The complexity of high-density lipoproteins

Circulation

Volumn 122, Issue 19, 2010, Pages 1900-1901

  Fogelman, Alan M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

apolipoproteins; atherosclerosis; Editorials; HDL cholesterol; infection; inflammation

Indexed keywords

APOLIPOPROTEIN A1; BETA INTERFERON; HIGH DENSITY LIPOPROTEIN; INTERFERON; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 2;

EDITORIAL; HUMAN; IMMUNE RESPONSE; LIPID TRANSPORT; MACROPHAGE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; VIRUS INFECTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOLIPOPROTEINS; ATHEROSCLEROSIS; CHOLESTEROL, HDL; HUMANS; LIPOPOLYSACCHARIDES; LIPOPROTEINS, HDL; MACROPHAGES; MEMBRANE LIPIDS;

EID: 78549232225     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.110.984120     Document Type: Editorial

References (20)

1. Eisenberg S. High density lipoprotein metabolism. J Lipid Res. 1984;25: 1017-1058.
2. Suzuki M, Pritchard DK, Becker L, Hoofnagle AN, Tanimura N, Bammler TK, Beyer RP, Bumgarner R, Vaisar T, de Beer MC, de Beer FC, Miyake K, Oram JF, Heinecke JW. High-density lipoprotein suppresses the type I interferon response, a family of potent antiviral immu-noregulators, in macrophages challenged with lipopolysaccharide. Circulation. 2010;122:1919-1927.
3. Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R. TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-b. Nat Immunol. 2008;9:361-368.
4. Luke AJ, Bowie AG. Sensing and signaling in antiviral innate immunity. Curr Biol. 2010;20:R328-R333.
5. Hall JC, Rosen A. Type I interferons: crucial participants in disease amplification in autoimmunity. Nat Rev Rheumatol. 2010;6:40-49.
6. Van Lenten BJ, Wagner AC, Navab M, Anantharamaiah GM, Hui EK-W, Nayak DP, Fogelman AM. D-4F, an apolipoprotein A-I mimetic peptide, inhibits the inflammatory response induced by influenza A infection of human type II pneumocytes. Circulation. 2004;110:3252-3258.
7. Van Lenten BJ, Wagner AC, Anantharamaiah GM, Garber DW, Fishbein MC, Adhikary L, Nayak DP, Hama S, Navab M, Fogelman AM. Influenza infection promotes macrophage traffic into arteries of mice that is prevented by D-4F, an apolipoprotein A-I mimetic peptide. Circulation. 2002;106:1127-1132.
8. Van Lenten BJ, Wagner AC, Jung C-L, Ruchala P, Waring AJ, Lehrer RI, Watson AD, Hama S, Navab M, Anantharamaiah GM, Fogelman AM. Anti-inflammatory apoA-I mimetic peptides bind oxidized lipids with much higher affinity than human apoA-I. J Lipid Res. 2008;49: 2302-2311.
9. Walton KA, Cole AL, Yeh M, Subbanagounder G, Krutzik SR, Modlin RL, Lucas RM, Nakai J, Smart EJ, Vora DK, Berliner JA. Specific phospholipid oxidation products inhibit ligand activation of Toll-like receptors 4 and 2. Arterioscler Thromb Vasc Biol. 2003;23:1197-1203.
10. Walton KA, Gugiu BG, Thomas M, Basseri RJ, Eliav DR, Salomon RG, Berliner JA. A role for neutral sphingomyelinase activation in the inhibition of LPS by phospholipid oxidation products. J Lipid Res. 2006;47: 1967-1974.
11. Smythies LE, White CR, Maheshwari A, Palgunachari MN, Anantharamaiah GM, Chaddha M, Kurundkar AR, Datta G. Apolipoprotein A-I mimetic 4F alters the function of human monocyte-derived macrophages. Am J Physiol. 2010;298:C1538-C1548.
12. Gharavi NM, Gargalovic PS, Chang I, Araujo JA, Clark MJ, Szeto WL, Watson AD, Lusis AJ, Berliner JA. High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory. Arterioscler Thromb Vasc Biol. 2007; 27:1346-1353.
13. Subbanagounder G, Wong JW, Lee H, Faull KF, Miller E, Witztum JL, Berliner JA. Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-I synthesis: formation of these oxidized phospholipids in response to interleukin-1/3. J Biol Chem. 2002;277:7271-7281.
14. Chang M-K, Binder CJ, Miller YI, Subbangounder G, Silverman GJ, Berliner JA, Witztum JL. Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory. J Exp Med. 2004;200: 1359-1370.
15. Cruz D, Watson AD, Miller CS, Montoya D, Ochoa M-T, Sieling PA, Gutierrez MA, Navab M, Reddy ST, Witztum JL, Fogelman AM, Rea TH, Eisenberg D, Berliner JA, Modlin RL. Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy. J Clin Invest. 2008;118:2917-2928.
16. Berliner JA, Watson AD. A role for oxidized phospholipids in atherosclerosis. N Engl J Med. 2005;353:9-11.
17. Knapp S, Matt U, Leitinger N, van der Poll T. Oxidized phospholipids inhibit phagocytosis and impair outcome in gram-negative sepsis in vivo. The J Immunol. 2007;178:993-1001.
18. Dai L, Datta G, Zhang Z, Gupta H, Patel R, Honavar J, Modi S, Wyss JM, Palgunachari M, Anantharamaiah GM, White CR. The apolipoprotein A-I mimetic peptide 4F prevents defects in vascular function in endotoxemic rats. J Lipid Res. 2010;51:2695-2705.
19. Vaisar T, Pennathur S, Green PS, Gharib SA, Hoofnagle AN, Cheung MC, Byun J, Vuletic S, Kassim S, Singh P, Chea H, Knopp RH, Brunzell J, Geary R, Chait A, Zhao X-Q, Elkon K, Marcovina S, Ridker P, Oram JF, Heinecke JW. Shotgun proteomics implicates protease inhibition and complement activation in the anti-inflammatory properties of HDL. J Clin Invest. 2007;117:746-756.
20. Hoofnagle AN, Heinecke JW. Lipoproteomics: using mass spectrometry-based proteomics to explore the assembly, structure and function of lipoproteins. J Lipid Res. 2009;50:1967-1975.