Noncompaction syndrome of the myocardium: Pathophysiology and imaging pearls

Journal of Thoracic Imaging

Volumn 25, Issue 4, 2010, Pages 326-332

  Zenooz, Navid A ^a   Zahka, Keneth G ^b   Siwik, Ernest S ^b   Gilkeson, Robert C ^c  

^a YALE NEW HAVEN HOSPITAL   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^c Case Western Reserve University   (United States)

Author keywords

computed tomography; magnetic resonance imaging; myocardium; noncompaction

Indexed keywords

ANTIARRHYTHMIC AGENT; ANTICOAGULANT AGENT;

ANTICOAGULANT THERAPY; ARTICLE; BARTH SYNDROME; CHROMOSOME XQ; COMPUTER ASSISTED TOMOGRAPHY; DEFIBRILLATOR; DIAGNOSTIC ACCURACY; DISEASE ASSOCIATION; EARLY DIAGNOSIS; ECHOCARDIOGRAPHY; EMBRYOLOGY; HEART ARRHYTHMIA; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE; HEART SCINTISCANNING; HEART TRANSPLANTATION; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; LINKAGE ANALYSIS; MYOCARDIAL DISEASE; NEUROLOGIC DISEASE; NONCOMPACTION SYNDROME OF THE MYOCARDIUM; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PROGNOSIS; SURVIVAL; THROMBOEMBOLISM; TRABECULAR BONE; X CHROMOSOME LINKAGE;

ECHOCARDIOGRAPHY; HEART; HUMANS; ISOLATED NONCOMPACTION OF THE VENTRICULAR MYOCARDIUM; MAGNETIC RESONANCE IMAGING; MYOCARDIUM; SYNDROME; TOMOGRAPHY, X-RAY COMPUTED;

EID: 78549264046     PISSN: 08835993     EISSN: None     Source Type: Journal    
DOI: 10.1097/RTI.0b013e31819ca93e     Document Type: Article

References (27)

1. Pignatelli RH, McMahon C, Dreyer WJ, et al. Clinical characterization of left ventricular noncompaction in children: a relatively common form of cardiomyopathy. Circulation. 2003;108:2672-2678.
2. Stollberger C, Finsterer J. Left ventricular hypertrabeculation/ noncompaction. J Am Soc Echocardiogr. 2004;17:91-100.
3. Chin TK, Perloff JK, Williams RG, et al. Isolated noncompac-tion of left ventricular myocardium: a study of eight cases. Circulation. 1990;82:507-513.
4. Towbin JA, Lipshultz SE. Genetics of neonatal cardiomyo-pathy. Curr Opin Cardiol. 1999;14:250-262.
5. Zambrano E, Marshalko SJ, Jaffe CC, et al. Isolated noncompaction of the ventricular myocardium: clinical and molecular aspects of a rare cardiomyopathy. Lab Invest. 2002; 82:117-122.
6. Rigopoulos A, Rizos IK, Aggeli C, et al. Isolated left ventricular noncompaction: an unclassified cardiomyopathy with severe prognosis in adults. Cardiology. 2002;98:25-32.
7. Ichida F, Hamamichi Y, Miyawaki T, et al. Clinical features of isolated noncompaction of the ventricular myocardium: long-term clinical course, hemodynamic properties, and genetic background. J Am Coll Cardiol. 1999;34:233-240.
8. Corrado G, Santarone M, Miglierina E, et al. Left ventricular hypertrabeculation/noncompaction with PMP22 duplication-based Charcot-Marie-Tooth disease type 1A. Ital Heart J. 2000;1:372-375.
9. Murphy RT, Thaman R, Blanes JG, et al. Natural history and familial characteristics of isolated left ventricular non-compaction. Eur Heart J. 2005;26:187-192.
10. Moreira FC, Miglioransa MH, Mautone MP, et al. Non-compaction of the left ventricle: a new cardiomyopathy is presented to the clinician. Sao Paulo Med J. 2006;124:31-35.
11. Oechslin EN, Attenhofer Jost CH, Rojas CR, et al. Long-term follow-up of 34 adults with isolated left ventricular noncom-paction: a distinct cardiomyopathy with poor prognosis. J Am Coll Cardiol. 2000;36:493-500.
12. Bleyl SB, Mumford BR, Brown-Harrison MC, et al. Xq28-linked noncompaction of the left ventricular myocardium: prenatal diagnosis and pathologic analysis of affected individuals. Am J Med Genet. 1997;72:257-265.
13. Bleyl SB, Mumford BR, Thompson V, et al. Neonatal, lethal noncompaction of the left ventricular myocardium is allelic with Barth syndrome. Am J Hum Genet. 1997;61:868-872.
14. Xing Y, Ichida F, Matsuoka T, et al. Genetic analysis in patients with left ventricular noncompaction and evidence for genetic heterogeneity. Mol Genet Metab. 2006;88: 71-77.
15. Valdes-Dapena M, Gilbert-Barness E. Cardiovascular causes for sudden infant death. Pediatr Pathol Mol Med. 2002;21: 195-211.
16. Finsterer J, Stollberger C, Blazek G, et al. Acquired noncompaction in Duchenne muscular dystrophy. Int J Cardiol. 2006;106:420-421.
17. McMahon CJ, Chang AC, Pignatelli RH, et al. Left ventricular noncompaction cardiomyopathy in association with trisomy 13. Pediatr Cardiol. 2005;26:477-479.
18. Finsterer J, Stollberger C, Kopsa W. Noncompaction on cardiac MRI in a patient with nail-patella syndrome and mithochondriopathy. Cardiology. 2003;100:48-49.
19. Finsterer J, Stollberger C, Blazek G. Neuromuscular implications in left ventricular hypertrabeculation/noncompaction. Int J Cardiol. 2006;110:288-300.
20. Ozkutlu S, Ayabakan C, Celiker A, et al. Noncompaction of ventricular myocardium: a study of twelve patients. J Am Soc Ecocardiogr. 2002;15:1523-1528.
21. Jenni R, Oechslin E, Schneider J, et al. Echocardiographic and patho-anatomical characteristics of isolated left ventricular non-compaction: a step towards a classification as a distinct cardiomyopathy. Heart. 2001;86:666-671.
22. Johnson MT, Zhang S, Gilkeson R, et al. Intrafamilial variability of noncompaction of the ventricular myocardium. Am Heart J. 2006;151:1012.e7-1012. e14.
23. Hamamichi Y, Ichida F, Hashimoto I, et al. Isolated noncompaction of the ventricular myocardium: ultrafast computed tomography and magnetic resonance imaging. Int J Cardiovasc Imaging. 2001;17:305-314.
24. Jenni R, Wyss CA, Oechslin EN, et al. Isolated ventricular noncompaction is associated with coronary microcirculatory dysfunction. J Am Coll Cardiol. 2002;39:450-454.
25. Elias J, Valadao W, Kuniyoshi R, et al. Isolated non-compaction of the myocardium. Arq Bras Cardiol. 2000;7: 95-97.
26. Neudorf UE, Hussein A, Trowitzsch E, et al. Clinical features of isolated noncompaction of the myocardium in children. Cardiol Young. 2001;11:439-442.
27. Lofiego C, Biagini E, Pasquale F, et al. Wide spectrum of presentation and variable outcomes of isolated left ventricular non-compaction. Heart. 2007;93:65-71.