Consequences of host heterogeneity, epitope immunodominance, and immune breadth for strain competition

Journal of Theoretical Biology

Volumn 270, Issue 1, 2011, Pages 80-87

  Cobey, Sarah ^a   Pascual, Mercedes ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Cross immunity; Host heterogeneity; Immunodominance; Influenza; Status based model

Indexed keywords

EPITOPE;

HETEROGENEITY; HOST; IMMUNE RESPONSE; IMMUNITY; INFLUENZA; PATHOGEN;

ARTICLE; BINDING COMPETITION; CONTROLLED STUDY; GENOTYPE PHENOTYPE CORRELATION; HOST PATHOGEN INTERACTION; IMMUNE RESPONSE; IMMUNOGENICITY; INFLUENZA VIRUS; INTERSPECIFIC COMPETITION; PRIORITY JOURNAL; STRAIN DIFFERENCE; VIRUS STRAIN;

ADAPTIVE IMMUNITY; ALGORITHMS; COMPUTER SIMULATION; CROSS REACTIONS; GENETIC HETEROGENEITY; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNODOMINANT EPITOPES; INFECTION; INFLUENZA, HUMAN; MODELS, IMMUNOLOGICAL; ORTHOMYXOVIRIDAE; STOCHASTIC PROCESSES;

EID: 78649323755     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2010.11.009     Document Type: Article

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