of progression of macrovascular complications in diabetes. Nippon Rinsho 2010, 68:777-787.
    • (2010) Nippon Rinsho , vol.68 , pp. 777-787
    • Kashiwagi, A.1
  • 2
    • 77949829170 scopus 로고    scopus 로고
    • Diabetes and cardiovascular complications
    • Resl M., Clodi M. Diabetes and cardiovascular complications. Wien. Med. Wochenschr. 2010, 160:3-7.
    • (2010) Wien. Med. Wochenschr. , vol.160 , pp. 3-7
    • Resl, M.1    Clodi, M.2
  • 5
    • 77949382854 scopus 로고    scopus 로고
    • Neuroprotection in diabetic encephalopathy
    • Fazeli S.A. Neuroprotection in diabetic encephalopathy. Neurodegener. Dis. 2009, 6:213-218.
    • (2009) Neurodegener. Dis. , vol.6 , pp. 213-218
    • Fazeli, S.A.1
  • 6
    • 77956212237 scopus 로고    scopus 로고
    • MR imaging of pancreatic islets: tracking isolation, transplantation and function
    • Leoni L., Roman B.B. MR imaging of pancreatic islets: tracking isolation, transplantation and function. Curr. Pharm. Des. 2010, 16:1582-1594.
    • (2010) Curr. Pharm. Des. , vol.16 , pp. 1582-1594
    • Leoni, L.1    Roman, B.B.2
  • 7
    • 70349200931 scopus 로고    scopus 로고
    • MRI as a tool to monitor islet transplantation
    • Medarova Z., Moore A. MRI as a tool to monitor islet transplantation. Nat. Rev. 2009, 5:444-452.
    • (2009) Nat. Rev. , vol.5 , pp. 444-452
    • Medarova, Z.1    Moore, A.2
  • 13
    • 33646756182 scopus 로고    scopus 로고
    • A novel method of monitoring response to islet transplantation: bioluminescent imaging of an NF-?B transgenic mouse model
    • Roth D.J., Jansen E.D., Powers A.C., Wang T.G. A novel method of monitoring response to islet transplantation: bioluminescent imaging of an NF-?B transgenic mouse model. Transplantation 2006, 81:1185-1190.
    • (2006) Transplantation , vol.81 , pp. 1185-1190
    • Roth, D.J.1    Jansen, E.D.2    Powers, A.C.3    Wang, T.G.4
  • 14
    • 23844558614 scopus 로고    scopus 로고
    • Bioluminescence imaging of nuclear calcium oscillations in intact pancreatic islets of Langerhans from the mouse
    • Villalobos C., Nadal A., Nunez L., Quesada I., Chamero P., Alonso M.T., Garcia-Sancho J. Bioluminescence imaging of nuclear calcium oscillations in intact pancreatic islets of Langerhans from the mouse. Cell Calcium 2005, 38:131-139.
    • (2005) Cell Calcium , vol.38 , pp. 131-139
    • Villalobos, C.1    Nadal, A.2    Nunez, L.3    Quesada, I.4    Chamero, P.5    Alonso, M.T.6    Garcia-Sancho, J.7
  • 15
    • 0027432681 scopus 로고
    • Evidence for release of free glucose from muscle during amylin-induced glycogenolysis in rats
    • Young A.A., Carlo P., Smith P., Wolfe-Lopez D., Pittner R., Wang M.-W., Rink T. Evidence for release of free glucose from muscle during amylin-induced glycogenolysis in rats. FEBS Lett. 1993, 334:317-321.
    • (1993) FEBS Lett. , vol.334 , pp. 317-321
    • Young, A.A.1    Carlo, P.2    Smith, P.3    Wolfe-Lopez, D.4    Pittner, R.5    Wang, M.-W.6    Rink, T.7
  • 18
    • 0035064221 scopus 로고    scopus 로고
    • On the track to the beta-cell
    • Malaisse W.J. On the track to the beta-cell. Diabetologia 2001, 44:393-406.
