The mechanical stress-activated serum-, glucocorticoid-regulated kinase 1 contributes to neointima formation in vein grafts

Circulation Research

Volumn 107, Issue 10, 2010, Pages 1265-1274

  Cheng, Jizhong ^a   Wang, Ying ^b   Ma, Yewei ^a   Chan, Bonita Tak Yee ^a   Yang, Min ^b   Liang, Anlin ^a   Zhang, Liping ^a   Li, Huihua ^b   Du, Jie ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

mammalian target of rapamycin complex; mechanical stretch; mTORC; neointima formation; serum , glucocorticoid regulated kinase 1

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; DACTINOMYCIN; KU 0063794; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAPAMYCIN; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SOMATOMEDIN C RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE PROGRESSION; CELL ISOLATION; CELL PROLIFERATION; ENZYME ACTIVATION; INTIMA; MECHANICAL STRESS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; TRANSCRIPTION INITIATION; VEIN GRAFT;

ANIMALS; CAROTID ARTERY INJURIES; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IMMEDIATE-EARLY PROTEINS; MALE; MAP KINASE KINASE 1; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; TIME FACTORS; TISSUE CULTURE TECHNIQUES; TRANS-ACTIVATORS; TRANSFECTION; TUNICA INTIMA; VEINS;

EID: 78549275373     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.110.222588     Document Type: Article

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