Common oral manifestations of systemic disease

Otolaryngologic Clinics of North America

Volumn 44, Issue 1, 2011, Pages 161-182

  Islam, Nadim M ^a   Bhattacharyya, Indraneel ^b   Cohen, Donald M ^b  

^a INDIANA UNIVERSITY SCHOOL OF DENTISTRY   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF DENTISTRY   (United States)

Author keywords

Amyloidosis; Anemia; Crohn disease; Endocrine disease; Neoplasm; Oral manifestations; Pyostomatitis vegetans; Rheumatoid arthritis

Indexed keywords

ADDISON DISEASE; AMYLOIDOSIS; AUTOIMMUNE DISEASE; CONGENITAL HYPOTHYROIDISM; CROHN DISEASE; CUSHING SYNDROME; DIABETES MELLITUS; ENDOCRINE DISEASE; FAMILIAL HYPOPHOSPHATEMIC RICKETS; GASTROINTESTINAL DISEASE; GRAVES DISEASE; HEMATOLOGIC DISEASE; HISTIOCYTOSIS X; HUMAN; HYPERCORTISOLISM; HYPERTHYROIDISM; HYPOPARATHYROIDISM; HYPOPHOSPHATASIA; HYPOPHOSPHATEMIC RICKETS; HYPOTHYROIDISM; IRON DEFICIENCY ANEMIA; LEUKEMIA; METABOLIC DISORDER; METASTASIS; MOUTH DISEASE; MUCOCUTANEOUS LYMPH NODE SYNDROME; MUCOPOLYSACCHARIDOSIS; MULTIPLE MYELOMA; MYXEDEMA; NEOPLASM; ORAL MANIFESTATION; PERNICIOUS ANEMIA; PYOSTOMATITIS VEGETANS; REVIEW; RHEUMATOID ARTHRITIS; SARCOIDOSIS; SCLERODERMA; SJOEGREN SYNDROME; SYSTEMIC DISEASE; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC SCLEROSIS; THYROTOXICOSIS; WEGENER GRANULOMATOSIS;

AUTOIMMUNE DISEASES; ENDOCRINE SYSTEM DISEASES; GASTROINTESTINAL DISEASES; HEMATOLOGIC DISEASES; HUMANS; LUNG DISEASES; METABOLIC DISEASES; MOUTH DISEASES; NEOPLASMS;

EID: 78549236117     PISSN: 00306665     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.otc.2010.09.006     Document Type: Review

References (76)