    • (2001) Diabetologia , vol.44 , pp. 393-406
    • Malaisse, W.J.1
  • 27
    • 0035430159 scopus 로고    scopus 로고
    • Uptake of tritiated d-mannoheptulose by liver, pancreatic exocrine and endocrine cells
    • Crenier L., Courtois P., Malaisse W.J. Uptake of tritiated d-mannoheptulose by liver, pancreatic exocrine and endocrine cells. Int. J. Mol. Med. 2001, 8:155-157.
    • (2001) Int. J. Mol. Med. , vol.8 , pp. 155-157
    • Crenier, L.1    Courtois, P.2    Malaisse, W.J.3
  • 33
    • 0027871067 scopus 로고
    • 11C]methoxy derivative of alpha-dihydrotetrabenazine: a radioligand for studying the vesicular monoamine transporter
    • 11C]methoxy derivative of alpha-dihydrotetrabenazine: a radioligand for studying the vesicular monoamine transporter. Appl. Radiat. Isot. 1993, 44:1487-1489.
    • (1993) Appl. Radiat. Isot. , vol.44 , pp. 1487-1489
    • DaSilva, J.N.1    Kilbourn, M.R.2    Mangner, T.J.3
  • 37
    • 0042244323 scopus 로고    scopus 로고
    • Expression of the two isoforms of the vesicular monoamine transporter (VMAT1 and VMAT2) in the endocrine pancreas and pancreatic endocrine tumors
    • Anlauf M., Eissele R., Schafer M.K., Eiden L.E., Arnold R., Pauser U., Kloppel G., Weihe E. Expression of the two isoforms of the vesicular monoamine transporter (VMAT1 and VMAT2) in the endocrine pancreas and pancreatic endocrine tumors. J. Histochem. Cytochem. 2003, 51:1027-1040.
    • (2003) J. Histochem. Cytochem. , vol.51 , pp. 1027-1040
    • Anlauf, M.1    Eissele, R.2    Schafer, M.K.3    Eiden, L.E.4    Arnold, R.5    Pauser, U.6    Kloppel, G.7    Weihe, E.8
  • 43
    • 53549087496 scopus 로고    scopus 로고
    • VMAT2 quantitation by PET as a biomarker for beta-cell mass in health and disease
    • Freeby M., Goland R., Ichise M., Maffei A., Leibel R., Harris P. VMAT2 quantitation by PET as a biomarker for beta-cell mass in health and disease. Diab. Obes. Metab. 2008, 10(Suppl 4):98-108.
    • (2008) Diab. Obes. Metab. , vol.10 , Issue.SUPPL. 4 , pp. 98-108
    • Freeby, M.1    Goland, R.2    Ichise, M.3    Maffei, A.4    Leibel, R.5    Harris, P.6
  • 53
    • 0023022686 scopus 로고
    • Aromatic amino acids and pancreatic islet function: a comparison of l-tryptophan and l-5-hydroxytryptophan
    • Lindstrom P., Sehlin J. Aromatic amino acids and pancreatic islet function: a comparison of l-tryptophan and l-5-hydroxytryptophan. Mol. Cell. Endocrinol. 1986, 48:121-126.
    • (1986) Mol. Cell. Endocrinol. , vol.48 , pp. 121-126
    • Lindstrom, P.1    Sehlin, J.2
  • 54
    • 0030937436 scopus 로고    scopus 로고
    • Presence of DOPA decarboxylase and its localisation in adult rat pancreatic islet cells
    • Borelli M.I., Villar M.J., Orezzoli A., Gagliardino J.J. Presence of DOPA decarboxylase and its localisation in adult rat pancreatic islet cells. Diabetes Metab. 1997, 23:161-163.
    • (1997) Diabetes Metab. , vol.23 , pp. 161-163
    • Borelli, M.I.1    Villar, M.J.2    Orezzoli, A.3    Gagliardino, J.J.4
  • 55
    • 77956194939 scopus 로고    scopus 로고
    • Clinical PET imaging of insulinoma and beta-cell hyperplasia
    • [Epub ahead of print]
    • Kauhanen S., Seppanen M., Minn H., Nuutila P. Clinical PET imaging of insulinoma and beta-cell hyperplasia. Curr. Pharm. Des. 2010, [Epub ahead of print].
