Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis

European Journal of Clinical Pharmacology

Volumn 66, Issue 11, 2010, Pages 1119-1130

  Joy, Melanie S ^a,b   Boyette, Tammy ^a   Hu, Yichun ^a   Wang, Jinzhao ^a   La, Mary ^a   Hogan, Susan L ^a   Stewart, Paul W ^c   Falk, Ronald J ^a   Dooley, Mary Anne ^a   Smith, Philip C ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b University of North Carolina   (United States)

^c IL   (United States)

Author keywords

ABCB1; Glomerulonephritis; MDR1; Mycophenolic acid; UGT1A7; UGT2B7

Indexed keywords

CREATININE; GLUCURONOSYLTRANSFERASE 1A7; GLUCURONOSYLTRANSFERASE 2B7; MULTIDRUG RESISTANCE PROTEIN 1; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CAUCASIAN; CLINICAL ARTICLE; CREATININE BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; FEMALE; GLOMERULONEPHRITIS; HETEROZYGOSITY; HUMAN; MALE; MAXIMUM PLASMA CONCENTRATION; PHARMACOGENOMICS; PRIORITY JOURNAL; TIME TO MAXIMUM PLASMA CONCENTRATION; URINARY EXCRETION; WEIGHT GAIN;

ADULT; AGED; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; BIOLOGICAL MARKERS; CREATININE; ENZYME INHIBITORS; FEMALE; GENOTYPE; GLUCURONOSYLTRANSFERASE; HUMANS; LINEAR MODELS; LUPUS NEPHRITIS; MALE; MIDDLE AGED; MYCOPHENOLIC ACID; P-GLYCOPROTEIN; POLYMORPHISM, GENETIC; VASCULITIS;

EID: 78649315731     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-010-0846-x     Document Type: Article

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