Bone marrow lesions in people with knee osteoarthritis predict progression of disease and joint replacement: A longitudinal study

Rheumatology

Volumn 49, Issue 12, 2010, Pages 2413-2419

  Tanamas, Stephanie K ^a   Wluka, Anita E ^a   Pelletier, Jean Pierre ^b   Pelletier, Johanne M ^b   Abram, François ^c   Berry, Patricia A ^a   Wang, Yuanyuan ^a   Jones, Graeme ^d   Cicuttini, Flavia M ^a  

^a MONASH UNIVERSITY   (Australia)

^b NOTRE DAME HOSPITAL   (Canada)

^c INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^d UNIVERSITY OF TASMANIA   (Australia)

Author keywords

Bone marrow lesions; Cartilage loss; Knee joint replacement; Osteoarthritis; Tibial cartilage

Indexed keywords

ADULT; ARTICLE; BONE MARROW TUMOR; CARTILAGE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; FEMALE; HUMAN; KNEE ARTHROPLASTY; KNEE OSTEOARTHRITIS; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTOR VARIABLE; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT;

AGED; ARTHROPLASTY, REPLACEMENT, KNEE; BONE MARROW DISEASES; CARTILAGE, ARTICULAR; DISEASE PROGRESSION; FEMALE; HUMANS; KNEE; KNEE JOINT; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; RISK FACTORS; STATISTICS AS TOPIC;

EID: 78549283823     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keq286     Document Type: Article

References (26)

1. Felson DT, Chaisson CE, Hill CL et al. The association of bone marrow lesions with pain in knee osteoarthritis. Ann Inter Med 2001;134:514-49.
2. Wluka AE, Wang Y, Davies-Tuck M, English DR, Giles GG, Cicuttini FM. Bone marrow lesions predict progression of cartilage defects and loss of cartilage volume in healthy middle-aged adults without knee pain over 2 yrs. Rheumatology 2008;47:1392-6.
3. Zanetti M, Bruder E, Romero J, Hodler J. Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings. Radiology 2000;215: 835-40.
4. d'Anjou MA, Troncy E, Moreau M et al. Temporal assessment of bone marrow lesions on magnetic resonance imaging in a canine model of knee osteoarthritis: impact of sequence selection. Osteoarthritis Cartilage 2008;16:1307-11.
5. Martig S, Boisclair J, Konar M, Spreng D, Lang J. MRI characteristics and histology of bone marrow lesions in dogs with experimentally induced osteoarthritis. Vet Radiol Ultrasound 2007;48:105-12.
6. Bollet AJ. Edema of the bone marrow can cause pain in osteoarthritis and other diseases of bone and joints [comment]. Ann Intern Med 2001;134:591-3.
7. Felson DT, McLaughlin S, Goggins J et al. Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med 2003;139:330-6.
8. Hunter DJ, Zhang Y, Niu J et al. Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis. Arthritis Rheum 2006;54:1529-35.
9. Raynauld JP, Martel-Pelletier J, Berthiaume MJ et al. Correlation between bone lesion changes and cartilage volume loss in patients with osteoarthritis of the knee as assessed by quantitative magnetic resonance imaging over a 24-month period. Ann Rheum Dis 2008;67:683-8.
10. Roemer FW, Guermazi A, Javaid MK et al. Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss - the MOST study. A longitudinal multicenter study of knee osteoarthritis. Ann Rheum Dis 2009;68:1461-5.
11. Scher C, Craig J, Nelson F. Bone marrow edema in the knee in osteoarthrosis and association with total knee arthroplasty within a three-year follow-up. Skeletal Radiol 2008;37:609-17.
12. Bellamy N. Outcome measures in osteoarthritis clinical trials. J Rheumatol 1995;22(Suppl. 43):49-51.
13. Altman R, Asch E, Bloch D et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 1986;29: 1039-49.
14. Cicuttini F, Wluka A, Hankin J, Wang Y. Longitudinal study of the relationship between knee angle and tibiofemoral cartilage volume in subjects with knee osteoarthritis. Rheumatology 2004;43:321-4.
15. Cicuttini FM, Wluka AE, Forbes A, Wolfe R. Comparison of tibial cartilage volume and radiologic grade of the tibiofemoral joint. Arthritis Rheum 2003;48:682-8.
16. Wluka AE, Stuckey S, Snaddon J, Cicuttini FM. The determinants of change in tibial cartilage volume in osteoarthritic knees. Arthritis Rheum 2002;46:2065-72.
17. Garnero P, Peterfy C, Zaim S, Schoenharting M. Bone marrow abnormalities on magnetic resonance imaging are associated with type II collagen degradation in knee osteoarthritis: a three-month longitudinal study. Arthritis Rheum 2005;52:2822-9.
18. Bergman AG, Willen HK, Lindstrand AL, Pettersson HT. Osteoarthritis of the knee: correlation of subchondral MR signal abnormalities with histopathologic and radiographic features. Skeletal Radiol 1994;23:445-8.
19. Findlay DM. Vascular pathology and osteoarthritis. Rheumatology 2007;46:1763-8.
20. Winet H, Hsieh A, Bao JY. Approaches to study of ischemia in bone. J Biomed Mater Res 1998;43:410-21.
21. Schipplein OD, Andriacchi TP. Interaction between active and passive knee stabilizers during level walking. J Orthop Res 1991;9:113-9.
22. Reichenbach S, Sterchi R, Scherer M et al. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. Ann Intern Med 2007;146:580-90.
23. Black C, Clar C, Henderson R et al. The clinical effectiveness of glucosamine and chondroitin supplements in slowing or arresting progression of osteoarthritis of the knee: a systematic review and economic evaluation. Health Technol Assess 2009;13: 1-148.
24. Vlad SC, LaValley MP, McAlindon TE, Felson DT. Glucosamine for pain in osteoarthritis: why do trial results differ? Arthritis Rheum 2007;56:2267-77.
25. Peterfy CG, Gold G, Eckstein F, Cicuttini F, Dardzinski B, Stevens R. MRI protocols for whole-organ assessment of the knee in osteoarthritis. Osteoarthritis Cartilage 2006; 14(Suppl. A):A95-111.
26. Cicuttini FM, Jones G, Forbes A, Wluka AE. Rate of cartilage loss at two years predicts subsequent total knee arthroplasty: a prospective study. Ann Rheum Dis 2004;63:1124-7.