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Volumn 3-4, Issue , 2007, Pages 11-32

Processing of Protein-Bound N-Glycans

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EID: 78649294518     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-044451967-2/00034-9     Document Type: Chapter
Times cited : (5)

References (320)
  • 3
    • 77956799079 scopus 로고
    • Biosynthesis. The coenzymic role of phosphodolichols
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Hemming F.W. Biosynthesis. The coenzymic role of phosphodolichols. Glycoproteins 1995, Vol. 29a:127-143. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 127-143
    • Hemming, F.W.1
  • 4
    • 77956792354 scopus 로고
    • 2-protein: transfer 'en bloc' and processing
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • 2-protein: transfer 'en bloc' and processing. Glycoproteins 1995, Vol. 29a:145-152. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 145-152
    • Verbert, A.1
  • 14
    • 77956836494 scopus 로고
    • Biosynthesis. Glycosyltransferases involved in the synthesis of N-glycan antennae
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Schachter H. Biosynthesis. Glycosyltransferases involved in the synthesis of N-glycan antennae. Glycoproteins 1995, Vol. 29a:153-199. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 153-199
    • Schachter, H.1
  • 19
    • 77956869833 scopus 로고
    • Biosynthesis. Introduction
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Schachter H. Biosynthesis. Introduction. Glycoproteins 1995, Vol. 29a:123-126. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 123-126
    • Schachter, H.1
  • 20
    • 0342943737 scopus 로고
    • Biosynthesis. Substrate level controls for N-glycan assembly
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Schachter H. Biosynthesis. Substrate level controls for N-glycan assembly. Glycoproteins 1995, Vol. 29a:281-286. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 281-286
    • Schachter, H.1
  • 21
    • 77956800567 scopus 로고
    • Biosynthesis. Gene regulation of terminal glycosylation
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Glick M.C. Biosynthesis. Gene regulation of terminal glycosylation. Glycoproteins 1995, Vol. 29a:261-280. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 261-280
    • Glick, M.C.1
  • 22
    • 77956795185 scopus 로고
    • Biosynthesis. Compartmentation of glycoprotein biosynthesis
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Roth J. Biosynthesis. Compartmentation of glycoprotein biosynthesis. Glycoproteins 1995, Vol. 29a:287-312. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 287-312
    • Roth, J.1
  • 23
    • 77956817302 scopus 로고
    • Biosynthesis. Molecular basis of antigenic specificity in the ABO, H and Lewis blood group systems
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Watkins W.M. Biosynthesis. Molecular basis of antigenic specificity in the ABO, H and Lewis blood group systems. Glycoproteins 1995, Vol. 29a:313-390. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 313-390
    • Watkins, W.M.1
  • 24
    • 77956822858 scopus 로고
    • Biosynthesis. The role of polypeptide in the biosynthesis of protein-linked oligosaccharides
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Camphausen R.T., Yu H.-A., Cumming D.A. Biosynthesis. The role of polypeptide in the biosynthesis of protein-linked oligosaccharides. Glycoproteins 1995, Vol. 29a:391-414. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 391-414
    • Camphausen, R.T.1    Yu, H.-A.2    Cumming, D.A.3
  • 25
    • 77956853120 scopus 로고
    • Biosynthesis. How can N-linked glycosylation and processing inhibitors be used to study carbohydrate synthesis and function
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Pan Y.T., Elbein A.D. Biosynthesis. How can N-linked glycosylation and processing inhibitors be used to study carbohydrate synthesis and function. Glycoproteins 1995, Vol. 29a:415-454. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 415-454
    • Pan, Y.T.1    Elbein, A.D.2
  • 71
    • 0018714570 scopus 로고
    • Surani M.A.H. Cell 1979, 18:217-227.
    • (1979) Cell , vol.18 , pp. 217-227
    • Surani, M.A.H.1
  • 74
    • 33751207949 scopus 로고    scopus 로고
    • Dolichol phosphate GlcNAc-1-P transferase
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Hübel A., Schwarz R.T. Dolichol phosphate GlcNAc-1-P transferase. Handbook of Glycosyltransferases and Related Genes 2002, 550-556. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 550-556
    • Hübel, A.1    Schwarz, R.T.2
  • 89
    • 0342958392 scopus 로고
    • Primary structure of glycoprotein glycans
    • Elsevier, Amsterdam, The Netherlands, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Vliegenthart J.F.G., Montreuil J. Primary structure of glycoprotein glycans. Glycoproteins 1995, Vol. 29a:13-28. Elsevier, Amsterdam, The Netherlands. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 13-28
    • Vliegenthart, J.F.G.1    Montreuil, J.2
  • 90
    • 0002607662 scopus 로고
    • Synthesis of asparagine-linked oligosaccharides: pathways, genetics and metabolic regulation
    • Marcel, New York, H.J. Allen, E.C. Kisailus (Eds.)
