Castanolide and epi-castanolide, two novel diterpenoids with a unique seco-norabietane skeleton from Salvia castanea Diels f. pubescens Stib

Tetrahedron Letters

Volumn 51, Issue 38, 2010, Pages 5083-5085

  Pan, Zheng Hong ^a,b,c   He, J ^a   Li, Yan ^a   Zhao, Yu ^a   Wua, Xing De ^a   Wang, Kou ^a   Peng, Li Yan ^a   Xu, Gang ^a   Zhao, Qin Shi ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b GUANGXI INSTITUTE OF BOTANY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Castanolide; Diterpenoid; Epi Castanolide; Salvia castanea Diels f. pubescens Stib.

Indexed keywords

CASTANOLIDE; DITERPENOID; EPI CASTANOLIDE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; DRUG ISOLATION; DRUG STRUCTURE; HETERONUCLEAR MULTIPLE BOND CORRELATION; MEDICINAL PLANT; PROTON NUCLEAR MAGNETIC RESONANCE; SALVIA; SALVIA CASTANEA; STEREOCHEMISTRY; X RAY DIFFRACTION;

CASTANEA; SALVIA;

EID: 78549246151     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.07.107     Document Type: Article

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17. 4, M = 316.38; orthorhombic, space group P212121; a = 6.5492 (12) Å, b = 11.936 (2) Å, c = 21.835 (4) Å, a = 90.00, b = 90.00, c = 90.00, V = 1706.9 (5) Å3, Z = 4, d = 1.231 g/cm3, crystal dimensions 0.21 × 0.14 × 0.08 mm were used for measurement on a SHELXL-97 with a graphite monochromater, Mo Ka radiation. The total number of reflections measured was 11131, of which 4058, were observed, I >2r(I). Final indices: R1 = 0.0584, wR2 = 0.0777. The crystal structure of 1 was solved by direct method SHLXS-97 (Sheldrick, 1990) and expanded using difference Fourier technique, refined by the program SHLXL-97 (Sheldrick, 1997) and the fullmatrix least-squares calculations. Crystallographic data for the structure of 1 have been deposited in the Cambridge Crystallographic Data Center (deposition number: CCDC 746691). Copies of these data can be obtained free of charge via www.ccdc.cam.ac.uk/conts/ retrieving.html (or from the Cambridge Crystallographic Data Center, 12, Union Road, Cambridge CB21EZ, UK; fax: +44 1223 336 033; or desposit@ccdc.cam.ac.uk).
18. 4Na, 339.1572).
19. 4, M = 316.38; monoclinic, space group P21; a = 8.4020 (14) Å, b = 11.1434 (18) Å, c = 9.4696 (15) Å, a = 90.00, b = 110.341 (2), c = 90.00, V = 831.3 (2) Å3, Z = 2, d = 1.264 g/cm3, crystal dimensions 0.23 × 0.18 × 0.12 mm were used for measurement on a SHELXL-97 with a graphite monochromater, Mo Ka radiation. The total number of reflections measured was 5381, of which 3394, were observed, I >2r(I). Final indices: R1 = 0.0448, wR2 = 0.0940. The crystal structure of 2 was solved by direct method SHLXS-97 (Sheldrick, 1990) and expanded using difference Fourier technique, refined by the program SHLXL-97 (Sheldrick, 1997) and the full-matrix least-squares calculations. Crystallographic data for the structure of 2 have been deposited in the Cambridge Crystallographic Data Center (deposition number: CCDC 746692). Copies of these data can be obtained free of charge via www.ccdc.cam.ac.uk/conts/retrieving.html (or from the Cambridge Crystallographic Data Center, 12, Union Road, Cambridge CB21EZ, UK; fax: +44 1223 336 033; or desposit@ccdc.cam.ac.uk). 11. Haro, G.; Kakisawa, H. Chem. Lett. 1990, 9, 1599.