Interpretation of correlations in setpoint viral load in transmitting couples

AIDS

Volumn 24, Issue 16, 2010, Pages 2596-2597

  Fraser, Christophe ^a   Hollingsworth, T Déirdre ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYSIS OF VARIANCE; CORRELATION COEFFICIENT; GENOTYPE; LETTER; NONHUMAN; PRIORITY JOURNAL; VIRUS ACTIVATION; VIRUS CELL INTERACTION; VIRUS LOAD; VIRUS PATHOGENESIS; VIRUS TRANSMISSION;

FAMILY CHARACTERISTICS; FEMALE; GENETIC VARIATION; HIV INFECTIONS; HIV-1; HUMANS; MALE; PHYLOGENY; RNA, VIRAL; VIRAL LOAD;

EID: 78549275409     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32833e7a64     Document Type: Letter

References (6)

1. Hecht FM, Hartogensis W, Bragg L, Bacchetti P, Atchison R, Grant R, et al. HIV RNA level in early infection is predicted by viral load in the transmission source. AIDS 2010;24:941- 945.
2. van der Kuyl AC, Jurriaans S, Pollakis G, Bakker M, Cornelissen M. HIV RNA levels in transmission sources only weakly predict plasma viral load in recipients. AIDS 2010;24:1607-1608.
3. Tang J, Tang S, Lobashevsky E, Zulu I, Aldrovandi G, Allen S, Kaslow RA. HLA allele sharing and HIV type 1 viremia in seroconverting Zambians with known transmitting partners. AIDS Res Hum Retroviruses 2004;20:19-25.
4. Hollingsworth TD, Laeyendecker O, Shirreff G, Donnelly CA, Serwadda D, Wawer MJ, et al. HIV-1 transmitting couples have similar viral load set-points in Rakai, Uganda. PLoS Pathog 2010; 6:e1000876.
5. Fellay J, Ge D, Shianna KV, Colombo S, Ledergerber B, Cirulli ET, et al. Common genetic variation and the control of HIV-1 in humans. PLoS Genet 2009; 5:e1000791 .
6. Fraser C, Hollingsworth TD, Chapman R, deWolf F, HanageWP. Variation in HIV-1 set-pointviral load:Epidemiological analysis and an evolutionary hypothesis. Proc Natl Acad Sci USA 2007; 104:17441-17446.