    • Cummings R.D. Synthesis of asparagine-linked oligosaccharides: pathways, genetics and metabolic regulation. Glycoconjugates, Composition, Structure and Function 1992, 333-360. Marcel, New York. H.J. Allen, E.C. Kisailus (Eds.).
    • (1992) Glycoconjugates, Composition, Structure and Function , pp. 333-360
    • Cummings, R.D.1
  • 93
    • 84882491607 scopus 로고    scopus 로고
    • N-acetylglucosaminyltransferase-I
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Stanley P. N-acetylglucosaminyltransferase-I. Handbook of Glycosyltransferases and Related Genes 2002, 61-69. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 61-69
    • Stanley, P.1
  • 95
    • 77956828608 scopus 로고
    • Protein glycosylation in yeast
    • Elsevier, Amsterdam, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Lehle L., Tanner W. Protein glycosylation in yeast. Glycoproteins 1995, Vol. 29a:475-509. Elsevier, Amsterdam. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 475-509
    • Lehle, L.1    Tanner, W.2
  • 96
    • 77956818765 scopus 로고
    • Bacterial glycoproteins
    • Elsevier, Amsterdam, J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.)
    • Sumper M., Wieland F.T. Bacterial glycoproteins. Glycoproteins 1995, Vol. 29a:455-473. Elsevier, Amsterdam. J. Montreuil, J.F.G. Vliegenthart, H. Schachter (Eds.).
    • (1995) Glycoproteins , vol.29 A , pp. 455-473
    • Sumper, M.1    Wieland, F.T.2
  • 117
    • 0011443439 scopus 로고    scopus 로고
    • α-Mannosidase-II
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Moremen K.W. α-Mannosidase-II. Handbook of Glycosyltransferases and Related Genes 2002, 600-606. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 600-606
    • Moremen, K.W.1
  • 150
    • 7244259588 scopus 로고    scopus 로고
    • N-acetylglucosaminyltransferase-II
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Schachter H. N-acetylglucosaminyltransferase-II. Handbook of Glycosyltransferases and Related Genes 2002, 70-79. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 70-79
    • Schachter, H.1
  • 164
    • 84919544965 scopus 로고    scopus 로고
    • N-acetylglucosaminyltransferase-III
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Ikeda Y., Taniguchi N. N-acetylglucosaminyltransferase-III. Handbook of Glycosyltransferases and Related Genes 2002, 80-86. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 80-86
    • Ikeda, Y.1    Taniguchi, N.2
  • 169
    • 0011795397 scopus 로고
    • The three-dimensional structure of N-linked oligosaccharides
    • Wiley, New York, V. Ginsburg, P.W. Robbins (Eds.)
    • Carver J.P., Brisson J.-R. The three-dimensional structure of N-linked oligosaccharides. Biology of Carbohydrates 1984, Vol. 2:289-331. Wiley, New York. V. Ginsburg, P.W. Robbins (Eds.).
    • (1984) Biology of Carbohydrates , vol.2 , pp. 289-331
    • Carver, J.P.1    Brisson, J.-R.2
  • 242
    • 77955267364 scopus 로고    scopus 로고
    • N-acetylglucosaminyltransferase-V
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Dennis J.W. N-acetylglucosaminyltransferase-V. Handbook of Glycosyltransferases and Related Genes 2002, 94-101. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 94-101
    • Dennis, J.W.1
  • 266
    • 83455237775 scopus 로고    scopus 로고
    • N-acetylglucosaminyltransferase-VI
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Honke K., Taniguchi N. N-acetylglucosaminyltransferase-VI. Handbook of Glycosyltransferases and Related Genes 2002, 102-106. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 102-106
    • Honke, K.1    Taniguchi, N.2
  • 273
    • 36849054910 scopus 로고    scopus 로고
    • β4-Galactosyltransferase-I
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Shaper N.L., Shaper J.H. β4-Galactosyltransferase-I. Handbook of Glycosyltransferases and Related Genes 2002, 11-19. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 11-19
    • Shaper, N.L.1    Shaper, J.H.2
  • 274
    • 0013526360 scopus 로고    scopus 로고
    • β4-Galactosyltransferase-II,-III,-IV,-V,-VI, and -VII
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Furukawa K., Clausen H. β4-Galactosyltransferase-II,-III,-IV,-V,-VI, and -VII. Handbook of Glycosyltransferases and Related Genes 2002, 20-26. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 20-26
    • Furukawa, K.1    Clausen, H.2
  • 275
    • 85042751165 scopus 로고    scopus 로고
    • β3-Galactosyltransferase-IV
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Furukawa K. β3-Galactosyltransferase-IV. Handbook of Glycosyltransferases and Related Genes 2002, 33-36. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 33-36
    • Furukawa, K.1
  • 276
    • 70249102643 scopus 로고    scopus 로고
    • β3-Galactosyltransferase-I, -II, and -III
