The use of dynamic mechanical analysis (DMA) to evaluate plasticization of acrylic polymer films under simulated gastrointestinal conditions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 76, Issue 3, 2010, Pages 493-497

  Fadda, H M ^a   Khanna, M ^a   Santos, J C ^a   Osman, D ^a   Gaisford, S ^a   Basit, A W ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Antiplasticizer; Enteric coatings; Film coating; In vitro in vivo correlations; Loss modulus; Molecular mobility

Indexed keywords

ACETYLTRIETHYLCITRATE; EUDRAGIT; MACROGOL; PHTHALIC ACID DIBUTYL ESTER; PLASTICIZER; PROPYLENE GLYCOL; SEBACIC ACID DIBUTYL ESTER; TRIACETIN; TRIETHYLCITRATE; UNCLASSIFIED DRUG;

ARTICLE; BODY TEMPERATURE; DRUG RELEASE; DYNAMIC MECHANICAL ANALYSIS; FILM COATING; PH MEASUREMENT; SIMULATION; STOMACH; THERMAL ANALYSIS;

CITRATES; COMPUTER SIMULATION; DIFFUSION; DRUG DELIVERY SYSTEMS; HYDROGEN-ION CONCENTRATION; MOLECULAR CONFORMATION; PLASTICIZERS; POLYETHYLENE GLYCOLS; POLYMERS; POLYMETHACRYLIC ACIDS; STOMACH; TRANSITION TEMPERATURE;

EID: 78549294472     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.08.007     Document Type: Article

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