    • (2010) Curr. Pharm. Des.
    • Kauhanen, S.1    Seppanen, M.2    Minn, H.3    Nuutila, P.4
  • 65
    • 0028964653 scopus 로고
    • Fluorinated benzamide neuroleptics-III. Development of (S)-N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-2, 3-dimethoxybenzamide as an improved dopamine D-2 receptor tracer
    • Mukherjee J., Yang Z.Y., Das M.K., Brown T. Fluorinated benzamide neuroleptics-III. Development of (S)-N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-2, 3-dimethoxybenzamide as an improved dopamine D-2 receptor tracer. Nucl. Med. Biol. 1995, 22:283-296.
    • (1995) Nucl. Med. Biol. , vol.22 , pp. 283-296
    • Mukherjee, J.1    Yang, Z.Y.2    Das, M.K.3    Brown, T.4
  • 68
  • 70
    • 0018241397 scopus 로고
    • Sulfonylurea drugs: mechanism of antidiabetic action and therapeutic usefulness
    • Lebovitz H.E., Feinglos M.N. Sulfonylurea drugs: mechanism of antidiabetic action and therapeutic usefulness. Diab. Care 1978, 1:189-198.
    • (1978) Diab. Care , vol.1 , pp. 189-198
    • Lebovitz, H.E.1    Feinglos, M.N.2
  • 72
    • 0020959045 scopus 로고
    • Metabolic effects of sulfonylurea drugs. A review
    • Groop L. Metabolic effects of sulfonylurea drugs. A review. Ann. Clin. Res. 1983, 15(Suppl 37):16-20.
    • (1983) Ann. Clin. Res. , vol.15 , Issue.SUPPL. 37 , pp. 16-20
    • Groop, L.1
  • 73
    • 0021840516 scopus 로고
    • The sulphonylurea receptor may be an ATP-sensitive potassium channel
    • Sturgess N.C., Ashford M.L., Cook D.L., Hales C.N. The sulphonylurea receptor may be an ATP-sensitive potassium channel. Lancet 1985, 2:474-475.
    • (1985) Lancet , vol.2 , pp. 474-475
    • Sturgess, N.C.1    Ashford, M.L.2    Cook, D.L.3    Hales, C.N.4
  • 75
    • 0032885235 scopus 로고    scopus 로고
    • Structural requirements of sulphonylureas and analogues for interaction with sulphonylurea receptor subtypes
    • Meyer M., Chudziak F., Schwanstecher C., Schwanstecher M., Panten U. Structural requirements of sulphonylureas and analogues for interaction with sulphonylurea receptor subtypes. Br. J. Pharmacol. 1999, 128:27-34.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 27-34
    • Meyer, M.1    Chudziak, F.2    Schwanstecher, C.3    Schwanstecher, M.4    Panten, U.5
  • 76
    • 0025774069 scopus 로고
    • Characterization of the solubilized glibenclamide receptor in a hamster pancreatic beta-cell line, HIT T15
    • Niki I., Welsh M., Berggren P.O., Hubbard P., Ashcroft S.J. Characterization of the solubilized glibenclamide receptor in a hamster pancreatic beta-cell line, HIT T15. Biochem. J. 1991, 277(Pt 3):619-624.
    • (1991) Biochem. J. , vol.277 , Issue.PART 3 , pp. 619-624
    • Niki, I.1    Welsh, M.2    Berggren, P.O.3    Hubbard, P.4    Ashcroft, S.J.5
  • 77
    • 0023833530 scopus 로고
    • Characterization of the sulfonylurea receptor on beta cell membranes
    • Gaines K.L., Hamilton S., Boyd A.E. Characterization of the sulfonylurea receptor on beta cell membranes. J. Biol. Chem. 1988, 263:2589-2592.
    • (1988) J. Biol. Chem. , vol.263 , pp. 2589-2592
    • Gaines, K.L.1    Hamilton, S.2    Boyd, A.E.3
  • 79
    • 0026653829 scopus 로고
    • Co-expression of sulfonylurea receptors and KATP channels in hamster insulinoma tumor (HIT) cells. Evidence for direct association of the receptor with the channel
    • Aguilar-Bryan L., Nichols C.G., Rajan A.S., Parker C., Bryan J. Co-expression of sulfonylurea receptors and KATP channels in hamster insulinoma tumor (HIT) cells. Evidence for direct association of the receptor with the channel. J. Biol. Chem. 1992, 267:14934-14940.