1. McFarlane D.B., Pinderton P.H., Dagg J.H., et al. Incidence of iron deficiency, with and without anaemia, in women in general practice. Br J Haematol 1967, 13:790-796.
2. Zegarelli D.J. Fungal infections of the oral cavity. Otolaryngol Clin North Am 1993, 26:1069-1089.
3. Neville D., Allen B. Oral and maxillofacial pathology 2009, Saunders. 3rd edition.
4. Zimmer V., Buecker A., Lammert F. Sideropenic dysphagia. Gastroenterology 2009, 137:e1-e2.
5. Toh B.H., Alderuccio F. Pernicious anaemia. Autoimmunity 2004, 37:357-361.
6. Lynch M.A., Ship Initial oral manifestations of leukaemia. J Am Dent Assoc 1967, 75:932-940.
7. Subramaniam P., Babu K.L., Nagarathna J. Oral manifestations in acute lymphoblastic leukemic children under chemotherapy. J Clin Pediatr Dent 2008, 32:319-324.
8. Hiraki A., Nakamure S., Abe K., et al. Numb chin syndrome as an initial symptom of acute Lymphocytic leukemia: report of three cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997, 83:555-561.
9. Jones A.C., Bentsen T.Y., Freedman P.D. Mucormycosis of the oral cavity. Oral Surg Oral Med Oral Pathol 1993, 75:455-460.
10. Da Silva-Santos P.S., Silva B.S., Coracin L., et al. Granulocytic sarcoma of the oral cavity in a chronic myeloid leukemia patient: an unusual presentation. Med Oral Patol Oral Cir Bucal 2010, 15:e350-e352.
11. Madrigal-Martínez-Pereda C., Guerrero-Rodríguez V., Guisado-Moya B., et al. Langerhans cell histiocytosis: literature review and descriptive analysis of oral manifestations. Med Oral Patol Oral Cir Bucal 2009, 1(14):E222-E228.
12. Moraes Pde C., Bönecker M., Furuse C., et al. Langerhans cell histiocytosis in a child: a 10-year follow-up. Int J Paediatr Dent 2007, 17:211-216.
13. Mortellaro C., Pucci A., Palmeri A., et al. Oral manifestations of Langerhans cell histiocytosis in a pediatric population: a clinical and histological study of 8 patients. J Craniofac Surg 2006, 17:552-556.
14. Mozaffari E., Mupparapu M., Otis L. Undiagnosed multiple myeloma causing extensive dental bleeding: report of a case and review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002, 94:448-453.
15. Lee S.H., Huang J.J., Pan W.L., et al. Gingival mass as the primary manifestation of multiple myeloma: report of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996, 82:75-79.
16. Pinto L.S., Campagnoli E.B., Leon J.E., et al. Maxillary lesion presenting as a first sign of multiple myeloma: case report. Med Oral Patol Oral Cir Bucal 2007, 1(12):344-347.
17. Smith D.B. Multiple myeloma involving the jaws. Oral Surg Oral Med Oral Pathol 1957, 10:910-919.
18. Witt C., Borges A.C., Klein K., et al. Radiographic manifestations of multiple myeloma in the mandible: a retrospective study of 77 patients. J Oral Maxillofac Surg 1997, 55:450-453.
19. Reinish E.I., Raviv M., Srolovitz H., et al. Tongue, primary amyloidosis, and multiple myeloma. Oral Surg Oral Med Oral Pathol 1994, 77:121-125. 17.
20. Epstein I.B., Voss N.J.S., Stevenson-Moore P. Maxillofacial manifestations of multiple myeloma. Oral Surg Oral Med Oral Pathol 1984, 51:267-271.
21. Hernández-Molina G., Avila-Casado C., Cárdenas-Velázquez F., et al. Similarities and differences between primary and secondary Sjögren's syndrome. J Rheumatol 2010, 37:800-808.
22. Minozzi F., Galli M., Gallottini L., et al. Stomatological approach to Sjögren's syndrome: diagnosis, management and therapeutical timing. Eur Rev Med Pharmacol Sci 2009, 13:201-216.
23. Newbrun E. Current treatment modalities of oral problems of patients with Sjögren's syndrome: caries prevention. Adv Dent Res 1996, 10:29-34.
24. Atkinson J.C., Fox P.C. Sjögren's syndrome: oral and dental considerations. J Am Dent Assoc 1993, 124:74-86.
25. Biasi D., Caramaschi P., Ambrosetti A., et al. Mucosa-associated lymphoid tissue lymphoma of the salivary glands occurring in patients affected by Sjögren's syndrome: report of 6 cases. Acta Haematol 2001, 105:83-88.
