Introduction to the Discipline of Toxicology

Toxicology and Risk Assessment: A Comprehensive Introduction

Volumn , Issue , 2008, Pages 1-18

  Greim, Helmut ^a   Snyder, Robert ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Dose response relationship; Enterohepatic circulation; Gap junction mediated intercellular communication; No observable effect level (NOEL); Occupational exposure standards; Oral cavity and gastrointestinal tract; Persistent accumulated damage; Phototoxicity and photoallergic reactions; Single occluded patch; Tumor suppressor genes and apoptosis

Indexed keywords

EID: 78649313802     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470868959.ch1     Document Type: Chapter

References (6)

1. Greim, H. and Deml, E. (1996), Toxikologie, Eine Einführung für Naturwissenschaftler und Mediziner, VCH Verlagsgemeinschaft mbH, Weinheim.
2. ParaceIsus, Selected Writings, ed. J. Jacobi, transl. N. Guterman (1951), p. 95, Princeton University Press, Princeton, NJ.
3. EFSA (European Safety Authority): Opinion of the Scientific Committee on a request from EFSA related to A Harmonized Approach for Risk Assessment of Substances Which are both Genotoxic and Carcinogenic. http://www.efsa.europa.eu/en/science/sc_commitee/sc_opinions/1201.html
4. IARC (International Agency for the Research of Cancer): Monographs on the evaluation of carcinogenic risks to humans, Geneva.
5. Kroes, R., Kleiner J., and Renwick A. (2005): The Threshold of Toxicological Concern Concept in Risk Assessment, Toxicol. Sci., 86, 226-230. http://ecb.jrc.it/tgddoc/ Technical Guidance Document, European Chemicals Bureau.
6. US EPA Assessing Health Risks from Pesticides (Pesticides: Topical and Chemical Fact Sheets). http://www.epa.gov/pesticides/factsheets/riskassess.htm