    • (1992) J. Biol. Chem. , vol.267 , pp. 14934-14940
    • Aguilar-Bryan, L.1    Nichols, C.G.2    Rajan, A.S.3    Parker, C.4    Bryan, J.5
  • 80
    • 0001546549 scopus 로고
    • Hypoglycemic activity in relation to chemical structure of potential oral antidiabetic substances. I. 1-Sulfonyl-3-alkylureas
    • Hoekfelt B., Joensson A. Hypoglycemic activity in relation to chemical structure of potential oral antidiabetic substances. I. 1-Sulfonyl-3-alkylureas. J. Med. Pharm. Chem. 1962, 51:231-239.
    • (1962) J. Med. Pharm. Chem. , vol.51 , pp. 231-239
    • Hoekfelt, B.1    Joensson, A.2
  • 85
  • 86
    • 33846807816 scopus 로고    scopus 로고
    • Synthesis and evaluation of a glibenclamide glucose-conjugate: a potential new lead compound for substituted glibenclamide derivatives as islet imaging agents
    • Schneider S., Ueberberg S., Korobeynikov A., Schechinger W., Schwanstecher C., Schwanstecher M., Klein H.H., Schirrmacher E. Synthesis and evaluation of a glibenclamide glucose-conjugate: a potential new lead compound for substituted glibenclamide derivatives as islet imaging agents. Regul. Pept. 2007, 139:122-127.
    • (2007) Regul. Pept. , vol.139 , pp. 122-127
    • Schneider, S.1    Ueberberg, S.2    Korobeynikov, A.3    Schechinger, W.4    Schwanstecher, C.5    Schwanstecher, M.6    Klein, H.H.7    Schirrmacher, E.8
  • 87
    • 0031892659 scopus 로고    scopus 로고
    • Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes
    • Fuhlendorff J., Rorsman P., Kofod H., Brand C.L., Rolin B., MacKay P., Shymko R., Carr R.D. Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes. Diabetes 1998, 47:345-351.
    • (1998) Diabetes , vol.47 , pp. 345-351
    • Fuhlendorff, J.1    Rorsman, P.2    Kofod, H.3    Brand, C.L.4    Rolin, B.5    MacKay, P.6    Shymko, R.7    Carr, R.D.8
  • 90
    • 18244428952 scopus 로고    scopus 로고
    • 18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET
    • 18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET. Nucl. Med. Biol. 1998, 25:175-180.
    • (1998) Nucl. Med. Biol. , vol.25 , pp. 175-180
    • Alauddin, M.M.1    Conti, P.S.2
  • 93
    • 4644294588 scopus 로고    scopus 로고
    • Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model
    • Alauddin M.M., Shahinian A., Gordon E.M., Conti P.S. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol. Imaging 2004, 3:76-84.
    • (2004) Mol. Imaging , vol.3 , pp. 76-84
    • Alauddin, M.M.1    Shahinian, A.2    Gordon, E.M.3    Conti, P.S.4
  • 94
    • 33645214648 scopus 로고    scopus 로고
    • 18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers
    • Buursma A.R., Rutgers V., Hospers G.A., Mulder N.H., Vaalburg W., de Vries E.F. 18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers. Nucl. Med. Commun. 2006, 27:25-30.
    • (2006) Nucl. Med. Commun. , vol.27 , pp. 25-30
    • Buursma, A.R.1    Rutgers, V.2    Hospers, G.A.3    Mulder, N.H.4    Vaalburg, W.5    de Vries, E.F.6
  • 95
    • 33745080072 scopus 로고    scopus 로고
    • Preclinical safety evaluation of 18F-FHBG: a PET reporter probe for imaging herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk's expression
    • Yaghoubi S.S., Couto M.A., Chen C.C., Polavaram L., Cui G., Sen L., Gambhir S.S. Preclinical safety evaluation of 18F-FHBG: a PET reporter probe for imaging herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk's expression. J. Nucl. Med. 2006, 47:706-715.