26. Rowley A.H., Shulman S.T. Pathogenesis and management of Kawasaki disease. Expert Rev Anti Infect Ther 2010, 8:197-203.
27. Chung L., Lin J., Furst D.E., et al. Systemic and localized scleroderma. Clin Dermatol 2006, 24(5):374-392.
28. Rose L.F., Kaye D. Internal medicine for dentistry 1990, Mosby Yearbook, St. Louis (MO), p. 878-9, 93-94. 3rd edition.
29. Nagy G., Kovacs J., Zeger M., et al. Analysis of the oral manifestations for systemic sclerosis. Oral Surg Oral Med Oral Pathol 1994, 77:141-146.
30. Rout P.G., Hamburger J., Potts A.J. Orofacial radiological manifestations of systemic sclerosis. Dentomaxillofac Radiol 1996, 25:193-196.
31. Brennan M.T., Valerin M.A., Napeñas J.J., et al. Oral manifestations of patients with lupus erythematosus. Dent Clin North Am 2005, 49:127-141.
32. Nico M.M., Vilela M.A., Rivitti E.A., et al. Oral lesions in lupus erythematosus: correlation with cutaneous lesions. Eur J Dermatol 2008, 18:376-381.
33. Grennan D.M., Ferguson M., Williamson J., et al. Sjögren's syndrome in SLE. N Z Med J 1977, 86:374-379.
34. Voog U., Alstergren P., Eliasson S., et al. Progression of radiographic changes in the temporomandibular joints of patients with rheumatoid arthritis in relation to inflammatory markers and mediators in the blood. Acta Odontol Scand 2004, 62:7-13.
35. Theander E., Jacobsson L.T. Relationship of Sjögren's syndrome to other connective tissue and autoimmune disorders. Rheum Dis Clin North Am 2008, 34:935-947.
36. Serdar A., Basak D., Sercan G., et al. Solitary amyloid tumor of the tongue base. Int J Otolaryngol 2009, 2009:515068.
37. Elad S., Czerninski R., Fischman S., et al. Exceptional oral manifestations of amyloid light chain protein (AL) systemic amyloidosis. Amyloid 2010, 17:27-31.
38. Sadek I., Mauermann M.L., Hayman S.R., et al. Primary systemic amyloidosis presenting with asymmetric multiple mononeuropathies. J Clin Oncol 2010, 28(25):e429-e432.
39. Do Amaral B., Coelho T., Sousa A., et al. Usefulness of labial salivary gland biopsy in familial amyloid polyneuropathy Portuguese type. Amyloid 2009, 16:232-238.
40. Marzano A.V., Fanoni D., Berti E. Oral and cutaneous findings are valuable diagnostic aids in Wegener's granulomatosis. Eur J Intern Med 2010, 21:49.
41. Reboll R., Zapater E., Calabuig C., et al. Wegener's granulomatosis: description of a case with oral manifestation. Med Oral Patol Oral Cir Bucal 2010, 15(4):e601-e604.
42. Ruokonen H., Helve T., Arola J., et al. Strawberry like" gingivitis being the first sign of Wegener's granulomatosis. Eur J Intern Med 2009, 20:651-653.
43. Stewart C., Cohen D., Bhattacharyya I., et al. Oral manifestations of Wegener's granulomatosis: a report of three cases and a literature review. J Am Dent Assoc 2007, 138:338-348.
44. Marcoval J., Mañá J. Specific (granulomatous) oral lesions of sarcoidosis: report of two cases. Med Oral Patol Oral Cir Bucal 2010, 15:e456-e458.
45. Shenoy R., Al Burwani B. Necrotizing retinopathy simulating acute retinal necrosis causing rhegmatogenous retinal detachment in sarcoidosis: a case report. Eur J Ophthalmol 2010, 20:218-220.
46. Poate T.W., Sharma R., Moutasim K.A., et al. Orofacial presentations of sarcoidosis-a case series and review of the literature. Braz Dent J 2008, 25(205):437-442.
47. Miley D.D., Terezhalmy G.T. The patient with diabetes mellitus: etiology, epidemiology, principles of medical management, oral disease burden, and principles of dental management. Quintessence Int 2005, 36:779-795.
48. Mealey B.L., Oates T.W. Diabetes mellitus and periodontal diseases; American Academy of Periodontology. J Periodontol 2006, 77:1289-1303.
49. Mandel L., Patel S. Sialadenosis associated with diabetes mellitus: a case report. J Oral Maxillofac Surg 2002, 60:696-698.