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Hennet T., Berger E.G. β3-Galactosyltransferase-I, -II, and -III. Handbook of Glycosyltransferases and Related Genes 2002, 27-32. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 27-32
    • Hennet, T.1    Berger, E.G.2
  • 277
    • 85042757693 scopus 로고    scopus 로고
    • β3-Galactosyltransferase-V
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Narimatsu H. β3-Galactosyltransferase-V. Handbook of Glycosyltransferases and Related Genes 2002, 37-43. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 37-43
    • Narimatsu, H.1
  • 288
    • 1642315127 scopus 로고    scopus 로고
    • β3-N-acetylglucosaminyltransferase (iGnT)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Fukuda M. β3-N-acetylglucosaminyltransferase (iGnT). Handbook of Glycosyltransferases and Related Genes 2002, 114-124. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 114-124
    • Fukuda, M.1
  • 290
    • 33745978223 scopus 로고    scopus 로고
    • ST3Gal-II (SAT-IV)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Hamamoto T., Tsuji S. ST3Gal-II (SAT-IV). Handbook of Glycosyltransferases and Related Genes 2002, 274-278. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 274-278
    • Hamamoto, T.1    Tsuji, S.2
  • 294
    • 4244072469 scopus 로고    scopus 로고
    • α2-Fucosyltransferases (FUT1, FUT2, and Sec1)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Oriol R., Mollicone R. α2-Fucosyltransferases (FUT1, FUT2, and Sec1). Handbook of Glycosyltransferases and Related Genes 2002, 205-217. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 205-217
    • Oriol, R.1    Mollicone, R.2
  • 295
    • 0038135638 scopus 로고    scopus 로고
    • α3/4-Fucosyltransferase (FUT3, Lewis enzyme)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Narimatsu H. α3/4-Fucosyltransferase (FUT3, Lewis enzyme). Handbook of Glycosyltransferases and Related Genes 2002, 218-225. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 218-225
    • Narimatsu, H.1
  • 296
    • 1642402829 scopus 로고    scopus 로고
    • α3-Fucosyltransferase-IV (FUT4)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Narimatsu H. α3-Fucosyltransferase-IV (FUT4). Handbook of Glycosyltransferases and Related Genes 2002, 226-231. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 226-231
    • Narimatsu, H.1
  • 297
    • 84919544964 scopus 로고    scopus 로고
    • α3-Fucosyltransferase-VII (FUT7)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Narimatsu H. α3-Fucosyltransferase-VII (FUT7). Handbook of Glycosyltransferases and Related Genes 2002, 246-251. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 246-251
    • Narimatsu, H.1
  • 298
    • 26444509271 scopus 로고    scopus 로고
    • α3-Fucosyltransferase-IX (FUT9)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Narimatsu H. α3-Fucosyltransferase-IX (FUT9). Handbook of Glycosyltransferases and Related Genes 2002, 252-258. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 252-258
    • Narimatsu, H.1
  • 299
    • 83455178610 scopus 로고    scopus 로고
    • α3-Fucosyltransferase-V (FUT5)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Kannagi R. α3-Fucosyltransferase-V (FUT5). Handbook of Glycosyltransferases and Related Genes 2002, 232-236. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 232-236
    • Kannagi, R.1
  • 300
    • 70249098332 scopus 로고    scopus 로고
    • α3-Fucosyltransferase-VI (FUT6)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Kannagi R. α3-Fucosyltransferase-VI (FUT6). Handbook of Glycosyltransferases and Related Genes 2002, 237-245. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 237-245
    • Kannagi, R.1
  • 301
    • 31144460800 scopus 로고    scopus 로고
    • α6-Fucosyltransferase-VIII (FUT8)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Miyoshi E., Taniguchi N. α6-Fucosyltransferase-VIII (FUT8). Handbook of Glycosyltransferases and Related Genes 2002, 259-263. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 259-263
    • Miyoshi, E.1    Taniguchi, N.2
  • 307
    • 1642315127 scopus 로고    scopus 로고
    • β6-N-acetylglucosaminyltransferase (IGnT)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Fukuda M. β6-N-acetylglucosaminyltransferase (IGnT). Handbook of Glycosyltransferases and Related Genes 2002, 125-132. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 125-132
    • Fukuda, M.1
  • 315
    • 33746016094 scopus 로고    scopus 로고
    • ST3Gal-V (GM3 synthase, SAT-1)
    • Springer, Tokyo, Japan, N. Taniguchi, K. Honke, M. Fukuda (Eds.)
    • Saito M., Ishii A. ST3Gal-V (GM3 synthase, SAT-1). Handbook of Glycosyltransferases and Related Genes 2002, 289-294. Springer, Tokyo, Japan. N. Taniguchi, K. Honke, M. Fukuda (Eds.).
    • (2002) Handbook of Glycosyltransferases and Related Genes , pp. 289-294
    • Saito, M.1    Ishii, A.2


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