    • (2006) J. Nucl. Med. , vol.47 , pp. 706-715
    • Yaghoubi, S.S.1    Couto, M.A.2    Chen, C.C.3    Polavaram, L.4    Cui, G.5    Sen, L.6    Gambhir, S.S.7
  • 96
    • 44149101969 scopus 로고    scopus 로고
    • A new acycloguanosine-specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs
    • Likar Y., Dobrenkov K., Olszewska M., Vider E., Shenker L., Cai S., Pillarsetty N., Hricak H., Ponomarev V. A new acycloguanosine-specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs. J. Nucl. Med. 2008, 49:713-720.
    • (2008) J. Nucl. Med. , vol.49 , pp. 713-720
    • Likar, Y.1    Dobrenkov, K.2    Olszewska, M.3    Vider, E.4    Shenker, L.5    Cai, S.6    Pillarsetty, N.7    Hricak, H.8    Ponomarev, V.9
  • 99
    • 33845532052 scopus 로고    scopus 로고
    • Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival
    • Kim S.J., Doudet D.J., Studenov A.R., Nian C., Ruth T.J., Gambhir S.S., McIntosh C.H. Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival. Nat. Med. 2006, 12:1423-1428.
    • (2006) Nat. Med. , vol.12 , pp. 1423-1428
    • Kim, S.J.1    Doudet, D.J.2    Studenov, A.R.3    Nian, C.4    Ruth, T.J.5    Gambhir, S.S.6    McIntosh, C.H.7
  • 101
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide 1
    • Holst J.J. The physiology of glucagon-like peptide 1. Physiol. Rev. 2007, 87:1409-1439.
    • (2007) Physiol. Rev. , vol.87 , pp. 1409-1439
    • Holst, J.J.1
  • 102
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • Baggio L.L., Drucker D.J. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007, 132:2131-2157.
    • (2007) Gastroenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 103
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells
    • Goke R., Fehmann H.C., Linn T., Schmidt H., Krause M., Eng J., Goke B. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. J. Biol. Chem. 1993, 268:19650-19655.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19650-19655
    • Goke, R.1    Fehmann, H.C.2    Linn, T.3    Schmidt, H.4    Krause, M.5    Eng, J.6    Goke, B.7
  • 104
    • 0026648961 scopus 로고
    • Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
    • Eng J., Kleinman W.A., Singh L., Singh G., Raufman J.P. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J. Biol. Chem. 1992, 267:7402-7405.
    • (1992) J. Biol. Chem. , vol.267 , pp. 7402-7405
    • Eng, J.1    Kleinman, W.A.2    Singh, L.3    Singh, G.4    Raufman, J.P.5
  • 108
    • 78649330145 scopus 로고    scopus 로고
    • Synthesis and evaluation of F-18-exendin as a potential biomarker to measure pancreatic beta-cell mass
    • Wang Y., Lim K., Normandin M., Zhao X., Cline G., Ding Y.-S. Synthesis and evaluation of F-18-exendin as a potential biomarker to measure pancreatic beta-cell mass. J. Nucl. Med. Meet. Abstr. 2010, 51:195.
    • (2010) J. Nucl. Med. Meet. Abstr. , vol.51 , pp. 195
    • Wang, Y.1    Lim, K.2    Normandin, M.3    Zhao, X.4    Cline, G.5    Ding, Y.-S.6
  • 110
    • 0036414286 scopus 로고    scopus 로고
    • Specific monoclonal antibodies against the surface of rat islet beta cells
    • Konidaris C., Simonson W., Michelsen B., Papadopoulos G.K. Specific monoclonal antibodies against the surface of rat islet beta cells. Cell Biol. Int. 2002, 26:817-828.