50. Belazi M., Velegraki A., Fleva A., et al. Candidal overgrowth in diabetic patients: potential predisposing factors. Mycoses 2005, 48:192-196.
51. Zachariasen R.D. Xerostomia and the diabetic patient. J Gt Houst Dent Soc 1996, 67:10-13.
52. Falk H., Hugoson A., Thorstensson H. Number of teeth, prevalence of caries and periapical lesions in insulin-dependent diabetics. Scand J Dent Res 1989, 97:198-206.
53. Wysocki G.P., Daley T.D. Benign migratory glossitis in patients with juvenile diabetes. Oral Surg Oral Med Oral Pathol 1987, 63:68-70.
54. Roberts C.G., Ladenson P.W. Hypothyroidism. Lancet 2004, 363:793-803.
55. Topliss D.J., Eastman C.J. Diagnosis and management of hyperthyroidism and hypothyroidism. Med J Aust 2004, 180:186-193.
56. Pearce E.N. Diagnosis and management of thyrotoxicosis. BMJ 2006, 332:1369-1373.
57. Spiegel A.M. Hypoparathyroidism. Cecil's textbook of medicine 1992, 1419-1420. W.B. Saunders, Philadelphia. J.B. Wyngaarden, L.H. Smith, J.C. Bennett (Eds.).
58. Walls A.W.G., Soames J.V. Dental manifestations of autoimmune hypoparathyroidism. Oral Surg Oral Med Oral Pathol 1993, 75:452-454.
59. Aggunlu L., Akpek S., Coskun B. Leontiasis ossea in a patient with hyperparathyroidism secondary to chronic renal failure. Pediatr Radiol 2004, 34:630-632.
60. Solt D.B. The pathogenesis, oral manifestations, and implications for dentistry of metabolic bone disease. Curr Opin Dent 1991, 1(6):783-791.
61. Triantafillidou K., Zouloumis L., Karakinaris G., et al. Brown tumors of the jaws associated with primary or secondary hyperparathyroidism. A clinical study and review of the literature. Am J Otol 2006, 27:281-286.
62. Hayes C.W., Conway W.F. Hyperparathyroidism. Radiol Clin North Am 1991, 29:85-96.
63. Newell-Price J., Bertagna X., Grossman A.B., et al. Cushing's syndrome. Lancet 2006, 367:1605-1617.
64. Findling J.W., Raff H. Cushing's syndrome: important issues in diagnosis and management. J Clin Endocrinol Metab 2006, 91:3746-3753.
65. Chakera A.J., Vaidya B. Addison disease in adults: diagnosis and management. Am J Med 2010, 123:409-413.
66. Shah S.S., Oh C.H., Coffin S.E., et al. Addisonian pigmentation of the oral mucosa. Cutis 2005, 76:97-99.
67. Alpöz A.R., Coker M., Celen E., et al. The oral manifestations of Maroteaux-Lamy syndrome (mucopolysaccharidosis VI): a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006, 101:632-637.
68. Van den Bos T., Handoko G., Niehof A., et al. Cementum and dentin in hypophosphatasia. J Dent Res 2005, 84:1021-1025.
69. Batra P., Tejani Z., Mars M. X-linked hypophosphatemia: dental and histologic findings. J Can Dent Assoc 2006, 72:69-72.
70. Fatahzadeh M., Schwartz R.A., Kapila R., et al. Orofacial Crohn's disease: an oral enigma. Acta Dermatovenerol Croat 2009, 17:289-300.
71. Ojha J., Cohen D.M., Islam M.N., et al. Gingival involvement in Crohn disease. J Am Dent Assoc 2007, 138:1574-1581.
72. Pazheri F., Alkhouri N., Radhakrishnan K. Pyostomatitis vegetans as an oral manifestation of Crohn's disease in a pediatric patient. Inflamm Bowel Dis 2010, [Epub ahead of print]. DOI: 10.1002/ibd.21245.
73. Femiano F., Lanza A., Buonaiuto C., et al. Pyostomatitis vegetans: a review of the literature. Med Oral Patol Oral Cir Bucal 2009, 14:E114-E117.
74. Lim S.Y., Kim S.A., Ahn S.G., et al. Metastatic tumours to the jaws and oral soft tissues: a retrospective analysis of 41 Korean patients. Int J Oral Maxillofac Surg 2006, 35:412-415.
75. Van der Waal R.I., Buter J., van der Waal I. Oral metastases: report of 24 cases. Br J Oral Maxillofac Surg 2003, 41:3-6.
76. Yoshioka I., Shiiba S., Tanaka T., et al. The importance of clinical features and computed tomographic findings in numb chin syndrome: a report of two cases. J Am Dent Assoc 2009, 140:550-554.