Melanin-covered nanoparticles for protection of bone marrow during radiation therapy of cancer

International Journal of Radiation Oncology Biology Physics

Volumn 78, Issue 5, 2010, Pages 1494-1502

  Schweitzer, Andrew D ^a,b,c   Revskaya, Ekaterina ^a   Chu, Peter ^a   Pazo, Valeria ^d   Friedman, Matthew ^a   Nosanchuk, Joshua D ^a   Cahill, Sean ^a   Frases, Susana ^a   Casadevall, Arturo ^a   Dadachova, Ekaterina ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d JACOBI MEDICAL CENTER   (United States)

Author keywords

Bone marrow; Melanin; Nanoparticles; Radiation protection; Radioimmunotherapy

Indexed keywords

BIODISTRIBUTIONS; BODY WEIGHT; BONE MARROW; DIHYDROXYPHENYLALANINE; ENZYMATIC POLYMERIZATION; EXTERNAL BEAM RADIATION THERAPY; EXTERNAL RADIATION; HEMATOLOGIC TOXICITY; HUMAN BODIES; INTRAVENOUS ADMINISTRATION; MELANIN; MELANIN LAYERS; MELANOMA TUMORS; NATURALLY OCCURRING; NUDE MICE; PLURONICS; RADIATION THERAPY; RADICAL FORMATION; RADIOIMMUNOTHERAPY; RADIOTOXICITY; RIVER LABORATORIES; SILICA NANOPARTICLES; TUMOR PROTECTION; WHOLE-BODY;

ACIDS; BONE; FREE RADICALS; IONIZING RADIATION; LIGHT TRANSMISSION; NANOPARTICLES; POLYMERIZATION; RADIATION SHIELDING; RADIOACTIVITY; SILICA; TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

RADIOTHERAPY;

DOPA; EUMELANIN; MELANIN; PHENYLALANINE DERIVATIVE; PHEOMELANIN; RHENIUM 188; SILICON DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; BONE MARROW TOXICITY; CANCER RADIOTHERAPY; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DRUG STRUCTURE; EXTERNAL BEAM RADIOTHERAPY; IMMUNOFLUORESCENCE; ISOTOPE LABELING; LIGHT SCATTERING; MOUSE; NONHUMAN; NUDE MOUSE; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; RADIOIMMUNOTHERAPY; RISK ASSESSMENT; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; BONE MARROW; DRUG CARRIERS; MAGNETIC RESONANCE SPECTROSCOPY; MELANINS; MELANOMA; MICE; MICE, NUDE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; RADIOIMMUNOTHERAPY;

EID: 78549234658     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.02.020     Document Type: Article

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