    • (2002) Cell Biol. Int. , vol.26 , pp. 817-828
    • Konidaris, C.1    Simonson, W.2    Michelsen, B.3    Papadopoulos, G.K.4
  • 111
    • 0026689571 scopus 로고
    • Monoclonal antibody-mediated cytotoxicity against rat beta cells detected in vitro does not cause beta-cell destruction in vivo
    • Ziegler B., Lucke S., Kohler E., Hehmke B., Schlosser M., Witt S., Besch W., Ziegler M. Monoclonal antibody-mediated cytotoxicity against rat beta cells detected in vitro does not cause beta-cell destruction in vivo. Diabetologia 1992, 35:608-613.
    • (1992) Diabetologia , vol.35 , pp. 608-613
    • Ziegler, B.1    Lucke, S.2    Kohler, E.3    Hehmke, B.4    Schlosser, M.5    Witt, S.6    Besch, W.7    Ziegler, M.8
  • 112
    • 0023892258 scopus 로고
    • Antigen expression of the pancreatic beta-cells is dependent on their functional state, as shown by a specific, BB rat monoclonal autoantibody IC2
    • Buschard K., Brogren C.H., Ropke C., Rygaard J. Antigen expression of the pancreatic beta-cells is dependent on their functional state, as shown by a specific, BB rat monoclonal autoantibody IC2. APMIS 1988, 96:342-346.
    • (1988) APMIS , vol.96 , pp. 342-346
    • Buschard, K.1    Brogren, C.H.2    Ropke, C.3    Rygaard, J.4
  • 113
    • 0343832903 scopus 로고    scopus 로고
    • 125I-labelled mouse monoclonal antibody directed against pancreatic B-cell surface ganglioside(s) in control and diabetic rats
    • 125I-labelled mouse monoclonal antibody directed against pancreatic B-cell surface ganglioside(s) in control and diabetic rats. Cell Biochem. Funct. 2001, 19:107-115.
    • (2001) Cell Biochem. Funct. , vol.19 , pp. 107-115
    • Ladriere, L.1    Malaisse-Lagae, F.2    Alejandro, R.3    Malaisse, W.J.4
  • 114
    • 0035487329 scopus 로고    scopus 로고
    • Noninvasive in vivo measurement of beta-cell mass in mouse model of diabetes
    • Moore A., Bonner-Weir S., Weissleder R. Noninvasive in vivo measurement of beta-cell mass in mouse model of diabetes. Diabetes 2001, 50:2231-2236.
    • (2001) Diabetes , vol.50 , pp. 2231-2236
    • Moore, A.1    Bonner-Weir, S.2    Weissleder, R.3
  • 115
    • 23044438069 scopus 로고    scopus 로고
    • Quantitative evaluation of a monoclonal antibody and its fragment as potential markers for pancreatic beta cell mass
    • Hampe C.S., Wallen A.R., Schlosser M., Ziegler M., Sweet I.R. Quantitative evaluation of a monoclonal antibody and its fragment as potential markers for pancreatic beta cell mass. Exp. Clin. Endocrinol. Diab. 2005, 113:381-387.
    • (2005) Exp. Clin. Endocrinol. Diab. , vol.113 , pp. 381-387
    • Hampe, C.S.1    Wallen, A.R.2    Schlosser, M.3    Ziegler, M.4    Sweet, I.R.5
  • 119
    • 33646519900 scopus 로고    scopus 로고
    • Synthesis and evaluation of radioiodinated substituted beta-naphthylalanine as a potential probe for pancreatic beta-cells imaging
    • Amartey J.K., Esguerra C., Al-Jammaz I., Parhar R.S., Al-Otaibi B. Synthesis and evaluation of radioiodinated substituted beta-naphthylalanine as a potential probe for pancreatic beta-cells imaging. Appl. Radiat. Isot. 2006, 64:769-777.
    • (2006) Appl. Radiat. Isot. , vol.64 , pp. 769-777
    • Amartey, J.K.1    Esguerra, C.2    Al-Jammaz, I.3    Parhar, R.S.4    Al-Otaibi, B.5
  • 120
    • 0029880651 scopus 로고    scopus 로고
    • Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries
    • Barry M.A., Dower W.J., Johnston S.A. Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries. Nat. Med. 1996, 2:299-305.
    • (1996) Nat. Med. , vol.2 , pp. 299-305
    • Barry, M.A.1    Dower, W.J.2    Johnston, S.A.3


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