Combinatorial library discovery of small molecule inhibitors of lung cancer proliferation and parathyroid hormone-related protein expression

Cancer Biology and Therapy

Volumn 10, Issue 10, 2010, Pages 1067-1075

  Hastings, Randolph H ^a,b,d   Burton, Douglas W ^a   Nefzi, Adel ^e   Montgrain, Philippe R ^a,c   Quintana, Rick ^a   Deftos, Leonard J ^a,c,d  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b University of California   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

Gene expression regulation; Intercellular signaling peptides; Non small cell lung carcinoma; Paraneoplastic endocrine syndromes; Small molecule libraries

Indexed keywords

GUANIDINE; HETEROCYCLIC AMINE; LUCIFERASE; MESSENGER RNA; PARATHYROID HORMONE RELATED PROTEIN; THIOUREA; CYCLOPEPTIDE;

ARTICLE; CARCINOMA CELL; CELL GROWTH; CELL PROLIFERATION; COMBINATORIAL LIBRARY; HUMAN; HUMAN CELL; LUNG CARCINOMA; PROTEIN EXPRESSION; ADENOCARCINOMA; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; LUNG TUMOR; METABOLISM; PATHOLOGY; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TUMOR CELL CULTURE; WESTERN BLOTTING;

ADENOCARCINOMA; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; LUCIFERASES; LUNG NEOPLASMS; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDES, CYCLIC; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 78549293136     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.10.10.13374     Document Type: Article

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